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  • Wiley-Blackwell  (19)
  • Nature Publishing Group  (3)
  • Oxford University Press
  • 1970-1974  (23)
  • 1970  (23)
  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 226 (1970), S. 1249-1250 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The organism was grown in 500 ml. of modified medium No. 2 of Gledhill and Casida1casein hydrolysate (Oxoid) substituted for casamino-acids (Difco)in 2 1. flasks incubated at 30 C for 7 days. Cells were centrifuged, washed in 0.025 M phosphate buffer (pH. 7.4), then resus-pended in the same buffer ...
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 228 (1970), S. 464-465 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Recent observations indicate that other endocrine glands are concerned in cholesterol metabolism. We have demonstrated4 that pituitary growth hormone is important in normal cholesterol metabolism in the rat. Because the secretion of growth hormone soon ceases in the absence of circulating thyroid ...
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  • 3
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 225 (1970), S. 464-467 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] To determine whether the hypereholesterolaemia occurring in the hypophysectomized rat was solely the result of impaired thyroid function, we first measured the serum cholesterol changes taking place in five groups of ten mature male rats (Long Evans strain) after (a) simple thyroidectomy (T), (6) ...
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 103 (1970), S. 1792-1796 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Glycosides of Amino Sugars, II. Synthesis of 2-amino-2-deoxy-α-D-glucopyranosidesThe synthesis of glycosides and disaccharides of 2-amino-2-deoxy-D-glucose has been explored using trifluoroacetyl as the N-blocking group. Because of its high tendency for neighboring group participation only β-D-glycosides were formed. The corresponding α-disaccharide could be obtained as the main product when employing 2.4-dinitrophenyl as the N-protecting group.
    Notes: Die N-Trifluoracetyl-Schutzgruppe wurde zur Synthese von Glykosiden und Disacchariden der 2-Amino-2-desoxy-D-glucose benutzt. Sie zeigte eine hohe Tendenz zur Nachbargruppen-beteiligung unter Bildung von -β-D-Glykosiden. Das entsprechende α-Disaccharid wurde als Hauptprodukt bei Verwendung der N-2.4-Dinitrophenyl-Schutzgruppe erhalten.
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 103 (1970), S. 2424-2427 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Di- and Polyamino Sugars, XV. XIV. Mitteil.: W. Meyer zu Reckendorf, Tetrahedron Letters [London] 1970, 287. Synthese der 2.4-Diamino-1.6-anhydro-2.4-dideoxy-D-talose. Synthesis of 2,4-Diamino-1,6-anhydro-2,4-dideoxy-D-taloseDehydrogenation of the amino reductone 1 with iodine yields a triulose which is isolated as the phenylhydrazone-phenylazo derivative 2. Spontaneous cyclization of 2 forms the 1.6-anhydro compound 3. On hydrogenation 2as well as 3are transformed into the title compound.
    Notes: Die durch Dehydrierung des Aminoreduktons 1 mit Jod entstehende Triulose wird als Bis-phenylhydrazon 2 isoliert, das die Konstitution eines Phenylhydrazon-benzolazo-Derivates besitzt. 2 cyclisiert leicht zur 1.6-Anhydro-Verbindung 3, die, wie auch 2, bei der katalytischen Hydrierung die Titelverbindung liefert.
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 103 (1970), S. 2084-2090 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Condensations of Cyclic Aryl-conjugated α-Bromoketones with FormaldehydeReactions of carbocyclic and heterocyclic α-bromoketones with formaldehyde yield α-epoxy-α-methylketones or α, β-unsaturated α-(hydroxymethyl)ketones.
    Notes: Die Umsetzung einer Reihe von carbocyclischen und heterocyclischen α-Brom-ketonen mit Formaldehyd ergibt α-Epoxy-α-methyl-ketone oder α. β-ungesättigte α-Hydroxymethyl-ketone.
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  • 7
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 103 (1970), S. 863-867 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Compounds with Urotropin Structure, XLVII. A New Syntheses of 1,2 - and 2, 6-Disubstituted Adamantanes
    Notes: Kondensation des Pyrrolidin-Enamins von Cyclohexanon-(4)-carbonsäure-(1)-äthylester (1) mit 2-Brommethyl-acrylsäureester liefert Adamantandion-(2.6)-carbonsäure-(1)-äthylester (2). Durch selective Reduktion der Carbonylgruppe in 6-Stellung entsteht aus 2 Adamantanon (2)carbonsäure-(1)-äthylester (7). 1-Brom-adamantandion-(2.6) (8) ist durch Silbersalzabbau der aus 2 erhaltenen Säure 5 zugänglich. Aus der Bromverbindung ist durch Reduktion Adamantandion-(2.6) (12) und durch Favorski-Reaktion Noradamantanon-(4)-carbonsäure-(1) (10) erhältlich.Condensation of the pyrrolidine enamine of ethyl 4-oxocyclohexane-1-carboxylate (1) with ethyl 2-(bromomethyl) acrylate yielded ethyl 2.6-dioxoadamantane-1-carboxylate (2). Selective reduction of the carbonyl group at the 6-position in 2 leads to ethyl 2-oxoadamantane-1-carboxylate (7). 1-Bromo-2.6-dioxoadamantane (8) is accessible by silver salt degradation of the acid 5 obtained from 2. The bromo compound is reduced to 2.6-dioxoadamantane (12) and undergoes the favorski reaction to yield 4-oxonoradamantane-1-carboxylic acid (10).
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  • 8
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 103 (1970), S. 995-996 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
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  • 9
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 103 (1970), S. 2418-2423 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Elimination Reactions of a Pyranose Enolacetate. A Pyranose Amino ReductoneThe α-azidoketone 1 is easily transformed either directly or via the enolacetate 2 into the vinylogous amide 4 which on acid treatment yields 8. 4 and 8 show the typical reactions of reductones. On reduction 8 yields derivatives of 2-amino-2-deoxy-D-allose only.
    Notes: Das α-Azido-keton 1 geht leicht direkt oder über das Enolacetat 2 in das vinyloge Säureamid 4 über, Aus dem mit Säure 8 entsteht. 4 und 8 zeigen die typischen Reaktionen von Reduktonen. Bei der Reduktion gibt 8 ausschließlich Derivate der 2-Amino-2-desoxy-D-allose.
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  • 10
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Berichte der deutschen chemischen Gesellschaft 103 (1970), S. 37-45 
    ISSN: 0009-2940
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Synthesis of 2.3-Diamino-2.3-dideoxy-D-galactoseThe title compound is synthesized by inversion of configuration at C-4 in suitably substituted derivatives of 2,3-diamino-2,3-dideoxy-D-glucose (6 and 7). The 4-mesyloxy group shows a very high reactivity in these compounds due to the neighboring benzamido group at C-3. Reaction with sodium acetate causes cyclization to an oxazoline which on ring opening gives the corresponding galacto derivatives. On reaction with alkoxides attack by the nitrogen atom seems to be preferred giving cyclization products of partly unknown constitution.
    Notes: Die Darstellung der Titelverbindung erfolgt durch Inversion der Konfiguration von C-4 in geeignet substituierten Derivaten der 2.3-Diamino-2.3-didesoxy-D-glucose (6 und 7). Die 4-Mesyloxygruppe zeigt in diesen Verbindungen eine sehr hohe Reaktionsfähigkeit, bedingt durch die Nachbarschaft der Benzamidgruppe an C-3. Während Umsetzung mit Natrium-acetat Cyclisierung zu einem Oxazolin bewirkt, welches bei der Ringöffnung in das entsprechende galakto-Derivat übergeht, führt die Reaktion mit Alkoholaten zu Cyclisierungs-produkten, die durch Beteiligung des N-Atoms entstehen und deren Konstitution zum Teil noch nicht aufgeklärt werden konnte.
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