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    Electrochemical interactions at the endothelial surface (1973)
    Wiley
    Details
    Publication Date: 1973-01-01
    Print ISSN: 0091-7419
    Electronic ISSN: 1547-9366
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Published by Wiley
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    PAPER CURRENT
  • 2
    Electronic Resource
    Electronic Resource
    Electrochemical interactions at the endothelial surface (1973)
    New York, N.Y. : Wiley-Blackwell
    Journal of Supramolecular Structure 1 (1973), S. 417-436 
    Details
    ISSN: 0091-7419
    Keywords: Life Sciences ; Molecular Cell Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jss.400010420
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    In vitro and in vivo evaluations of dacron velour and knit prostheses (1979)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 13 (1979), S. 937-956 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Dacron velour and knit prostheses were compared with respect to long-term patency when used as canine aortic implants. These grafts were rated, according to the average numerical value of six equally weighted criteria, in decreasing order of performance: velour I, velour II, circular knit III, velour IV, circular knit V, warp-knit VI, warp-knit VII and VIII, warp-knit IX and warp-knit X. In general, compacting and crimping methods using halogenated hydrocarbons produced the least successful grafts. Grafts of identical brand but compacted and crimped by different methods exhibited different patencies. No true healing of any of the grafts was observed. Layered deposits of inner fibrous capsule were formed at rates and thicknesses c a acteristic for each type of graft employed. A functioning Dacron femoral-popliteal bypass removed from a human after 9 months exhibited inner and outer fibrous capsules similar to those from canine implants.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820130611
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  • 4
    Electronic Resource
    Electronic Resource
    Antithrombogenic characteristics of cathodically polarized copper prostheses (1972)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 6 (1972), S. 489-498 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: In previous studies from our laboratories, it was shown that metals and alloys which register negative potentials in blood vs. the normal hydrogen electrode (NHE) tend to be antithrombogenic, while those with positive potentials are invariably thrombogenic. Of the metals, only the corrodible ones fall in the first group and the noble ones in the second. Blood compatible metals appear to be essential for some types of medical devices. This paper deals with a novel approach of maintaining an implanted metallic prostheses at a negative potential. A copper vascular prostheses in a dog was made the cathode in a polarizing circuit, which in addition consists of a smal mercury battery, a resistor and an auxiliary electrode. Such experiments were conducted in three animals, and the potentials ranged from -60 to -160 mV/NHE. The three dogs were sacrificed after 6, 8, and 14 days and the tubes were examined. All tubes were free of thrombus deposits; minimal junctional thrombi were found. Two copper tubes with no polarizing circuit and registering positive potentials were occluded after 8 and 14 days, respectively. Histologic and electron-microscopic studies of the thrombus deposits in tubes at spontaneous potentials and of the junctional thrombus deposits in the tube at negative potentials showed similar structures. The present experiments further confirm the view that the potential across the conductive material-blood interface is a more basic parameter than the chemical nature of the surface in determining its blood-compatible characteristic.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820060603
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  • 5
    Electronic Resource
    Electronic Resource
    Thromboresistance of glass after glow discharge treatment in argon (1975)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 9 (1975), S. 547-560 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Glow discharge treated (GDT) inorganic materials are sterile and free of all organic contaminants. Such materials implanted in the canine inferior vena cava often demonstrate significant thromboresistance. Standard Pyrex glass tubing was GDT in argon to provide a surface free energy above 70 dynes/cm, slight surface negativity, and other surface-physical modifications of its interface. Chromic acid cleaned lengths of the same tubing, and short segments whose edges were not fire-polished were used as controls. Upon canine implantation, the in vivo results were similar in independent surgical laboratories. The glass was implanted as 1.4 cm long rings or as 5 cm long tubes in separate medical centers according to different protocols. GDT specimens remained patent; all controls accumulated thrombi. A remarkably pure, low critical surface tension, labile protein coating covered all cylindrical lumens after 2 hr in vivo. This coating diminished within 2 weeks and was essentially absent after 480 days, even though scanning EM showed evidence of a micron thick luminal film, probably eroding glass. No emboli were found in the implant animal's kidney or lungs at any stage.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820090603
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  • 6
    Electronic Resource
    Electronic Resource
    A clinical experience with the NCGT graft (1981)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 15 (1981), S. 335-341 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: A comparison of 130 grafts done in 101 patients included 47 veins, 25 Johnson & Johnson dialdehyde-starch-tanned collagen prostheses, and 58 NCGT grafts that had been followed for a 40-month period. This study had documented the fact that in spite of frequent poor runoff, a useful result is provided by the NCGT graft apparently due in part to its built-in nonthrombogenic structure providing a cumulative patency of 73%. The patency rate was even superior with venous bypasses. Therefore, we still feel that the autogenous vein provides the most useful bypass conduit available in vascular reconstruction. In situations where a vein could not be used or was not available the NCGT graft offers an equally useful nonthrombogenic surface to maintain prolonged patency. Thus, collagen appropriately modified can provide a useful prosthesis in vascular reconstruction.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820150305
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