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  • United States  (315)
  • American Association for the Advancement of Science (AAAS)  (315)
  • 2000-2004  (292)
  • 1980-1984  (23)
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  • American Association for the Advancement of Science (AAAS)  (315)
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Year
  • 1
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    No major schizophrenia locus detected on chromosome 1q in a large multicenter sample (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-04-27
    Description: Reports of substantial evidence for genetic linkage of schizophrenia to chromosome 1q were evaluated by genotyping 16 DNA markers across 107 centimorgans of this chromosome in a multicenter sample of 779 informative schizophrenia pedigrees. No significant evidence was observed for such linkage, nor for heterogeneity in allele sharing among the eight individual samples. Separate analyses of European-origin families, recessive models of inheritance, and families with larger numbers of affected cases also failed to produce significant evidence for linkage. If schizophrenia susceptibility genes are present on chromosome 1q, their population-wide genetic effects are likely to be small.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Levinson, Douglas F -- Holmans, Peter A -- Laurent, Claudine -- Riley, Brien -- Pulver, Ann E -- Gejman, Pablo V -- Schwab, Sibylle G -- Williams, Nigel M -- Owen, Michael J -- Wildenauer, Dieter B -- Sanders, Alan R -- Nestadt, Gerald -- Mowry, Bryan J -- Wormley, Brandon -- Bauche, Stephanie -- Soubigou, Stephane -- Ribble, Robert -- Nertney, Deborah A -- Liang, Kung Yee -- Martinolich, Laura -- Maier, Wolfgang -- Norton, Nadine -- Williams, Hywel -- Albus, Margot -- Carpenter, Eric B -- DeMarchi, Nicola -- Ewen-White, Kelly R -- Walsh, Dermot -- Jay, Maurice -- Deleuze, Jean-Francois -- O'Neill, F Anthony -- Papadimitriou, George -- Weilbaecher, Ann -- Lerer, Bernard -- O'Donovan, Michael C -- Dikeos, Dimitris -- Silverman, Jeremy M -- Kendler, Kenneth S -- Mallet, Jacques -- Crowe, Raymond R -- Walters, Marilyn -- G9309834/Medical Research Council/United Kingdom -- G9810900/Medical Research Council/United Kingdom -- K24-MH64197/MH/NIMH NIH HHS/ -- KO2-01207/PHS HHS/ -- MH 41953/MH/NIMH NIH HHS/ -- MH 45390/MH/NIMH NIH HHS/ -- MH 52537/MH/NIMH NIH HHS/ -- MH61602/MH/NIMH NIH HHS/ -- R01-MH57314/MH/NIMH NIH HHS/ -- U01 MH46289/MH/NIMH NIH HHS/ -- U01 MH46318/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 2002 Apr 26;296(5568):739-41.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA. dfl@mail.med.upenn.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11976456" target="_blank"〉PubMed〈/a〉
    Keywords: Africa ; Alleles ; Australia ; Canada ; Chromosomes, Human, Pair 1/*genetics ; Europe ; Female ; Genes, Recessive ; *Genetic Linkage ; *Genetic Predisposition to Disease ; Genotype ; Humans ; Lod Score ; Male ; Microsatellite Repeats ; Pedigree ; Schizophrenia/ethnology/*genetics ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Contribution of increasing CO2 and climate to carbon storage by ecosystems in the United States (2000)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2000-03-17
    Description: The effects of increasing carbon dioxide (CO2) and climate on net carbon storage in terrestrial ecosystems of the conterminous United States for the period 1895-1993 were modeled with new, detailed historical climate information. For the period 1980-1993, results from an ensemble of three models agree within 25%, simulating a land carbon sink from CO2 and climate effects of 0.08 gigaton of carbon per year. The best estimates of the total sink from inventory data are about three times larger, suggesting that processes such as regrowth on abandoned agricultural land or in forests harvested before 1980 have effects as large as or larger than the direct effects of CO2 and climate. The modeled sink varies by about 100% from year to year as a result of climate variability.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schimel, D -- Melillo, J -- Tian, H -- McGuire, A D -- Kicklighter, D -- Kittel, T -- Rosenbloom, N -- Running, S -- Thornton, P -- Ojima, D -- Parton, W -- Kelly, R -- Sykes, M -- Neilson, R -- Rizzo, B -- New York, N.Y. -- Science. 2000 Mar 17;287(5460):2004-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Max-Planck-Institute for Biogeochemistry, Postfach 10 01 64, D-07701 Jena, Germany. dschimel@bgc-jena.mpg.de〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10720324" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture ; Atmosphere ; Carbon/*metabolism ; Carbon Dioxide/*metabolism ; *Climate ; Computer Simulation ; *Ecosystem ; Geography ; Trees ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    More on science and politics (2003)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2003-03-01
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bass, Gary D -- Blumenthal, Paul D -- Corfman, Phil -- Darney, Philip D -- Gonsalves, Gregg -- Levin, Arthur A -- Trussell, James -- Shields, Wayne C -- New York, N.Y. -- Science. 2003 Feb 28;299(5611):1313.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12610277" target="_blank"〉PubMed〈/a〉
    Keywords: Acquired Immunodeficiency Syndrome/prevention & control ; *Advisory Committees ; Federal Government ; Humans ; *Politics ; *Public Health ; *Science ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Ecology. Ecosystem-based fishery management (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2004-07-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Pikitch, E K -- Santora, C -- Babcock, E A -- Bakun, A -- Bonfil, R -- Conover, D O -- Dayton, P -- Doukakis, P -- Fluharty, D -- Heneman, B -- Houde, E D -- Link, J -- Livingston, P A -- Mangel, M -- McAllister, M K -- Pope, J -- Sainsbury, K J -- New York, N.Y. -- Science. 2004 Jul 16;305(5682):346-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Pew Institute for Ocean Science, Rosenstiel School of Marine and Atmospheric Science (RSMAS), University of Miami, New York, NY 10022, USA. epikitch@rsmas.miami.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15256658" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Conservation of Natural Resources ; *Ecosystem ; Environment ; *Fisheries ; *Fishes ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Public health. A sound rationale needed for phase III HIV-1 vaccine trials (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2004-01-17
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Burton, Dennis R -- Desrosiers, Ronald C -- Doms, Robert W -- Feinberg, Mark B -- Gallo, Robert C -- Hahn, Beatrice -- Hoxie, James A -- Hunter, Eric -- Korber, Bette -- Landay, Alan -- Lederman, Michael M -- Lieberman, Judy -- McCune, Joseph M -- Moore, John P -- Nathanson, Neal -- Picker, Louis -- Richman, Douglas -- Rinaldo, Charles -- Stevenson, Mario -- Watkins, David I -- Wolinsky, Steven M -- Zack, Jerome A -- New York, N.Y. -- Science. 2004 Jan 16;303(5656):316.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Scripps Research Institute, La Jolla, California, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14726576" target="_blank"〉PubMed〈/a〉
    Keywords: AIDS Vaccines/*immunology ; *Clinical Trials, Phase III as Topic/economics ; Costs and Cost Analysis ; HIV Envelope Protein gp120/*immunology ; HIV Infections/*immunology/prevention & control/therapy ; HIV-1/*immunology ; Humans ; Immunization Schedule ; Immunization, Secondary ; T-Lymphocytes, Cytotoxic/immunology ; T-Lymphocytes, Helper-Inducer/immunology ; Thailand ; United States ; Vaccines, Synthetic/immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    Varshavsky's contributions (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2004-11-20
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Baumeister, Wolfgang -- Bachmair, Andreas -- Chau, Vincent -- Cohen, Robert -- Coffino, Phil -- Demartino, George -- Deshaies, Raymond -- Dohmen, Juergen -- Emr, Scott -- Finley, Daniel -- Hampton, Randy -- Hill, Christopher -- Hochstrasser, Mark -- Huber, Robert -- Jackson, Peter -- Jentsch, Stefan -- Johnson, Erica -- Kwon, Yong Tae -- Pagano, Michele -- Pickart, Cecile -- Rechsteiner, Martin -- Scheffner, Martin -- Sommer, Thomas -- Tansey, William -- Tyers, Mike -- Vierstra, Richard -- Weissman, Allan -- Wilkinson, Keith D -- Wolf, Dieter -- New York, N.Y. -- Science. 2004 Nov 19;306(5700):1290-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15550643" target="_blank"〉PubMed〈/a〉
    Keywords: History, 20th Century ; History, 21st Century ; Nobel Prize ; Proteasome Endopeptidase Complex/*metabolism ; Proteins/metabolism ; Ubiquitin/*metabolism ; Ubiquitin-Protein Ligase Complexes/genetics/*metabolism ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    Waiting for organ transplantation. Institute of Medicine Committee on Organ Transplantation (2000)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2000-02-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gibbons, R D -- Meltzer, D -- Duan, N -- New York, N.Y. -- Science. 2000 Jan 14;287(5451):237-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉University of Illinois at Chicago, Chicago, IL 60612, USA. rdgib@uic.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10660422" target="_blank"〉PubMed〈/a〉
    Keywords: *Government Regulation ; Health Policy ; Humans ; Institute of Medicine (U.S.) ; *Liver Transplantation/mortality ; *Organ Transplantation/mortality ; *Patient Selection ; *Resource Allocation ; Time Factors ; *Tissue and Organ Procurement/legislation & jurisprudence/standards ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    Biomedicine. The NASA-NCI collaboration on biomolecular sensors (2001)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2001-05-02
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Goldin, D S -- Dahl, C A -- Olsen, K L -- Ostrach, L H -- Klausner, R D -- New York, N.Y. -- Science. 2001 Apr 20;292(5516):443-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Aeronautics and Space Administration (NASA), Washington, DC 20546, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11330296" target="_blank"〉PubMed〈/a〉
    Keywords: Biomarkers ; Biomarkers, Tumor ; *Biosensing Techniques ; Miniaturization ; *National Institutes of Health (U.S.) ; *Neoplasms/diagnosis/prevention & control/therapy ; *Research ; *Space Flight ; Spacecraft ; United States ; *United States National Aeronautics and Space Administration
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Inequities in liver transplant allocation (2000)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2000-08-12
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gibbons, R D -- Duan, N -- Meltzer, D -- New York, N.Y. -- Science. 2000 Jul 28;289(5479):549-50.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10939964" target="_blank"〉PubMed〈/a〉
    Keywords: Health Policy ; Humans ; Institute of Medicine (U.S.) ; *Liver Transplantation ; *Tissue and Organ Procurement/legislation & jurisprudence ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Control of nitrogen export from watersheds by headwater streams (2001)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2001-04-09
    Description: A comparative (15)N-tracer study of nitrogen dynamics in headwater streams from biomes throughout North America demonstrates that streams exert control over nutrient exports to rivers, lakes, and estuaries. The most rapid uptake and transformation of inorganic nitrogen occurred in the smallest streams. Ammonium entering these streams was removed from the water within a few tens to hundreds of meters. Nitrate was also removed from stream water but traveled a distance 5 to 10 times as long, on average, as ammonium. Despite low ammonium concentration in stream water, nitrification rates were high, indicating that small streams are potentially important sources of atmospheric nitrous oxide. During seasons of high biological activity, the reaches of headwater streams typically export downstream less than half of the input of dissolved inorganic nitrogen from their watersheds.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Peterson, B J -- Wollheim, W M -- Mulholland, P J -- Webster, J R -- Meyer, J L -- Tank, J L -- Marti, E -- Bowden, W B -- Valett, H M -- Hershey, A E -- McDowell, W H -- Dodds, W K -- Hamilton, S K -- Gregory, S -- Morrall, D D -- New York, N.Y. -- Science. 2001 Apr 6;292(5514):86-90.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Ecosystems Center, Marine Biological Laboratory, Woods Hole, MA 02543, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11292868" target="_blank"〉PubMed〈/a〉
    Keywords: Absorption ; Animals ; Bacteria/metabolism ; Biofilms ; *Ecosystem ; Eukaryota/metabolism ; *Fresh Water ; Fungi/metabolism ; Geologic Sediments ; Nitrates/metabolism ; Nitrogen/*metabolism ; Oxidation-Reduction ; Photosynthesis ; Quaternary Ammonium Compounds/metabolism ; Seasons ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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