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  • 1
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    Subperiosteal expansion and cortical remodeling of the human femur and tibia with aging (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-09-03
    Description: Increases with aging in subperiosteal dimensions and second moments of area (measures of bending and torsional rigidity) in femoral and tibial cross sections are documented in an archeological sample from the American Southwest. Significant differences between cross-sectional sites and between sexes in the pattern of cortical remodeling with age are also present. These differences appear to be related to variations in the stress or strain levels in different regions of the femur and tibia which result from in vivo mechanical loadings of the lower limb.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ruff, C B -- Hayes, W C -- AM00749/AM/NIADDK NIH HHS/ -- AM26740/AM/NIADDK NIH HHS/ -- New York, N.Y. -- Science. 1982 Sep 3;217(4563):945-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7112107" target="_blank"〉PubMed〈/a〉
    Keywords: Adult ; *Aging ; Bone Development ; Female ; Femur/*physiology ; Fractures, Bone/etiology ; Growth ; Humans ; Male ; Middle Aged ; Periosteum/*physiology ; Physical Exertion ; Sex Characteristics ; Stress, Mechanical ; Tibia/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Small cell carcinoma of the lung: macrophage-specific antigens suggest hemopoietic stem cell origin (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-09-07
    Description: Four surface antigens previously recognized only in macrophages are present on human small cell lung carcinoma cells and tumors. Cancerous cells may arise from macrophage precursors in bone marrow, and these precursors migrate to lung to participate in the repair of damaged tissue produced by continuous heavy smoking. The characteristic presence of neuropeptides such as bombesin in small cell carcinoma, when considered along with these findings, presents new possibilities for the role of such peptides in nervous, endocrine, and immune system function.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ruff, M R -- Pert, C B -- New York, N.Y. -- Science. 1984 Sep 7;225(4666):1034-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6089338" target="_blank"〉PubMed〈/a〉
    Keywords: Antigens, Neoplasm/*analysis ; Antigens, Surface/*analysis ; Carcinoma, Small Cell/etiology/*immunology/pathology ; Cell Line ; Cell Transformation, Neoplastic ; *Hematopoietic Stem Cells ; Humans ; Lung Neoplasms/etiology/*immunology/pathology ; Macrophages/*immunology ; Monocytes/pathology ; Smoking
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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