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  • Springer  (32)
  • American Chemical Society  (1)
  • 2000-2004  (33)
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  • 1
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    A perfusion-cell bleeding culture strategy for enhancing the productivity of eicosapentaenoic acid by Nitzschia laevis (2001)
    Springer
    Details
    Publication Date: 2001-10-01
    Print ISSN: 0175-7598
    Electronic ISSN: 1432-0614
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Published by Springer
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  • 2
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    Geochemical and isotopic composition and inherited zircon ages as evidence for lower crustal origin of two Variscan S-type granites in the NW Bohemian massif (2003)
    Springer
    Details
    Publication Date: 2003-03-20
    Print ISSN: 1437-3254
    Electronic ISSN: 1437-3262
    Topics: Geosciences
    Published by Springer
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  • 3
    Electronic Resource
    Electronic Resource
    Cloning and expression analysis of murine lupin, a member of a novel gene family that is conserved through evolution and associated with Lupus inclusions (2000)
    Springer
    Development genes and evolution 210 (2000), S. 512-517 
    Details
    ISSN: 1432-041X
    Keywords: Key words Systemic lupus erythematosis ; AIDS ; HIV ; p36 ; Cytoplasmic inclusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  We describe here the first full-length sequence of a member of a novel gene family encoding a protein in the mouse that we call Lupin. Lupin is homologous to a human protein previously called p36, which was purified from α-interferon-treated cells that formed lupus inclusions. Lupus inclusions are dense intracellular deposits found in endothelial cells and lymphocytes of patients with systemic lupus erythematosis and AIDS. Proteins closely related to Lupin exist in evolutionarily divergent species including Caenorhabditis elegans, Drosophila and zebrafish. At least one other lupin-related gene is expressed in the mouse and in man. Lupin is expressed in mouse embryos and adults, notably in liver, spleen, central nervous system, multiple epithelia and all types of muscle. In skeletal muscle, expression analysis suggests that Lupin associates with the contractile apparatus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004270000093
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  • 4
    Electronic Resource
    Electronic Resource
    Heterotrophic production of eicosapentaenoid acid by the diatom Nitzschia laevis: effects of silicate and glucose (2000)
    Springer
    Journal of industrial microbiology and biotechnology 25 (2000), S. 218-224 
    Details
    ISSN: 1476-5535
    Keywords: Keywords: diatom; Nitzschia laevis; EPA; glucose; silicate; heterotrophic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The effects of silicate and glucose on growth and eicosapentaenoic acid (EPA) production by the diatom Nitzschia laevis were studied. By alternately altering the concentrations of silicate (2.7–64 mg l−1) and glucose (1–40 g l−1) in the medium, the highest cell dry weight (ca. 5.5 g l−1) was obtained at 20 g l−1 glucose and 32 mg l−1 silicate, while the highest specific growth rate (ca. 0.65 day−1) was obtained at a relatively low glucose concentration (5 g l−1) and high silicate concentrations (32–64 mg l−1). At glucose levels of 5 and 20 g l−1, EPA content was higher with lower silicate concentrations (2.7 and 16 mg l−1 silicate, respectively), while at a silicate level of 16 mg l−1, higher glucose concentrations (20–40 g l−1) facilitated EPA formation. The highest EPA yield (131 mg l−1) was obtained at 20 g l−1 glucose and 32 mg l−1 silicate, while the highest EPA productivity (15.1 mg l−1 day−1) was obtained at 20 g l−1 glucose and 64 mg l−1 silicate. Journal of Industrial Microbiology & Biotechnology (2000) 25, 218–224.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/sj.jim.7000056
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  • 5
    Electronic Resource
    Electronic Resource
    Zircon ages and Nd isotopic and chemical compositions of orthogneisses from the Black Forest, Germany: evidence for a Cambrian magmatic arc (2000)
    Springer
    International journal of earth sciences 88 (2000), S. 791-802 
    Details
    ISSN: 1437-3262
    Keywords: Key words Variscan belt ; Moldanubian zone ; Black Forest ; Orthogneiss ; Zircon dating ; ¶Nd isotopes ; Geochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  Single zircon U–Pb dating combined with 207Pb/206Pb ages obtained by the evaporation method constrains the emplacement of tonalitic, trondhjemitic, and granodioritic orthogneisses of the Moldanubian zone in the Black Forest between 500 and 510 Ma. Two detrital zircon populations of 1.9 and 1.6 Ga indicate Early-Middle Proterozoic material in the former setting of the basement. The initial eNd values range from –0.1 to –3.4 and mean crustal residence ages of 1.0–1.4 Ga are consistent with involvement of Early-Middle Proterozoic crust, and a subordinate juvenile component probably originating from subduction-related melting of the mantle. The orthogneisses have fractionated REE patterns and slightly higher K2O/Na2O ratios than typical low-K tonalite–trondhjemite–granite suites. The chemical data are interpreted as evidence for melting of amphibolite and contributions from evolved crust. The emplacement of the orthogneisses was superceded by a high-temperature metamorphic event at ∼480 Ma which we interpret as a result of lithospheric thinning in a marginal basin behind a Cambrian magmatic arc.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005310050306
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  • 6
    Electronic Resource
    Electronic Resource
    Effect of yeast elicitor on the secondary metabolism of Ti-transformed Salvia miltiorrhiza cell suspension cultures (2000)
    Springer
    Plant cell reports 19 (2000), S. 710-717 
    Details
    ISSN: 1432-203X
    Keywords: Key words Salvia miltiorrhiza ; 2-Aminoindan-2-phosphonic acid ; Cryptotanshinone ; Phenylalanine ammonia-lyase ; Phytoalexin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  Salvia miltiorrhiza contains two groups of biologically active secondary metabolites termed phenolic compounds (e.g. rosmarinic acid) and tanshinones (e.g. cryptotanshinone). Their roles in plant defense responses were examined using a simplified system consisting of a yeast elicitor and a Ti C58 transformed S. miltiorrhiza cell line. Both dosage and time course studies were carried out on the effects of yeast elicitor on the formation of rosmarinic acid and cryptotanshinone. It was found that the yeast elicitor reduced the constituent level of rosmarinic acid (from ca. 5% to ca. 3.0% of dry cell weight) whereas the level of cryptotanshinone was enhanced greatly (from a negligible amount to ca. 20 mg/l). These results suggest that in S. miltiorrhiza, rosmarinic acid and cryptotanshinone may take part in plant passive and active defense responses, respectively, against pathogen attack. Cryptotanshinone was identified as a phytoalexin in S. miltiorrhiza for the first time. Results of the treatment of cell cultures with 2-aminoindan-2-phosphonic acid, a highly specific and potent inhibitor of phenylalanine ammonia-lyase (EC 4.3.1.5), indicated that this compound did not inhibit yeast elicitor induced tanshinone formation, but did inhibit rosmarinic acid biosynthesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002999900166
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  • 7
    Electronic Resource
    Electronic Resource
    Fracture toughness of ceramics and semi-brittle alloys using a miniaturized disk-bend test (2000)
    Springer
    Materials research innovations 3 (2000), S. 250-262 
    Details
    ISSN: 1433-075X
    Keywords: Key words Small-specimen testing ; Controlled-flaw method ; Fracture toughness ; Brittle materials ; Finite element analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: ∞ is the crack resistance at ”infinite” crack length. It is convincingly shown that this so-called R-curve equation correctly predicts K∞, which is comparable to the conventionally measured Mode I plain-strain fracture toughness, KIc, of the same material. The fundamental constants in the fracture-mechanics-based equations are discussed, emphasizing the aspects pertinent to the small specimens used in the MDBT. Results are presented on 8 materials: ZnS, glass-ceramic, Si3N4, Ti5Si3, SiC, Ni3Ge, NiAl and Ti-46.5A1-2.1Cr-3.0Nb-0.2W. All are brittle except for the latter two, which undergo slight plastic deformation before fracturing. The resulting values of K∞ are in excellent agreement with published values derived from conventional measurements, providing considerable confidence in the method. where Q is a constant and K∞ is the crack resistance at ”infinite” crack length. It is convincingly shown that this so-called R-curve equation correctly predicts K∞, which is comparable to the conventionally measured Mode I plain-strain fracture toughness, KIc, of the same material. The fundamental constants in the fracture-mechanics-based equations are discussed, emphasizing the aspects pertinent to the small specimens used in the MDBT. Results are presented on 8 materials: ZnS, glass-ceramic, Si3N4, Ti5Si3, SiC, Ni3Ge, NiAl and Ti-46.5A1-2.1Cr-3.0Nb-0.2W. All are brittle except for the latter two, which undergo slight plastic deformation before fracturing. The resulting values of K∞ are in excellent agreement with published values derived from conventional measurements, providing considerable confidence in the method.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00010875
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  • 8
    Electronic Resource
    Electronic Resource
    Holonic Concept Based Methodology for Part Routeing on Flexible Manufacturing Systems (2000)
    Springer
    The international journal of advanced manufacturing technology 16 (2000), S. 483-490 
    Details
    ISSN: 1433-3015
    Keywords: Keywords:Flexible manufacturing system; Simulation; Scheduling and control; Holonic concept
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A flexible manufacturing system (FMS) is designed to achieve good productivity and low cost. The success of an FMS depends largely on effective production scheduling and control. However, it has been found that current manufacturing scheduling and control algorithms lack the flexibility to handle interruptions or resource breakdowns; hence, system performance drops dramatically and abruptly when interruptions occur. This research develops a computer-simulation-based framework of FMS scheduling and control system using the holonic concept. This framework can maintain stability and flexibility while accommodating system disturbance, increase throughput, reduce part flow-time and work-in-process inventory, and balance workload among identical workstations. The significance of this research is the investigation of an innovative approach to revolutionary advances of control technologies for advanced manufacturing systems, and to the revitalisation of control and scheduling algorithms used by existing FMSs. A case study has been provided to substantiate the effectiveness of this proposed framework.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00003942
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  • 9
    Electronic Resource
    Electronic Resource
    Modulational instability on triangular dynamical lattices with long-range interactions and dispersion (2004)
    Springer
    The European physical journal 41 (2004), S. 495-501 
    Details
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. The influence of long-range interactions on the stability of stationary solutions of triangular lattices described by the continuum-discrete nonlinear Schrödinger equation is analyzed. By virtue of the linear stability analysis and a variational approach we demonstrate that both soliton array and continuous-wave solutions are modulationally unstable. Analytical expressions for instability thresholds and growth rate spectra are presented and compared with the corresponding results in the approximation of a nearest neighbor interaction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1140/epjb/e2004-00343-2
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  • 10
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    Discovery of Operational Spaces from Process Data for Production of Multiple Grades of Products (2000)
    American Chemical Society
    Details
    Publication Date: 2000-07-01
    Print ISSN: 0888-5885
    Electronic ISSN: 1520-5045
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Published by American Chemical Society
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