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  • 1
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    Characterization of Landau subbands in graphite: A tight-binding study (2011)
    American Physical Society (APS)
    Details
    Publication Date: 2011-03-09
    Description: Author(s): Y. H. Ho, J. Wang, Y. H. Chiu, M. F. Lin, and W. P. Su A tight-binding model is diagonalized to elucidate the magnetoelectronic properties of bulk graphite. This method reveals far more significant results than previous treatments based on simplified effective-mass approximation. The wave functions are explicitly presented and their spatial distribution... [Phys. Rev. B 83, 121201] Published Tue Mar 08, 2011
    Keywords: Semiconductors I: bulk
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 2
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    Influence of modulated fields on the Landau level properties of graphene (2011)
    American Physical Society (APS)
    Details
    Publication Date: 2011-05-04
    Description: Author(s): Y. C. Ou, J. K. Sheu, Y. H. Chiu, R. B. Chen, and M. F. Lin The influences of modulated electric fields and modulated magnetic fields on low-energy Landau levels (LL’s) of monolayer graphene are investigated by the tight-binding model. The ratio of the uniform magnetic-field strength to the modulated field strength is arbitrarily chosen for discussions. Bo... [Phys. Rev. B 83, 195405] Published Tue May 03, 2011
    Keywords: Surface physics, nanoscale physics, low-dimensional systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 3
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    NextGen Voices: Quality mentoring (2018)
    American Association for the Advancement of Science (AAAS)
    In: Science
    Details
    Publication Date: 2018-10-05
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Geosciences , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Unexpected link between an antibiotic, pannexin channels and apoptosis (2014)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2014-03-22
    Description: Plasma membrane pannexin 1 channels (PANX1) release nucleotide find-me signals from apoptotic cells to attract phagocytes. Here we show that the quinolone antibiotic trovafloxacin is a novel PANX1 inhibitor, by using a small-molecule screen. Although quinolones are widely used to treat bacterial infections, some quinolones have unexplained side effects, including deaths among children. PANX1 is a direct target of trovafloxacin at drug concentrations seen in human plasma, and its inhibition led to dysregulated fragmentation of apoptotic cells. Genetic loss of PANX1 phenocopied trovafloxacin effects, revealing a non-redundant role for pannexin channels in regulating cellular disassembly during apoptosis. Increase in drug-resistant bacteria worldwide and the dearth of new antibiotics is a major human health challenge. Comparing different quinolone antibiotics suggests that certain structural features may contribute to PANX1 blockade. These data identify a novel linkage between an antibiotic, pannexin channels and cellular integrity, and suggest that re-engineering certain quinolones might help develop newer antibacterials.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078991/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078991/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Poon, Ivan K H -- Chiu, Yu-Hsin -- Armstrong, Allison J -- Kinchen, Jason M -- Juncadella, Ignacio J -- Bayliss, Douglas A -- Ravichandran, Kodi S -- 107848/PHS HHS/ -- R01 GM064709/GM/NIGMS NIH HHS/ -- R01 GM107848/GM/NIGMS NIH HHS/ -- T32 AI007496/AI/NIAID NIH HHS/ -- England -- Nature. 2014 Mar 20;507(7492):329-34. doi: 10.1038/nature13147. Epub 2014 Mar 12.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉1] The Center for Cell Clearance, University of Virginia, Charlottesville, Virginia 22908, USA [2] Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia 22908, USA [3] Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, Virginia 22908, USA [4] La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia. ; Department of Pharmacology, University of Virginia, Charlottesville, Virginia 22908, USA. ; 1] The Center for Cell Clearance, University of Virginia, Charlottesville, Virginia 22908, USA [2] Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia 22908, USA [3] Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, Virginia 22908, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24646995" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Anti-Bacterial Agents/*adverse effects/blood/*pharmacology ; Apoptosis/*drug effects ; Connexins/*antagonists & inhibitors/deficiency/genetics/metabolism ; Drug Discovery/methods ; Female ; Fluoroquinolones/*adverse effects/blood/*pharmacology ; Humans ; Jurkat Cells ; Male ; Mice ; Mice, Inbred C57BL ; Naphthyridines/*adverse effects/blood/*pharmacology ; Nerve Tissue Proteins/*antagonists & inhibitors/deficiency/genetics/metabolism ; Thymocytes/cytology/drug effects/metabolism
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 5
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    Flexible ferroelectric element based on van der Waals heteroepitaxy (2017)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2017-06-10
    Description: We present a promising technology for nonvolatile flexible electronic devices: A direct fabrication of epitaxial lead zirconium titanate (PZT) on flexible mica substrate via van der Waals epitaxy. These single-crystalline flexible ferroelectric PZT films not only retain their performance, reliability, and thermal stability comparable to those on rigid counterparts in tests of nonvolatile memory elements but also exhibit remarkable mechanical properties with robust operation in bent states (bending radii down to 2.5 mm) and cycling tests (1000 times). This study marks the technological advancement toward realizing much-awaited flexible yet single-crystalline nonvolatile electronic devices for the design and development of flexible, lightweight, and next-generation smart devices with potential applications in electronics, robotics, automotive, health care, industrial, and military systems.
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Progressive failure of composite wind blades with a shear-web spar subjected to static testing (2017)
    Institute of Physics (IOP)
    Details
    Publication Date: 2017-06-28
    Description: Composite wind blades of 1m long comprising glass-fabric/epoxy skins and a sandwich plate-type spar were designed and fabricated for static testing. In the composite wind blades, the spar supports the top and bottom skins to form the airfoil shape of NACA4418. The blades were tested to failure and the failure modes were identified at different loading stages. A structural failure analysis method which consists of a geometrically nonlinear finite element (FE) model and appropriate phenomenological failure criteria is used to study the progressive failure behaviours of the blades subjected to different types of quasi-static loads. The experimental load-displacement curves as well as failure loads and locations for different failure modes are used to validate the suitability of the proposed failure analysis method.
    Print ISSN: 1757-8981
    Electronic ISSN: 1757-899X
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Published by Institute of Physics (IOP)
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  • 7
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    Emergent Conformal Symmetry and Geometric Transport Properties of Quantum Hall States on Singular Surfaces (2016)
    American Physical Society (APS)
    Details
    Publication Date: 2016-12-28
    Description: Author(s): T. Can, Y. H. Chiu, M. Laskin, and P. Wiegmann We study quantum Hall states on surfaces with conical singularities. We show that the electronic fluid at the cone tip possesses an intrinsic angular momentum, which is due solely to the gravitational anomaly. We also show that quantum Hall states behave as conformal primaries near singular points, … [Phys. Rev. Lett. 117, 266803] Published Thu Dec 22, 2016
    Keywords: Condensed Matter: Electronic Properties, etc.
    Print ISSN: 0031-9007
    Electronic ISSN: 1079-7114
    Topics: Physics
    Published by American Physical Society (APS)
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  • 8
    Electronic Resource
    Electronic Resource
    Determination of photofragment ion translational energy and angular distributions in an octopole ion guide: A case study of the Ar2+ and (N2O⋅H2O)+ cluster ions (1998)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 109 (1998), S. 7450-7461 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The first measurement of ion photodissociation product recoil velocity and angular anisotropy in an octopole ion guide are presented. The experimental and numerical procedures required to obtain photofragment ion translational energy and angular distributions are discussed. Cluster ions are photodissociated in an octopole ion guide, and photofragment ion velocity distributions are measured using time-of-flight (TOF). The instrumental discrimination function is determined using guiding field variation (VAR). A validation study using the 2Σg+←2Σu+ transition of Ar2+ probed at 300 nm and a photodissociation dynamics study of (N2O⋅H2O)+ to form N2OH++OH, N2O++H2O, and H2O++N2O in the 458–657 nm range are presented. The H2O+ and N2O+ photofragment translational energy and angular distributions are derived, and new information regarding the photodissociation of the (N2O⋅H2O)+ cluster ion is obtained. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.477367
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  • 9
    Electronic Resource
    Electronic Resource
    Deuterium isotope effects in collision-induced dissociation and photodissociation of the (N2O,H2O)+ cluster ion (1998)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 108 (1998), S. 9383-9389 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We present low energy collision-induced dissociation (CID) and visible photodissociation (PD) data of jet-cooled (N2O,H2O/D2O)+ cluster ions. The same three fragment ions are observed in both CID and PD, namely, H2O+/D2O+, N2O+, and N2OH+/N2OD+. The H2O+ and N2O+ product channels exhibit a small deuterium isotope effect in both CID (10%) and PD (15%). The N2OH+ product channel, on the other hand, exhibits a much larger deuterium isotope effect for CID (30%) and PD (230%). The large difference in deuterium isotope effects observed in the N2OH+ product channel for CID and PD suggests that this product is formed via collision-induced and photoinduced proton-transfer reactions. These results are consistent with the interpretation that a single isomeric form, namely a (N2O⋅H2O)+ association complex, predominates. No evidence is found supporting the existence of a proton-transfer complex, i.e., N2OH+⋅OH. Evidence for the formation of minor amounts of a weakly bound isomeric form with the charge localized on the H2O moiety, i.e., N2O⋅H2O+, is found. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.475339
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  • 10
    Electronic Resource
    Electronic Resource
    Replacement of soybean (Glycine max (L.) Merrill) meal by lupin (Lupinus angustifolius) seed meal in diet for juvenile tilapia (Oreochromis niloticus×O. aureus) reared indoors (2003)
    Oxford, UK : Blackwell Science Ltd
    Aquaculture research 34 (2003), S. 0 
    Details
    ISSN: 1365-2109
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: An 8-week trial was conducted to assess the feasibility of replacing soybean meal (SBM) by lupin seed meal (LSM) in simulated commercial diets for juvenile tilapia starting at 0.3 g. Of the dietary protein (26% crude protein), 3.45% was from fishmeal and the rest came from the vegetable protein sources. The protein source of the control (C) diet came mainly from SBM and none (0%) from LSM. For the other diets, 33%, 67%, or 100% of the SBM protein was replaced by protein from either whole or dehulled LSM. One further diet was used: AW100, where alkaloid of the whole lupin seed was reduced. Survival, growth, and feed performance were compared among seven orthogonal contrasts to determine the effects of replacing SBM with whole LSM or dehulled LSM, and of reducing the alkaloid content. No differences in survival were found among all contrasts. No differences in fish growth and feed performance were found between feeding diet C and the other six diets ((whole, dehulled) × (33, 67, and 100)). Dehulled LSM diets resulted in better growth and feed performance than the whole LSM diets. Partial replacement of SBM by either dehulled LSM or whole LSM in diets obtained better growth and feed performance than total replacement. The AW100 diet resulted in equal fish growth but better feed performance than the W100 diet. This study concluded that partial, but not total, replacement of soybean protein with lupin seed protein in juvenile tilapia diets resulted in better, or at least equal, growth and feed performance. Dehulling further enhanced the growth and performance of LSM. Alkaloid removal improved feed performance but not the growth.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2109.2003.00935.x
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