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  • Animals  (7)
  • American Association for the Advancement of Science (AAAS)  (7)
  • 1980-1984  (7)
  • 1
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    Eye dominance columns from an isogenic double-nasal frog eye (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-07-15
    Description: Removing the posterior (temporal) two-thirds of the Xenopus eye bud produces a remaining fragment, which becomes round and grows to a normal adult size eye. Electrophysiological and anatomical analyses showed that each of the two halves of this eye projected across the entire optic tectum in mirror image (double-nasal) fashion, and that fibers from each half-eye sorted out to form eye dominance stripes on the tectum. That both halves of the mirror-symmetric map were derived from only one animal, and from only one side of the head, rules out global markers such as right versus left and histocompatibility differences as causing the formation of these stripes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ide, C F -- Fraser, S E -- Meyer, R L -- NS16319/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1983 Jul 15;221(4607):293-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6857287" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Electrophysiology ; Eye/*innervation ; Optic Nerve/physiology ; Retina/physiology ; Superior Colliculi/physiology ; Vision, Ocular/*physiology ; Xenopus
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Origin of the cholecystokinin-containing fibers in the rat caudatoputamen (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-01-08
    Description: Large Amounts of cholecystokinin-octapeptide (CCK) are present in the rat caudatoputamen. The peptide occurs in axons and nerve endings but not in perikarya. The origin of CCK in the caudatoputamen was investigated with the use of immunocytochemistry and a radioimmunoassay specific for CCK. Although a small amount of CCK (approximately 30 percent) originates in the amygdaloid complex, the bulk of the peptide (approximately 70 percent) occurs in processes of neurons located ventral to the caudatoputamen, that is, the claustrum or the piriform cortex. The claustrum and piriform cortex receive inputs from various cortical areas and the olfactory system, respectively, and may process information and relay it to the caudatoputamen. Thus CCK may by the transmitter in the final common pathway linking various cortical areas and the olfactory system to the caudatoputamen.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meyer, D K -- Beinfeld, M C -- Oertel, W H -- Brownstein, M J -- New York, N.Y. -- Science. 1982 Jan 8;215(4529):187-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7053570" target="_blank"〉PubMed〈/a〉
    Keywords: Amygdala/cytology ; Animals ; Caudate Nucleus/cytology/*metabolism ; Cerebral Cortex/cytology ; Cholecystokinin/*metabolism ; Female ; Neural Pathways/cytology ; Putamen/cytology/*metabolism ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    High-affinity choline transport in proteoliposomes derived from rat cortical synaptosomes (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-08-27
    Description: Functional high- and low-affinity choline transport processes from rat cortical plasma membranes were reconstituted in phosphatidylcholine bilayer liposomes. The high-affinity choline transporter demonstrated a pharmacological profile and ion dependency that were identical to those of intact synaptosomes. This preparation may be used to further characterize choline transport and, with appropriate supplementation, to investigate the release of acetylcholine in the absence of synaptic vesicles.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meyer, E M -- Cooper, J R -- NS 09836/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1982 Aug 27;217(4562):843-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7100928" target="_blank"〉PubMed〈/a〉
    Keywords: Acetylcholine/metabolism ; Animals ; Biological Transport ; Cell Membrane/metabolism ; Chlorides/metabolism ; Choline/*metabolism ; Kinetics ; Lipid Bilayers/metabolism ; Liposomes/*metabolism ; Phosphatidylcholines/metabolism ; Rats ; Sodium/metabolism ; Synaptosomes/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Tetrodotoxin blocks the formation of ocular dominance columns in goldfish (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-11-05
    Description: Optic fibers from both eyes were made to regenerate simultaneously into one tectum in goldfish. Autoradiography at various times later revealed that regenerating left and right fibers overlapped extensively for up to 4 weeks and subsequently segregated into eye dominance columns by 8 weeks. Continuous tetrodotoxin treatment of both eyes prevented the formation of columns for up to 13 weeks and was equally effective if begun at 6 weeks. When tetrodotoxin treatment was stopped after 11 weeks, columns subsequently formed in the next 3 weeks. Blockade of only one eye did prevent column formation at 8 weeks.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meyer, R L -- NS15381/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1982 Nov 5;218(4572):589-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7123262" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Functional Laterality ; Goldfish ; Nerve Regeneration/drug effects ; Neuronal Plasticity/*drug effects ; Tetrodotoxin/*pharmacology ; Visual Pathways/drug effects/*growth & development
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Myelinated nociceptive afferents account for the hyperalgesia that follows a burn to the hand (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-09-25
    Description: Monkeys and human subjects were exposed to a series of thermal stimuli before and after a 53 degrees C, 30-second burn to the glabrous skin of the hand. The responses of C- and A-fiber nociceptive afferents in the monkeys and subjective responses by the humans were compared. The burn resulted in increased sensitivity of the A fibers, decreased sensitivity of the C fibers, and increased pain sensibility (hyperalgesia) in the human subjects.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meyer, R A -- Campbell, J N -- NS-00519/NS/NINDS NIH HHS/ -- NS-14447/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 Sep 25;213(4515):1527-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7280675" target="_blank"〉PubMed〈/a〉
    Keywords: Afferent Pathways/physiology ; Animals ; Burns/*physiopathology ; Hand/innervation ; Humans ; Hyperalgesia/*physiopathology ; Hyperesthesia/*physiopathology ; Macaca ; Nerve Fibers/physiology ; Nerve Fibers, Myelinated/*physiology ; Nociceptors/*physiology ; Pain/*physiopathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Virus-induced corticosterone in hypophysectomized mice: a possible lymphoid adrenal axis (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-12-24
    Description: Infection of hypophysectomized mice with Newcastle disease virus caused a time-dependent increase in corticosterone and interferon production. Prior treatment with dexamethasone completely inhibited the virus-induced elevation in corticosterone concentration, but did not significantly alter the interferon response. Lymphocytes appear to be the most likely source of an adrenocorticotropin-like substance that is responsible for the increased corticosterone, since spleen cells from the virus-infected, but not from control or dexamethasone-treated, hypophysectomized mice showed positive immunofluorescence with antibody to adrenocorticotropin-(1-13 amide). Thus the adrenocorticotropin-like material and interferon appear to be coordinately induced the differentially controlled products of different genes. These findings strongly suggest the existence of a lymphoid-adrenal axis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, E M -- Meyer, W J -- Blalock, J E -- AM30046/AM/NIADDK NIH HHS/ -- HL20201/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1982 Dec 24;218(4579):1311-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6183748" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenal Glands/*physiology ; Animals ; Corticosterone/*biosynthesis ; Dexamethasone/pharmacology ; *Hypophysectomy ; Interferons/biosynthesis ; Kinetics ; Lymph Nodes/*physiology ; Mice ; Newcastle Disease/*metabolism ; Time Factors
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    Efferents to the retina have multiple sources in teleost fish (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-11-20
    Description: Multiple efferent systems project to the retina in three species of teleost fish investigated with the horseradish peroxidase technique. These animals are the first vertebrates shown to have more than one central nervous system structure projecting to the retina. The connections discovered may reflect a primitive organization of retina-brain interconnections.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ebbesson, S O -- Meyer, D L -- New York, N.Y. -- Science. 1981 Nov 20;214(4523):924-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6171033" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Axonal Transport ; Efferent Pathways/*physiology ; Fishes ; Horseradish Peroxidase ; Retina/*physiology ; Species Specificity
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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