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  • 1
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    Vectorcardiographic changes during extended space flight (M093): Observations at rest and during exercise (1977)
    In:  CASI
    Details
    Publication Date: 2006-01-16
    Description: The objectives of Skylab Experiment M093 were to measure electrocardiographic signals during space flight, to elucidate the electrophysiological basis for the changes observed, and to assess the effect of the change on the human cardiovascular system. Vectorcardiographic methods were used to quantitate changes, standardize data collection, and to facilitate reduction and statistical analysis of data. Since the Skylab missions provided a unique opportunity to study the effects of prolonged weightlessness on human subjects, an effort was made to construct a data base that contained measurements taken with precision and in adequate number to enable conclusions to be made with a high degree of confidence. Standardized exercise loads were incorporated into the experiment protocol to increase the sensitivity of the electrocardiogram for effects of deconditioning and to detect susceptability for arrhythmias.
    Keywords: AEROSPACE MEDICINE
    Type: NASA. JSC Biomed. Results from Skylab; p 339-350
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  • 2
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    Bone mineral measurement: Experiment M078 (1977)
    In:  CASI
    Details
    Publication Date: 2006-01-16
    Description: Gamma ray absorptiometric measurements on bone mineral content, in addition to calcium balance studies, were performed on male volunteers during bed rest periods of 24 to 36 weeks duration and compared to Skylab mission data. Results show that mineral losses occur from the bones of the lower extremities during missions of up to 84 days and that in general they follow the loss patterns of the bed rest situation. The level of loss observed in Spacelab crews are not of clinical concern.
    Keywords: AEROSPACE MEDICINE
    Type: Biomed. Results from Skylab; p 183-190
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  • 3
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    Mineral and nitrogen metabolic studies, experiment M071 (1977)
    In:  CASI
    Details
    Publication Date: 2006-01-16
    Description: The similarity between bed rest test and space flight effects on human mineral and nitrogen metabolisms indicates impairment of capable musculoskeletal functions. A pattern of urinary calcium increases and total calcium shifts suggests that calcium losses continue with time. Significant losses of nitrogen and phosphorus are associated with reduction in muscle tissue. It is concluded that capable musculoskeletal function is likely to be impaired during space flights of 1 1/2 to 3 years duration.
    Keywords: AEROSPACE MEDICINE
    Type: Biomed. Results from Skylab; p 164-174
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  • 4
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    Principles of gravitational biology (1975)
    In:  CASI
    Details
    Publication Date: 2006-01-12
    Description: Physical principles of gravitation are enumerated, including gravitational and inertial forces, weight and mass, weightlessness, size and scale effects, scale limits of gravitational effects, and gravity as biogenic factor. Statocysts, otolithic organs of vertebrates, gravity reception in plants, and clinostat studies for gravitation orientation are reviewed. Chronic acceleration is also studied, as well as physiology of hyper and hypodynamic fields. Responses of animals to a decreased acceleration field are examined, considering postural changes, work capacity, growth, and physiologic deadaptation.
    Keywords: AEROSPACE MEDICINE
    Type: NASA, Washington Found. of Space Biol. and Med., Vol. 2, Bk. 1; p 129-162
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  • 5
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    Nutritional studies (1975)
    In:  CASI
    Details
    Publication Date: 2006-01-12
    Description: Detailed metabolic studies were conducted of the Apollo 16 and Apollo 17 flight crews, and the results are presented in tabular form. Intake and absorption data are also included. Apollo nutrient intakes were found to be characteristically hypocaloric. Estimates of body composition changes from metabolic balance data, from preflight and postflight weights and volumes, and from total body water and potassium provide no evidence for diminished caloric requirements during a flight. As observed during the Gemini Program and during periods of bed rest, measurements of bone density and metabolic balance confirm a tendency toward loss of skeletal tissue in weightlessness. No evidence exists that any inflight metabolic anomaly, including hypokalemia, was induced by marginal or deficient nutrient intakes. In general, the Apollo crewmen were well nourished and exhibited normal gastroenterological functions, although appetite was somewhat diminished and the organoleptic response to food was somewhat modified during flight.
    Keywords: AEROSPACE MEDICINE
    Type: Biomedical Results of Apollo; p 277-302
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  • 6
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    Skeletal response (1975)
    In:  CASI
    Details
    Publication Date: 2006-01-12
    Description: The effect of weightlessness on bone mineral content during prolonged space flight was investigated. The mineral content changes which occurred during Apollo 14, 15, and 16 as measured by photon absorptiometry techniques are presented and compared. Bed rest served as an experimental model to assess the bone mineral changes, and to determine what remedial measures might be used to stem the tide of bone mineral loss. It is concluded that loss of mineral from bone due to the state of weightlessness is comparable to that observed in bed rest subjects.
    Keywords: AEROSPACE MEDICINE
    Type: Biomedical Results of Apollo; p 303-322
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  • 7
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    Apollo food technology (1975)
    In:  CASI
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    Publication Date: 2006-01-12
    Description: Large improvements and advances in space food systems achieved during the Apollo food program are discussed. Modifications of the Apollo food system were directed primarily toward improving delivery of adequate nutrition to the astronaut. Individual food items and flight menus were modified as nutritional countermeasures to the effects of weightlessness. Unique food items were developed, including some that provided nutritional completeness, high acceptability, and ready-to-eat, shelf-stable convenience. Specialized food packages were also developed. The Apollo program experience clearly showed that future space food systems will require well-directed efforts to achieve the optimum potential of food systems in support of the physiological and psychological well-being of astronauts and crews.
    Keywords: AEROSPACE MEDICINE
    Type: Biomedical Results of Apollo; p 437-468
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  • 8
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    Mineral and nitrogen balance study - Results of metabolic observations on Skylab II 28-day orbital mission (1975)
    In:  Other Sources
    Details
    Publication Date: 2011-08-16
    Description: The prediction that various stresses of flight, particularly weightlessness, would bring about significant derangements in the metabolism of the musculoskeletal system has been based on various balance-study observations of long-term immobilized or inactive bed rest. The three astronauts of Skylab II consumed a planned dietary intake of major metabolic elements in mixed foods and beverages and provided virtually complete collections of excreta for 31 days preflight, 28 days inflight, and 17 days postflight. Analyses showed that, in varying degree among the crewmen, urinary calcium increased gradually during flight in a pattern similar to that observed in bed-rest studies. Fecal calcium excretion did not change significantly, but calcium balance, owing to the urinary calcium rise, became either negative or less positive than in preflight measurement. Increased excretion and negative nitrogen and phosphorus balances inflight indicated appreciable loss of muscle tissue in all three crewmen. Significant losses also occurred inflight in potassium, sodium, and magnesium. Based on the similarity in pattern and degree between these observations of calcium, phosphorus, and nitrogen loss, musculoskeletal integrity would not be threatened in space flights of up to at least 3 months. However, if similar changes occur in the planed Skylab flights for considerably more than 28 days, concern for capable musculoskeletal function should be serious for flights of very many months' duration.
    Keywords: AEROSPACE MEDICINE
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  • 9
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    Mineral and nitrogen balance study observations - The second manned Skylab mission (1976)
    In:  Other Sources
    Details
    Publication Date: 2011-08-16
    Description: A metabolic study of important body elements, particularly those of the musculoskeletal system, was carried out on the astronauts of the Skylab 3 mission during the preflight, inflight, and postflight phases. An elevation in the level of urinary calcium similar to that observed in the 28-d Skylab flight continued throughout the flight. Significant nitrogen and phosphorus losses, apparently associated with muscle tissue loss, occurred in spite of inflight exercise programs. On the basis of these results it is predicted that capable musculoskeletal function is likely to occur in flights longer than about 9 months in duration.
    Keywords: AEROSPACE MEDICINE
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  • 10
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    Myocardial blood flow: Roentgen videodensitometry techniques (1975)
    In:  Other Sources
    Details
    Publication Date: 2019-01-25
    Description: The current status of roentgen videodensitometric techniques that provide an objective assessment of blood flow at selected sites within the coronary circulation were described. Roentgen videodensitometry employs conventional radiopaque indicators, radiological equipment and coronary angiographic techniques. Roentgen videodensitometry techniques developed in the laboratory during the past nine years, and for the past three years were applied to analysis of angiograms in the clinical cardiac catheterization laboratory.
    Keywords: AEROSPACE MEDICINE
    Type: Soc. of Photo-Opt. Instrumentation Engrs. Cardiovascular Imaging and Image Processing; p 225-232
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