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  • 1
    ISSN: 0248-4900
    Keywords: Paramecium ; anti-tubulin antibodies ; axoneme ; cilia ; isotype ; microtubules ; post-translational modification ; quall ; tubulin
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-601X
    Keywords: 21.10.−k ; 27.20.+n ; 25.70.Np ; 21.10.Re
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Total interaction cross sections have been measured for8Li on C and Pb targets, for9Li on C, Al, Cu, Sn and Pb targets as well as for11Li on C, Sn and Pb targets. For each beam, we also used a plastic scintillator as target. The measurements with the scintillator targets are used to extract reduced nuclear radii of the lithium isotopes. These radii are then used for the calculation of the nuclear part of the total cross section for the other targets. The total electromagnetic-dissociation (EMD) cross sections have been deduced and are compared to different models. A strong target-charge-dependent EMD cross section is measured for11Li reaching 2.96 −0.82 +0.84 b for the Pb target. In the9Li case, a large EMD cross section for high-Z targets has been observed which amounts to 0.75 ± 0.45 b for the Pb target. The EMD cross sections of both,9Li and11Li, may be understood by the giantdipole-resonance model.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1615-6102
    Keywords: Paramecium ; Microtubule diversity ; Cellular morphogenesis ; Immunofluorescence ; Tubulin post-translational modification
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Ciliates are highly differentiated cells which display extensive deployment of microtubular systems. Because genetic diversity of tubulin is extremely reduced in these cells, microtubule diversity is mostly generated at the post-translational level either through direct modification of tubulin or through the binding of associated proteins to microtubules. We have undertaken a systematic exploration of microtubule diversity in ciliates by way of production of monoclonal antibodies. Previously we reported the biochemical characterization of these antibodies. In addition to antibodies directed against primary sequences, we obtained antibodies directed against post-translational modifications. In this paper, we report a detailed analysis of the distribution of the various epitopes on the microtubular networks ofParamecium, both in interphase cells and during division morphogenesis. Each of these antibodies decorates a subset of microtubules. Acetylation, recognized by antibodies TEU 318 and TEU 348, is detected on stable microtubules early after microtubule assembly. Epitopes recognized by two other antibodies (TAP 952 and AXO 58) are found on a subset of stable microtubules; in addition, the TAP 952 antibody is also found on labile microtubules; both epitopes are detected as soon as microtubule assembly occurs. In contrast, the epitope of the antibody, AXO 49, is associated with only a restricted subset of stable microtubules in the interphase cell, and is detected a lag-time after microtubule assembly during division morphogenesis. These data show that microtubule diversity is generated through a time-dependent sequence and according to a definite spatial pattern.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1434-601X
    Keywords: 21.10.−k ; 27.20.+n ; 25.70.Np ; 21.10.Re
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Total charge-changing cross sections have been measured for8Li on C and Pb targets, for9Li on C, Al, Cu, Sn and Pb targets, as well as for11Li on C, Sn and Pb targets at about 80 MeV/nucleon. These data are compared to measured total reaction cross sections and Glauber-type calculations using Hartree-Fock density distributions. These comparisons allow to draw conclusions on the proton density distribution of the neutronrich lithium isotopes. The results show that even for the most exotic nucleus11Li the proton distribution is only very weakly influenced by the long tail in the neutron density distribution already established in several experiments.
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 27 (1994), S. 337-349 
    ISSN: 0886-1544
    Keywords: microtubules ; glutamylation ; Paramecium ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Microtubular networks are extensively developped in many ciliate species. In several of them, we investigate the occurrence of the post-translational glutamylation of tubulin [Eddé et al., 1990: Science 247:82-85; Eddé et al., 1991: J. Cell. Biochem. 46:134-142] using as a probe for such modified tubulin, the monoclonal antibody GT335 [Wolff et al., 1992: Eur. J. Cell Biol. 59:425-432]. Results obtained in Paramecium strongly suggest that both axonemal and cytoplasmic tubulin are glutamylated. As in the vertebrate brain tubulin so far tested, the GT335 epitope is located at the carboxy-terminal fragment of cytoplasmic tubulin removed by subtilisin treatment. Immunoblotting and immunofluorescence experiments reveal that, unlike tubulin acetylation, glutamylation is not restricted to cold-resistant microtubules. In addition, immunofluorescence studies performed on dividing cells show that glutamylation takes place soon after the polymerization of microtubules.Finally, glutamylated tubulin is also detected in the ciliate species Euplotes, Tetrahymena, and Paraurostyla. Together with results obtained on flagellate species, this suggests that tubulin glutamylation came out early in the course of eukaryotic evolution and has been widely exploited in various cellular strategies. © 1994 Wiley-Liss, Inc.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 6
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    SciELO Books - Editora FIOCRUZ
    Publication Date: 2023-12-20
    Description: Trata do sistema de instituições jurídicas e políticas de proteção social, com o objetivo central de apresentar ao leitor o padrão latino-americano de Seguridade Social, analisando suas origens, forma e tendências de desenvolvimento. A autora não se furta à polêmica: aceita o desafio acadêmico de construir um ponto de vista teórico com força suficiente para enfrentar os inevitáveis - e, para o debate, instigantes - questionamentos. Enfim: leitura obrigatória para os que querem entender e interferir nos rumos da Seguridade da América Latina, quaisquer sejam suas formações profissionais e convicções políticas.
    Keywords: H1-99 ; Política social - América Latina ; Previdência social - América Latina ; Assistência Pública - América Latina ; bic Book Industry Communication::H Humanities
    Language: Portuguese
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  • 7
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    Presses universitaires de Rennes
    Publication Date: 2023-12-20
    Description: Dégagé de la plupart de ses contrepouvoirs depuis la fin des années 1980, le projet politique néolibéral et les inégalités qu’il renforce paraissent aujourd’hui sans remède. Est-il si difficile de ne pas céder à la résignation ou, pire, à l’indifférence ? Les outils pour identifier ces inégalités, les expliquer et les dénoncer ne manquent pas. La pensée critique connaît, en France comme ailleurs, un formidable renouveau. Dans toutes les disciplines des sciences sociales, l’apport de nos aînés est revisité et enrichi de nouvelles propositions pour se confronter aux injustices contemporaines, qui semblent rendues acceptables par des manipulations intellectuelles et des ficelles de plus en plus grossières. L’espace est, comme le temps et l’argent, un redoutable allié des dominants. Accaparé, exproprié, spolié, marchandisé, financiarisé, surveillé, refusé, l’espace se révèle être, à toutes les échelles et dans toutes ses configurations, une excellente clef de lecture de la situation des dominés. Confinement, relégation, enfermement en sont les modalités extrêmes, mais bien d’autres, plus subtiles et moins visibles, contribuent à pérenniser des rapports de force à ce point asymétriques qu’il n’est de meilleur terme pour les qualifier que celui de domination. Mais l’espace est aussi l’allié des dominés engagés dans des processus de résistance, de contestation ou de lutte contre l’ordre du capitalisme néolibéral. Dotés de ressources propres, les dominés construisent aussi des stratégies, individuelles ou collectives, qui prennent appui dans l’espace et peuvent faire de ce dernier une ressource pour se faire entendre ou se rendre visible. Dans un contexte académique mondial dominé par les travaux anglophones, en particulier ceux de la géographie radicale, cet ouvrage entend présenter la manière dont les chercheurs et chercheuses francophones travaillant sur les questions spatiales analysent les rapports sociaux de domination, qu’ils soient de classe, de race, de sexe, autant de rapports sociaux qui ont un fondement matériel. Plusieurs entrées thématiques sont explorées, qui renvoient à des champs de recherche bien identifiés : la question urbaine, les études sur le genre, le sexe, la sexualité et l’intersectionnalité, la question des migrations et celle des populations marginalisées et, enfin, l’environnement. Cet ouvrage témoigne donc de la grande vivacité des travaux francophones, tout en réaffirmant l’utilité de penser l’espace dans la critique sociale.
    Keywords: H1-99 ; espace ; inégalité sociale ; géographie sociale ; domination sociale ; bic Book Industry Communication::H Humanities
    Language: French
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  • 8
    Publication Date: 2023-12-20
    Keywords: H1-99 ; ville ; intégration sociale ; espace ; vie urbaine ; culture ; ségrégation ; France ; sociologie ; bic Book Industry Communication::H Humanities
    Language: French
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