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  • English  (42)
  • 1
    Publication Date: 2023-03-07
    Description: Background: Diarrhoeal disease is a leading cause of childhood illness and death globally, and Shigella is a major aetiological contributor for which a vaccine might soon be available. The primary objective of this study was to model the spatiotemporal variation in paediatric Shigella infection and map its predicted prevalence across low-income and middle-income countries (LMICs). - Methods: Individual participant data for Shigella positivity in stool samples were sourced from multiple LMIC-based studies of children aged 59 months or younger. Covariates included household-level and participant-level factors ascertained by study investigators and environmental and hydrometeorological variables extracted from various data products at georeferenced child locations. Multivariate models were fitted and prevalence predictions obtained by syndrome and age stratum. - Findings: 20 studies from 23 countries (including locations in Central America and South America, sub-Saharan Africa, and south and southeast Asia) contributed 66 563 sample results. Age, symptom status, and study design contributed most to model performance followed by temperature, wind speed, relative humidity, and soil moisture. Probability of Shigella infection exceeded 20% when both precipitation and soil moisture were above average and had a 43% peak in uncomplicated diarrhoea cases at 33°C temperatures, above which it decreased. Compared with unimproved sanitation, improved sanitation decreased the odds of Shigella infection by 19% (odds ratio [OR]=0·81 [95% CI 0·76–0·86]) and open defecation decreased them by 18% (OR=0·82 [0·76–0·88]). - Interpretation: The distribution of Shigella is more sensitive to climatological factors, such as temperature, than previously recognised. Conditions in much of sub-Saharan Africa are particularly propitious for Shigella transmission, although hotspots also occur in South America and Central America, the Ganges–Brahmaputra Delta, and the island of New Guinea. These findings can inform prioritisation of populations for future vaccine trials and campaigns.
    Language: English
    Type: info:eu-repo/semantics/article
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  • 2
    Publication Date: 2023-04-18
    Language: English
    Type: info:eu-repo/semantics/article
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  • 3
    Publication Date: 2023-07-27
    Description: We summarise the discussions at a virtual Community Workshop on Cold Atoms in Space concerning the status of cold atom technologies, the prospective scientific and societal opportunities offered by their deployment in space, and the developments needed before cold atoms could be operated in space. The cold atom technologies discussed include atomic clocks, quantum gravimeters and accelerometers, and atom interferometers. Prospective applications include metrology, geodesy and measurement of terrestrial mass change due to, e.g., climate change, and fundamental science experiments such as tests of the equivalence principle, searches for dark matter, measurements of gravitational waves and tests of quantum mechanics. We review the current status of cold atom technologies and outline the requirements for their space qualification, including the development paths and the corresponding technical milestones, and identifying possible pathfinder missions to pave the way for missions to exploit the full potential of cold atoms in space. Finally, we present a first draft of a possible road-map for achieving these goals, that we propose for discussion by the interested cold atom, Earth Observation, fundamental physics and other prospective scientific user communities, together with the European Space Agency (ESA) and national space and research funding agencies.
    Language: English
    Type: info:eu-repo/semantics/article
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  • 4
    Publication Date: 2023-08-31
    Description: Extensive efforts have been dedicated to deciphering the interactions associated with Sustainable Development Goals (SDGs). However, these developments are hampered by a lack of efficient strategies to avoid beneficial synergies being offset by harmful trade-offs. To fill these gaps, we used causal diagnosis and network analysis methods to construct 1302 directed networks of SDGs for 31 provinces in China from 2000 to 2020. We observed a dramatic offsetting effect of SDG synergies and trade-offs in China from 2000 to 2020, with approximately 27% of trade-off indicator pairs turning into synergies and about 25% of the synergy indicator pairs turning into trade-offs. However, our findings suggested that prioritising the progress of high-frequency indicators in virtuous cycles could multiply the positive systemic effects of the SDGs. Moreover, controlling the transition from passive to active in the trade-off network of SDGs remains a challenge in advancing the SDGs holistically.
    Language: English
    Type: info:eu-repo/semantics/article
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  • 5
    Publication Date: 2024-04-18
    Description: Climate models are vital for understanding and projecting global climate change and its associated impacts. However, these models suffer from biases that limit their accuracy in historical simulations and the trustworthiness of future projections. Addressing these challenges requires addressing internal variability, hindering the direct alignment between model simulations and observations, and thwarting conventional supervised learning methods. Here, we employ an unsupervised Cycle-consistent Generative Adversarial Network (CycleGAN), to correct daily Sea Surface Temperature (SST) simulations from the Community Earth System Model 2 (CESM2). Our results reveal that the CycleGAN not only corrects climatological biases but also improves the simulation of major dynamic modes including the El Niño-Southern Oscillation (ENSO) and the Indian Ocean Dipole mode, as well as SST extremes. Notably, it substantially corrects climatological SST biases, decreasing the globally averaged Root-Mean-Square Error (RMSE) by 58%. Intriguingly, the CycleGAN effectively addresses the well-known excessive westward bias in ENSO SST anomalies, a common issue in climate models that traditional methods, like quantile mapping, struggle to rectify. Additionally, it substantially improves the simulation of SST extremes, raising the pattern correlation coefficient (PCC) from 0.56 to 0.88 and lowering the RMSE from 0.5 to 0.32. This enhancement is attributed to better representations of interannual, intraseasonal, and synoptic scales variabilities. Our study offers a novel approach to correct global SST simulations and underscores its effectiveness across different time scales and primary dynamical modes.
    Language: English
    Type: info:eu-repo/semantics/article
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  • 6
    Publication Date: 2020-12-08
    Description: The convergence between the Indian and Eurasian plates has produced the thick crust and uplifted the Tibetan plateau since about 50 Ma. However, the deformation of the mantle lithosphere is still a puzzle. The geometry of the subducting Indian mantle lithosphere beneath the plateau and the thickening or/and delamination of the Tibetan mantle lithosphere are the keys for understanding the continental collision process and the evolution of the plateau. However, knowledge has been restricted due to sparse data coverage in Tibet. In this study, S-wave receiver functions are calculated using tele-seismic waveforms recorded by two broadband arrays in central Tibet to image the lithospheric structure, mainly the depth variation of the lithosphere-asthenosphere boundary (LAB). Our results show that the depth of the Tibetan LAB decreases from ∼150 km in the west to ∼120 km in the east across the north-south trending Yadong-Gulu rift. Similarly, the LAB depth of the subducting Indian slab decreases from ∼270 km in the west to ∼200 km in the east, and the northernmost subducting Indian slab can be observed beneath the Bangong-Nujiang suture. These observations suggest that the thickness of the Tibetan lithosphere and the depth of the underlying Indian slab are segmented across the Yadong-Gulu rift in different degrees. The abrupt changes imply that the subducting Indian slab has been torn, which provided an upwelling channel for the asthenosphere contributing to the development of the rift.
    Language: English
    Type: info:eu-repo/semantics/article
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  • 7
    Publication Date: 2023-01-18
    Description: Starting in 2016, the Taroko Earth Surface Observatory (TESO), a catchment-wide geomorphic observatory was set up in the Liwu catchment in the Taroko National Park in Taiwan. The set up consists of two basic station types: combined seismic and weather stations, featuring a broadband seismometer logging and a multi-parameter weather sensor, and hydrometric stations, the instrumentation of which are specific at each location. Seismic data hosted by the GEOFON database is openly accessible in real time.
    Language: English
    Type: info:eu-repo/semantics/workingPaper
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  • 8
    Publication Date: 2023-01-28
    Description: The Bransfield Basin is a young (∼4 Ma) back-arc basin related to the remnant subduction of the Phoenix Plate that once existed along the entire Pacific margin of the Antarctic Peninsula. Based on a recently deployed amphibious seismic network, we use ambient noise tomography to obtain the S-wave velocity structure in the Central Bransfield Basin (CBB). Combining with the stress-field inverted from focal mechanisms, our images reveal that the CBB suffers a significant extension in the northwest-southeast direction. The extension is strongest in the northeastern CBB with associated mantle exhumation and weakens to the southwest with decoupled deformations between the upper crust and lithospheric mantle. Such an along-strike variation of extension can be explained by slab window formation and forearc rotation, which are associated with the Phoenix Plate detachment during the ridge–trench collisions at the southwest of the Hero Fracture Zone.
    Language: English
    Type: info:eu-repo/semantics/article
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  • 9
    Publication Date: 2020-02-12
    Language: English
    Type: info:eu-repo/semantics/conferenceObject
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  • 10
    Publication Date: 2020-02-12
    Description: Based on passive seismic interferometry applied to ambient seismic noise recordings between station pairs belonging to a small-scale array, we have obtained shear wave velocity images of the uppermost materials that make up the Dead Sea Basin. We extracted empirical Green’s functions from cross-correlations of long-term recordings of continuous data, and measured inter-station Rayleigh wave group velocities from the daily correlation functions for positive and negative correlation time lags in the 0.1–0.5 Hz bandwidth. A tomographic inversion of the travel times estimated for each frequency is performed, allowing the laterally varying 3-D surface wave velocity structure below the array to be retrieved. Subsequently, the velocity-frequency curves are inverted to obtain S-wave velocity images of the study area as horizontal depth sections and longitude- and latitude-depth sections. The results, which are consistent with other previous ones, provide clear images of the local seismic velocity structure of the basin. Low shear velocities are dominant at shallow depths above 3.5 km, but even so a spit of land with a depth that does not exceed 4 km is identified as a salt diapir separating the low velocities associated with sedimentary infill on both sides of the Lisan Peninsula. The lack of low speeds at the sampling depth of 11.5 km implies that there are no sediments and therefore that the basement is near 10–11 km depth, but gradually decreasing from south to north. The results also highlight the bowl-shaped basin with poorly consolidated sedimentary materials accumulated in the central part of the basin. The structure of the western margin of the basin evidences a certain asymmetry both whether it is compared to the eastern margin and it is observed in north–south direction. Infill materials down to ∼8 km depth are observed in the hollow of the basin, unlike what happens in the north and south where they are spread beyond the western Dead Sea shore.
    Keywords: 550 - Earth sciences
    Language: English
    Type: info:eu-repo/semantics/article
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