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  • Articles  (99)
  • Springer  (99)
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  • Articles  (99)
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  • 1
    Electronic Resource
    Electronic Resource
    Induction of apoptosis in proliferating lymphocytes by tricyclic antidepressants (1998)
    Springer
    Apoptosis 3 (1998), S. 255-260 
    Details
    ISSN: 1573-675X
    Keywords: Antidepressants ; apoptosis ; induction ; lymphoblasts ; lymphocytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract We have previously found that tricyclic antidepressants (TCAs) induce apoptosis in quiescent human lymphocytes. The aim of the present study was to evaluate if TCAs induce apoptosis in proliferating human lymphocytes and in established blastoid lymphocytes also. The development of conA-induced lymphoblast populations was followed by measuring the CD25 membrane expression. Three TCA compounds were run with the following concentrations: imipramine (10, 20, 30, 40, 60μ M), clomipramine (1, 10, 20, 30, 40μ M) and citalopram (40, 60, 80, 100, 180μ M). They all induced a dose-dependent apoptosis both in continuously transformed, as well as in established lymphoblasts. Preincubation of the TCA up to 48 h did not significantly increase induction of apoptosis. The three drugs tested were found to be potent inducers of apoptosis in proliferating lymphocytes. Furthermore, we found that the apoptotic populations in proliferating and in established blastoid lymphocytes were of f airly the same magnitude than in the corresponding population in TCA-incubated resting lymphocytes. In conclusion, we demonstrate that TCAs induce apoptosis in proliferating lymphocytes, as they do in quiescent lymphocytes. Furthermore, the exent of apoptosis was even more pronounced in TCA-incubated lymphoblasts compared to TCA-treated resting lymphocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009609224936
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  • 2
    Electronic Resource
    Electronic Resource
    Cu-like Pd and Ag inner-shell photoionization phenomena (1996)
    Springer
    Applied physics 62 (1996), S. 619-622 
    Details
    ISSN: 1432-0649
    Keywords: 52.50.Jm ; 52.25.Nr
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We have obtained results for converting focused laser radiation to X-ray line emissions in laser-heated NaF and Cu plasmas. These plasmas were used as the pump source for studying the phenomena of inner-shell photoionization of Zn-like ionic states. Soft X-ray emissions from transitions of 3d 94s 2 → 3d 104p in Cu-like Pd and Ag ions were observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01081701
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  • 3
    Electronic Resource
    Electronic Resource
    Coupling of element free Galerkin and hybrid boundary element methods using modified variational formulation (2000)
    Springer
    Computational mechanics 26 (2000), S. 166-173 
    Details
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  A novel method is proposed by coupling the element free Galerkin (EFG) and the hybrid boundary element (HBE) methods to achieve solution efficiency and accuracy for stress analysis in solids. A modified variational formulation is derived for the present coupled EFG/HBE method so that the continuity and compatibility can be preserved on the interface between the domains of EFG and HBE. The coupled EFG/HBE method has been coded in FORTRAN. The validity and efficiency of the proposed method are demonstrated through a number of example problems. It is found that the present method can take advantages of both EFG and HBE methods. The present method is very easy to implement, and very flexible for obtaining displacements and stresses of desired accuracy in solids, as the efforts for meshing the problem domain have been significantly reduced due to the use of boundary element method (BEM).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004660000164
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  • 4
    Electronic Resource
    Electronic Resource
    Meshless local Petrov–Galerkin (MLPG) method in combination with finite element and boundary element approaches (2000)
    Springer
    Computational mechanics 26 (2000), S. 536-546 
    Details
    ISSN: 1432-0924
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The meshless local Petrov–Galerkin (MLPG) method is an effective truly meshless method for solving partial differential equations using moving least squares (MLS) interpolants. It is, however, computationally expensive for some problems. A coupled MLPG/finite element (FE) method and a coupled MLPG/boundary element (BE) method are proposed in this paper to improve the solution efficiency. A procedure is developed for the coupled MLPG/FE method and the coupled MLPG/BE method so that the continuity and compatibility are preserved on the interface of the two domains where the MLPG and FE or BE methods are applied. The validity and efficiency of the MLPG/FE and MLPG/BE methods are demonstrated through a number of examples.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004660000203
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  • 5
    Electronic Resource
    Electronic Resource
    Lily cofactor-independent phosphoglycerate mutase: purification, partial sequencing, and immunolocalization (1996)
    Springer
    Planta 200 (1996), S. 343-352 
    Details
    ISSN: 1432-2048
    Keywords: Antibody production ; Enzyme immunolocalization ; Lilium ; Phosphoglycerate mutase (cofactor independent) ; Vitronectin antibody
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A cofactor-independent phosphoglycerate mutase (PGAM-i) was isolated to homogeneity from monocotyledonous Lilium longiflorum Thunb. Two-dimensional (2D) polyacrylamide gel electrophoresis resolved three PGAM-i forms. This enzyme was originally identified by cross-reactivity to antibodies affinity-purified from 2D gels using human vitronectin (VN). Antibody produced against a denatured protein spot from a 2D gel did not recognize VN protein, but partial protein and DNA sequencing showed similarity of the former protein to maize PGAM-i. Immunoblots from roots, styles, leaves, and anthers showed the presence of PGAM-i in all tissues examined; it was isolated predominantly from the soluble cell fraction, with some present in the insoluble cell fraction. Immunoelectron microscopy demonstrated its localization in the cytoplasm and plastids in root cells near the apical meristem. In addition, immunogold labeling detected signals from the nucleus. The immunohistochemical localization of the enzyme in the nucleus, as well as in the cytosol and plastids, indicates that lily PGAM-i might have multiple functions in the cell.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00200302
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  • 6
    Electronic Resource
    Electronic Resource
    Dielectric resonance, local field distribution, and optical response in 3D resonant composites (2004)
    Springer
    The European physical journal 42 (2004), S. 165-173 
    Details
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We extend the Green’s function formalism in a binary 2D composite to 3D. Using the formalism, we investigate the dielectric resonances, local-field distribution, and effective linear optical responses for one-bond, two-bond and three-bond clusters, as well as for various disordered composites. Due to the different values of Green’s function in 2D and 3D, for the same cluster, the values of the dielectric resonances in 3D are smaller than those in 2D, but the fields are more localized than those in 2D. The sum rule of dielectric resonance in three-component composites is extended to d dimensions. For the same resonance, the intensity of the local-field in 3D is also weaker than that in the 2D case, but the fields are more localized than those in 2D. For the disordered composites in 2D and 3D, inverse participation ratios (IPR) with q = 2 are used to represent the localization of the field. When we increase the concentration of impurity bonds, a blue shift of IPR peaks occurs in 3D, while in 2D, these peaks are very stable. Finally, both for 2D and 3D disordered composites, the absorption range broadens with increasing impurity concentration, and a red shift of the absorption peak is observed in 3D.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1140/epjb/e2004-00368-5
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  • 7
    Electronic Resource
    Electronic Resource
    Kinetics of pentachlorophenol degradation by a Flavobacterium species (1995)
    Springer
    Applied microbiology and biotechnology 43 (1995), S. 374-378 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract The kinetics of pentachlorophenol (PCP) degradation by a Flavobacterium sp. ATCC 39723 has been investigated. Sodium glutamate was supplied as an additional carbon source to increase the rate of cell growth and PCP degradation. A kinetic model including PCP toxicity for cell growth and PCP inhibition of its own degradation was developed. This model was also applied to 2,4-dichlorophenol (DCP) degradation by the same organism. Although PCP and DCP are degraded by different pathways, the model describes these two degradation processes very well.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00172842
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  • 8
    Electronic Resource
    Electronic Resource
    Kinetics of pentachlorophenol degradation by a Flavobacterium species (1995)
    Springer
    Applied microbiology and biotechnology 43 (1995), S. 374-378 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract  The kinetics of pentachlorophenol (PCP) degradation by a Flavobacterium sp. ATCC 39723 has been investigated. Sodium glutamate was supplied as an additional carbon source to increase the rate of cell growth and PCP degradation. A kinetic model including PCP toxicity for cell growth and PCP inhibition of its own degradation was developed. This model was also applied to 2,4-dichlorophenol (DCP) degradation by the same organism. Although PCP and DCP are degraded by different pathways, the model describes these two degradation processes very well.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002530050420
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  • 9
    Electronic Resource
    Electronic Resource
    Effect of laser intensity and of lower-state rotational energy transfer upon temperature measurements made with laser-induced predissociative fluorescence (1998)
    Springer
    Applied physics 66 (1998), S. 251-258 
    Details
    ISSN: 1432-0649
    Keywords: PACS: 32; 33; 42.30
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: 2 (8) and Q2(11) in OH.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003400050384
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  • 10
    Electronic Resource
    Electronic Resource
    Pressure dependence of vibrational Raman scattering of narrow-band, 248-nm, laser light by H2, N2, O2, CO2, CH4, C2H6, and C3H8 as high as 97 bar (2000)
    Springer
    Applied physics 71 (2000), S. 865-871 
    Details
    ISSN: 1432-0649
    Keywords: PACS: 33.20; 82.40; 82.80
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We have previously investigated methods that image high-pressure processes such as combustion inside automobile cylinders and aircraft engines, or chemical phenomena in supercritical fluids. Here we show that vibrational Raman scattering can simply obtain, quantitatively, densities of some combustion-relevant molecules. We use narrow-band KrF excimer-laser light. Measurements for H2, N2, O2, CO2, and CH4 are in the pressure range from 1 to 60 bar, whereas those for C2H6 and C3H8 are up to their respective vapor pressures. All these species are at ambient temperature. Additional measurements are described for CO2 up to 96.8 bar and 318 K, where CO2 is a supercritical fluid. The O2 measurements are complicated by a photochemical formation of O3; those in supercritical CO2 by drastic bending of the laser beam within this medium. We show that, for each gas, the Raman signal is directly proportional to gas density, thereby making quantitative analysis particularly convenient. For each species, we present an estimate of its Raman cross-section relative to that of N2. However we recommend that future diagnostics users calibrate their own systems for relative species sensitivity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003400000412
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