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  • 2015-2019
  • 1985-1989  (32)
  • 1989  (18)
  • 1988  (14)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Histochemistry and cell biology 90 (1988), S. 285-288 
    ISSN: 1432-119X
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Chronic treatment of rats with reserpine, isoproterenol, or a combination of these two agents has been suggested as a means to produce an experimental animal model for the chronic exocrinopathy cystic fibrosis. The effect of these treatments on glycoconjugate distribution in rat submandibular gland acinar cells was investigated by quantitative lectin cytochemistry. Significant changes in wheat-germ agglutinin (WGA), soy bean agglutinin (SBA) and concanavalin A (Con A) binding sites in the mucus granules were observed, but peanut agglutinin (PNA) binding was not significantly affected. The quantitative changes in glycoconjugates in the acinar cells of the submandibular gland could be a possible explanation for the increased binding of calcium by the intracellular mucus noted in previous studies on these animal models.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    European journal of clinical pharmacology 37 (1989), S. 517-520 
    ISSN: 1432-1041
    Schlagwort(e): nicotine ; epinephrine ; cigarette smoking ; total forearm blood flow ; muscle blood flow ; plethysmography
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Medizin
    Notizen: Summary In 9 healthy subjects the effect of smoking one cigarette (nicotine content 0.9 mg) on blood pressure, heart rate and total and muscle blood flow in the forearm was measured. Blood flow was measured by a new noninvasive plethysmographic method that simultaneously gives quantitative data about total and muscle blood flow. Smoking the cigarette did not significantly affect blood pressure or heart rate. Total blood flow in the forearm did not change but the flow to the muscle was increased and resistance in this vascular bed was decreased. The pattern of haemodynamic changes in the forearm indicates that epinephrine may be the mediator of the circulatory effects of nicotine.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    The European physical journal 334 (1989), S. 451-456 
    ISSN: 1434-601X
    Schlagwort(e): 12.40.Aa ; 13.75.Gx
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract The(q¯ q) creation and annihilation terms of the one-gluon-exchange Lagrangian are incorporated into the quark cluster model. A resonating group study of theπ N interaction within this extended model yields scattering phase shifts which are in qualitative agreement with experiment without any parameter adjustment.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Cellular and molecular neurobiology 8 (1988), S. 235-243 
    ISSN: 1573-6830
    Schlagwort(e): head injury ; uridine ; hypoxanthine ; xanthine ; ventriculostomy ; hydrocephalus ; lumbar spinal fluid
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary 1. Examination of the cerebrospinal fluid (CSF) of head-injured patients reveals that the concentration of intraventricular xanthine is elevated and that of uridine is decreased relative to those of adult lumbar CSF. 2. No correlations were observed between CSF lactate and CSF hypoxanthine, xanthine, or uridine, suggesting that changes in purine metabolites and the pyrimidine nucleoside do not index similar cellular events as does lactic acid production. 3. Ventricular CSF from hydrocephalic infants had uridine and hypoxanthine concentrations not significantly different from those of normal adult lumbar CSF, but xanthine was significantly elevated. 4. Since uridine has anticonvulsant properties and is a crucial substrate for cerebral metabolism, it may be useful to evaluate this pyrimidine for use in the management of patients with head injury.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Journal of thermal analysis and calorimetry 35 (1989), S. 823-835 
    ISSN: 1572-8943
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Es wird ein einfaches Modell zur umsatzkinetischen Beschreibung einer oberflächeninitiierten Kristallisation von Glaspulvern vorgestellt. Das Modell berücksichtigt die Korngröße der Glaspulver, eine konstante Verteilungsdichte von Oberflächenkristallkeimen sowie eine Temperaturerhöhung konstanter Heizrate während der Reaktion. Aus umsatzkinetischen Kurven (z. B. DTA-Kurven) von Glaspulvern unterschiedlicher Korngrößen lassen sich die Verteilungsdichte der Oberflächenkristallkeime sowie die Kristallwachstumsgeschwindigkeit abschätzen. Die Anwendungsmöglichkeiten des Modells werden am Beispiel der oberflächeninitiierten Kristallisation von Cordieritglaspulvern demonstriert.
    Kurzfassung: Резюме Предложена кинетиче ская модель поверхностно-наведе нной кристаллизации стекол. На всем протяжении ре акции учитывались ра змер зерен порошкообразных сте кол, постоянная поверхностная плотн ость зерен и постоянн ое увеличение температ уры. Скорость роста кристаллов и плотнос ть поверхности центр ов кристаллизации могу т легко установлены н а основе полных кинети ческих кривых (напр. кр ивых ДТА) порошков с различным размером зерен. Показана непри менимость такой моде ли для случая первичной пов ерхностно-наведенно й кристаллизации поро шков стеклообразног о кордерита.
    Notizen: Abstract A simple kinetic model of surface-induced glass crystallization is proposed. The grain size of glass powders, a constant density of surface nuclei and a steadily increasing temperature throughout the reaction are taken into account. The crystal growth rate and the density of surface nuclei can be estimated easily from overall kinetic curves (e.g. DTA curves) of powder of different grain size. The usefulness of the model is demonstrated in the case of the primary surface-induced crystallization of cordierite glass powders.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Journal of low temperature physics 73 (1988), S. 101-136 
    ISSN: 1573-7357
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Physik
    Notizen: Abstract The design, construction, and performance of a Cu nuclear refrigerator are reported. The first nuclear stage (total 275 moles Cu with 104 moles Cu in 8 T) has refrigerated a195Pt NMR thermometer in the low-field experimental region to 15 µK; it can keep experiments below 20 µK for more than 1 week. It can alternatively precool a second nuclear stage (2 moles Cu in 9 T). Demagnetizing this stage has resulted in a temperature of at most 12 µK as measured by another195Pt NMR thermometer attached to the stage. The details of the thermometry are described and possible origins of the observed internal heat leaks as well as unexpected contributions to the specific heat of the nuclear stages are discussed.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    Digitale Medien
    Digitale Medien
    Springer
    Mathematical methods of operations research 32 (1988), S. 213-230 
    ISSN: 1432-5217
    Schlagwort(e): linear arrangement ; dynamic programming ; NP-completeness ; Linear Arrangement ; dynamische Programmierung ; NP-Vollständigkeit
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik , Wirtschaftswissenschaften
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Wir analysieren die Komplexität von eingeschränkten Linear Arrangement Problemen, bei denen nur solche Permutationen der Knoten erlaubt sind, die durch die Ordnung eines die Knoten des Graphen strukturierenden, binären Baumes — des sogenannten P-tress — entstehen. Derartige Versionen von Linear Arrangement Problemen tauchen an mehreren Stellen in heutigen Schaltkreis Layout Systemen auf. Der P-tree resultiert dabei aus einem rekursiven Zerteiluungsprozeß des Graphen. Wir zeigen, daß das MINCUT LINEAR ARRANGEMENT und das OPTIMAL LINEAR ARRANGEMENT Problem in polynomieller Zeit lösbar sind, wenn der P-tree balanciert ist. Alle anderen betrachteten Versionen von Linear Arrangement Problemen sind NP-vollständig.
    Notizen: Abstract We analyze the complexity of the restrictions of linear arrangement problems that are obtained if the legal permutations of the nodes are restricted to those that can be obtained by orderings of a binary tree structuring the nodes of the graph, the so-called p-tree. These versions of the linear arrangement problems occur in several places in current circuit layout systems. There the p-tree is the result of a recursive partitioning process of the graph. We show that the MINCUT LINEAR ARRANGEMENT problem and the OPTIMAL LINEAR ARRANGEMENT problem can be solved in polynomial time, if the p-tree is balanced. All other versions of the linear arrangement problems we analyzed are NP-complete.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
    ISSN: 1573-6822
    Schlagwort(e): cell transformation ; cytokeratin ; cytoskeleton ; differentiation ; intermediate filaments ; nickel
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Abstract Rat liver T51 B cells were maintained in the presence of low concentrations of Ni(H) derived from αNi3S2 for 3–I5 months in culture in order to monitor cytokeratin, differentiation, and transformation patterns. Nickel exposures caused irreversible, heritable juxtanuclear aggregates of cytokeratin CKSS, which increased in size and complexity with prolonged nickel exposure, eventually resembling Mallory bodies and expressing glutamyltransferase. Altered cytokeratin expression was accompanied by induction of differentiation, with markers of both bile ductular cells and hepatocytes, such as induction of cytokeratin polypeptides CK39 and CK49, cell morphology, and cytokeratin filament network changes, whereas control cultures similarly maintained for long periods in culture remained unchanged. Altered cytokeratin expression was also accompanied by acquisition of transformation markers—loss of density dependence, progression toward calcium independence, and (benign) growth in nude mice. Observed cytokeratin aberrations may be a factor in nickel carcinogenesis, in view of the known affinity of the metal for cellular structural proteins, especially keratin, which play a role in maintenance of cell behavior.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
    Digitale Medien
    Digitale Medien
    Springer
    Fresenius' Zeitschrift für analytische Chemie 333 (1989), S. 745-746 
    ISSN: 1618-2650
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Conclusion By the use of structural analogues of nicotine and cotinine as internal standards, the elimination of environmental sources of contamination and an exact clean-up procedure, we were able to develop a rapid and sensitive method which has acceptable accuracy and precision over the concentration range necessary in pharmacokinetic studies.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
    Publikationsdatum: 1988-03-14
    Print ISSN: 0031-9007
    Digitale ISSN: 1079-7114
    Thema: Physik
    Publiziert von American Physical Society
    Standort Signatur Erwartet Verfügbarkeit
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