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  • 1
    Monograph available for loan
    Monograph available for loan
    Resampling methods for dependent data (2003)
    New York [u.a.] : Springer
    Associated volumes
    Details Availability
    Call number: PIK M 311-09-0038
    In: Springer series in statistics
    Description / Table of Contents: Contents: 1 Scope of Bootstrap Methods for Dependent Data ; 2 Bootstrap Methods ; 3 Properties of Block Bootstrap Methods for the Sample Mean ; 4 Extensions and Examples ; 5 Comparison of Block Bootstrap Methods ; 6 Second Order Properties ; 7 Empirical Choice of the Block Size ; 8 Model Based Bootstrap ; 9 Frequency Domain Bootstrap ; 10 Long Range Dependence ; 11 Bootstrapping Heavy-tailed Data and Extremes ; 12 Resampling Methods for Spatial Data ; Appendix A ; Appendix B
    Type of Medium: Monograph available for loan
    Pages: XIV, 374 S. : graph. Darst.
    ISBN: 0387009280
    Series Statement: Springer series in statistics
    Location: A 18 - must be ordered
    Branch Library: PIK Library
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  • 2
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    Molecularly resolved label-free sensing of single nucleobase mismatches by interfacial LNA probes (2016)
    Oxford University Press
    Details
    Publication Date: 2016-05-06
    Description: So far, there has been no report on molecularly resolved discrimination of single nucleobase mismatches using surface-confined single stranded locked nucleic acid (ssLNA) probes. Herein, it is exemplified using a label-independent force-sensing approach that an optimal coverage of 12-mer ssLNA sensor probes formed onto gold(111) surface allows recognition of ssDNA targets with twice stronger force sensitivity than 12-mer ssDNA sensor probes. The force distributions are reproducible and the molecule-by-molecule force measurements are largely in agreement with ensemble on-surface melting temperature data. Importantly, the molecularly resolved detection is responsive to the presence of single nucleobase mismatches in target sequences. Since the labelling steps can be eliminated from protocol, and each force-based detection event occurs within milliseconds' time scale, the force-sensing assay is potentially capable of rapid detection. The LNA probe performance is indicative of versatility in terms of substrate choice - be it gold (for basic research and array-based applications) or silicon (for ‘lab-on-a-chip’ type devices). The nucleic acid microarray technologies could therefore be generally benefited by adopting the LNA films, in place of DNA. Since LNA is nuclease-resistant, unlike DNA, and the LNA-based assay is sensitive to single nucleobase mismatches, the possibilities for label-free in vitro rapid diagnostics based on the LNA probes may be explored.
    Keywords: Polymorphism/mutation detection
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
    Published by Oxford University Press
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  • 3
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    Cell biology. Oxygen sensing: it's a gas! (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2004-12-18
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hoshi, Toshinori -- Lahiri, Sukhamay -- New York, N.Y. -- Science. 2004 Dec 17;306(5704):2050-1.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physiology, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. hoshi@hoshi.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15604396" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Carbon Monoxide/*metabolism ; Carotid Body/*cytology/*physiology ; Cell Hypoxia ; Cell Membrane/physiology ; Cells, Cultured ; Heme/metabolism/pharmacology ; Heme Oxygenase (Decyclizing)/genetics/*metabolism ; Hemeproteins/metabolism ; Large-Conductance Calcium-Activated Potassium Channels ; Membrane Potentials ; Mitochondria/metabolism ; NADP/pharmacology ; NADPH Oxidase/metabolism ; Oxidation-Reduction ; Oxygen/*physiology ; Potassium Channels, Calcium-Activated ; Proteomics ; RNA, Small Interfering/pharmacology ; Signal Transduction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Chemical modification of carotid body chemoreception by sulfhydryls (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-05-29
    Description: Sulfhydryl reagents cause striking augmentation of the chemoreceptor responses of the carotid body to hypoxia. This indicates that a cellular plasma membrane protein with a reactive sulfhydryl group is a constituent part of the chemoreceptor architecture and provides a means of identification, localization, and isolation of the protein.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lahiri, S -- HL-19737/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1981 May 29;212(4498):1065-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6262913" target="_blank"〉PubMed〈/a〉
    Keywords: 4-Chloromercuribenzenesulfonate/pharmacology ; Animals ; Carotid Body/drug effects/*physiology ; Cats ; Cell Membrane/physiology ; Chemoreceptor Cells/drug effects/*physiology ; Ethylmaleimide/pharmacology ; Sulfhydryl Compounds/*pharmacology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
    Electronic Resource
    Electronic Resource
    Arsenic toxicity of groundwater in parts of the Bengal basin in India and Bangladesh: the role of Quaternary stratigraphy and Holocene sea-level fluctuation (2000)
    Springer
    Environmental geology 39 (2000), S. 1127-1137 
    Details
    ISSN: 1432-0495
    Keywords: Key words Arsenic in groundwater ; Bangladesh ; Bengal basin ; Deltaic sedimentation ; Holocene sea-level rise ; West Bengal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  Arsenic toxicity in groundwater in the Ganges delta and some low-lying areas in the Bengal basin is confined to middle Holocene sediments. Dissected terraces and highlands of Pleistocene and early Holocene deposits are free of such problems. Arsenic-rich pyrite or other arsenic minerals are rare or absent in the affected sediments. Arsenic appears to occur adsorbed on iron hydroxide-coated sand grains and clay minerals and is transported in soluble form and co-precipitated with, or is scavenged by, Fe(III) and Mn(IV) in the sediments. It became preferentially entrapped in fine-grained and organic-rich sediments during mid-Holocene sea-level rises in deltaic and some low-lying areas of the Bengal basin. It was liberated subsequently under reducing conditions and mediated further by microbial action. Intensive extraction of groundwater for irrigation and application of phosphate fertilizer possibly triggered the recent release of arsenic to groundwater. This practice has induced groundwater flow, mobilizing phosphate derived from fertilizer, as well as from decayed organic matter, which has promoted the growth of sediment biota and aided the further release of arsenic. However, the environment is not sufficiently reducing to mobilize iron and arsenic in groundwater in the Ganges floodplains upstream of Rajmahal. Thus, arsenic toxicity in the groundwater of the Bengal basin is caused by its natural setting, but also appears to be triggered by recent anthropogenic activities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002540000107
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  • 6
    Electronic Resource
    Electronic Resource
    Domestic tax reform and international oligopoly
    Amsterdam : Elsevier
    Journal of Public Economics 51 (1993), S. 55-74 
    Details
    ISSN: 0047-2727
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Economics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0047-2727(93)90004-D
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  • 7
    Electronic Resource
    Electronic Resource
    Short-run energy-economy interactions in Egypt
    Amsterdam : Elsevier
    World Development 12 (1984), S. 799-820 
    Details
    ISSN: 0305-750X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Geography , Political Science , Sociology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0305-750X(84)90075-5
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  • 8
    Electronic Resource
    Electronic Resource
    Elasticity of substitution and the perverse export supply response
    Amsterdam : Elsevier
    Journal of Development Economics 33 (1990), S. 371-375 
    Details
    ISSN: 0304-3878
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Political Science , Economics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0304-3878(90)90029-B
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  • 9
    Electronic Resource
    Electronic Resource
    Imported technologies, urban unemployment and the North-South dialogue
    Amsterdam : Elsevier
    Journal of Development Economics 25 (1987), S. 21-32 
    Details
    ISSN: 0304-3878
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Political Science , Economics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0304-3878(87)90072-1
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  • 10
    Electronic Resource
    Electronic Resource
    Developing an expert system for diagnosis of problem gas chromatographic data
    Amsterdam : Elsevier
    Analytica Chimica Acta 296 (1994), S. 21-31 
    Details
    ISSN: 0003-2670
    Keywords: Expert systems ; Gas chromatography
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0003-2670(94)85146-8
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