ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    facet.materialart.
    Unknown
    Role of lymphotoxin and the type I TNF receptor in the formation of germinal centers (1996)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1996-03-01
    Description: In mice deficient in either lymphotoxin-alpha (LT-alpha) or the type I tumor necrosis factor (TNF) receptor, but not the type II TNF receptor, germinal centers failed to develop in peripheral lymphoid organs. Germinal center formation was restored in LT-alpha-deficient mice by transplantation of normal bone marrow, indicating that the LT-alpha-expressing cells required to establish this lymphoid structure are derived from bone marrow.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Matsumoto, M -- Mariathasan, S -- Nahm, M H -- Baranyay, F -- Peschon, J J -- Chaplin, D D -- New York, N.Y. -- Science. 1996 Mar 1;271(5253):1289-91.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Immunology and Howard Hughes Medical Institute, Washington University School of Medicine, St. Louis, MO 63110, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8638112" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bone Marrow Cells ; Bone Marrow Transplantation ; Gene Targeting ; Germinal Center/cytology/immunology/*physiology ; Immunization ; Lymphotoxin-alpha/genetics/*physiology ; Mice ; Receptors, Tumor Necrosis Factor/genetics/*physiology ; Spleen/anatomy & histology/*immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 2
    facet.materialart.
    Unknown
    Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin (1994)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1994-04-29
    Description: Mice rendered deficient in lymphotoxin (LT) by gene targeting in embryonic stem cells have no morphologically detectable lymph nodes or Peyer's patches, although development of the thymus appears normal. Within the white pulp of the spleen, there is failure of normal segregation of B and T cells. Spleen and peripheral blood contain CD4+CD8- and CD4-CD8+ T cells in a normal ratio, and both T cells subsets have an apparently normal lytic function. Lymphocytes positive for immunoglobulin M are present in increased numbers in both the spleen and peripheral blood. These data suggest an essential role for LT in the normal development of peripheral lymphoid organs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉De Togni, P -- Goellner, J -- Ruddle, N H -- Streeter, P R -- Fick, A -- Mariathasan, S -- Smith, S C -- Carlson, R -- Shornick, L P -- Strauss-Schoenberger, J -- CA 16885/CA/NCI NIH HHS/ -- CA 28533/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1994 Apr 29;264(5159):703-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8171322" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; B-Lymphocytes/immunology ; Blastocyst ; Cytotoxicity, Immunologic ; Female ; Leukocyte Count ; Lymph Nodes/cytology/*growth & development/immunology ; Lymphoid Tissue/cytology/*growth & development/immunology ; Lymphotoxin-alpha/genetics/*physiology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Peyer's Patches/cytology/growth & development/immunology ; Receptors, Tumor Necrosis Factor/physiology ; Spleen/cytology/immunology ; T-Lymphocyte Subsets/immunology ; T-Lymphocytes/immunology ; Thymus Gland/cytology/immunology ; Tumor Necrosis Factor-alpha/genetics/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...