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  • 1
    Electronic Resource
    Electronic Resource
    Biosynthesis of folic acid (1966)
    Springer
    Archives of microbiology 53 (1966), S. 33-40 
    Details
    ISSN: 1432-072X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The influence of various vitamins on the biogenesis of folic acid has been studied in microorganisms requiring these as growth factors. In L. arabinosus, the folic acid synthesised was directly proportional to the availability of both riboflavin and pantothenic acid. The influence of cyanocobalamin on folic synthesis varied radically in different organisms. In case of the B12/methionine auxotroph of E. coli there was an inverse relationship of vitamin B12 to folic acid synthesis, while in Euglena the folic acid elaborated was in proportion to cyanocobalamin supplied. Synthesis of both folic acid and vitamin B12 was depressed when thymine supply was adequate in the nutrition of E. coli 15 T -, a thymine auxotroph.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00424737
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  • 2
    Electronic Resource
    Electronic Resource
    Biosynthesis of folic acid (1966)
    Springer
    Archives of microbiology 53 (1966), S. 208-217 
    Details
    ISSN: 1432-072X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Biosynthesis of folic acid activity by Bacillus subtilis cell suspensions was studied with respect to substrates utilized as precursors. Among purine bases, adenine was utilized the best and not guanine although guanosine or guanylic acid were utilized efficiently. Among 3-C precursors, glyceraldehyde gave maximum synthesis of folate activity. The cells appeared to utilize p-aminobenzoate preferentially to p-aminobenzoyl-glutamate. Pteroic acid appears to be an intermediate in the synthesis of folate derivatives in this system. Ascorbic acid stimulates the synthesis to a great extent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00446667
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  • 3
    Electronic Resource
    Electronic Resource
    Biosynthesis of folic acid (1966)
    Springer
    Archives of microbiology 53 (1966), S. 358-370 
    Details
    ISSN: 1432-072X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary It has been attempted to isolate and characterize the folate precursors in the culture filtrates of two folate-requiring organisms, Streptococcus faecalis R and Lactobacillus casei. On the basis of paper chromatography, bioautography, ultra violet absorption spectra, chemical reactions, and differential microbiological responses it has been concluded that L. casei cultures contain a compound similar to pteroic acid which can be utilized by S. faecalis R. The S. faecalis R cultures on the other hand appear to accumulate a pteridine derivative active for Crithidia fasciculata It has been confirmed that this pteridine is not derived from the folic acid usually added to the growth medium.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00409873
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  • 4
    Electronic Resource
    Electronic Resource
    Protective Action of Vitamin B 12 in Experimental Liver Injury (1956)
    [s.l.] : Nature Publishing Group
    Nature 178 (1956), S. 989-989 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Adult male rats (Wistar strain), 100-150 gm. in weight, reared on the laboratory stock diet, were given, intraperitoneally, vitamin B12 (10 µgm. /animal) 3 hr. prior to carbon tetrachloride administration (2 c.c. per kgm. body-weight). It was ascertained from preliminary experiments that ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/178989a0
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  • 5
    Electronic Resource
    Electronic Resource
    Influence of Folic Acid and Vitamin B 12 on the Impairment of Nucleic Acid Synthesis in Lactobacillus casei by Aureomycin (1954)
    [s.l.] : Nature Publishing Group
    Nature 173 (1954), S. 728-729 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The organism employed was Lactobacillus casei (A.T.C.C. 7469). Methods of culturing, harvesting and nucleic acid determinations were as described previously2. A 48-hr, growth of the organism was used. A concentration of aureomycin (crystalline, Lederle) was chosen which produced half maximum growth ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/173728b0
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  • 6
    Electronic Resource
    Electronic Resource
    Pantothenic Acid Deficiency and Ubiquinone Levels in Rat Liver Mitochondria (1959)
    [s.l.] : Nature Publishing Group
    Nature 184 (1959), S. 1867-1868 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Weanling rats (40-50 gm.), Wistar strain, were divided into two groups of six each, one receiving the basal diet consisting of an 18 per cent purified casein ration deficient in pantothenic acid and replete in all other vitamins and the other receiving the same diet supplemented with calcium ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1841867b0
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  • 7
    Electronic Resource
    Electronic Resource
    Folic Acid, Vitamin B 12 and Nucleic Acid Synthesis in Lactobacillus casei (1950)
    [s.l.] : Nature Publishing Group
    Nature 166 (1950), S. 1117-1117 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] With L. casei (ATCC 7469) grown in a medium2 varied with respect to concentrations of folic acid (Lederle) and vitamin B12 (crystalline, Merck), some results of a typical experiment are set forth in the accompanying table. Nucleic acids were extracted by Schneiders procedure7. Ribonucleic acid was ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1661117a0
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  • 8
    Electronic Resource
    Electronic Resource
    Transformation to Prototrophic Condition in Escherichia coli induced by Deoxyribonucleic Acid (1962)
    [s.l.] : Nature Publishing Group
    Nature 193 (1962), S. 296-297 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Escherichia coli (McLeod's) was taken as the donor strain and Escherichia coli, methionino/vitamin B12 auxotroph 113-3 of Davis6 as the recipient strain. DNA was isolated from the donor strain by the method of McCarty and Avery7. The DNA preparation thus obtained, when preserved under 95 per cent ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/193296a0
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  • 9
    Electronic Resource
    Electronic Resource
    Chlorophyll Formation in Euglena gracilis var. bacillaris: Effect of Enzyme Inhibitors (1969)
    Oxford, UK : Blackwell Publishing Ltd
    The @journal of eukaryotic microbiology 16 (1969), S. 0 
    Details
    ISSN: 1550-7408
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: SYNOPSIS. The synthesis of chlorophylls in non-proliferating dark-grown etiolated cells of Euglena gracilis var. bacillaris is markedly inhibited by the enzyme inhibitors dinitrophenol (DNP), p-chloromercuribenzoate (pCMB) and sodium fluoride. The pCMB inhibition of greening is reversed to a great extent by glutathione but not by cysteine. The inhibitory effect of fluoride is reversed by both succinate as well as Mg++ during illumination. Fluoride also inhibits the photosynthetic growth of the euglenas; this inhibition is competitively reversed by succinate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1550-7408.1969.tb02247.x
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  • 10
    Electronic Resource
    Electronic Resource
    On Hemoglobin Inhibition of the Growth of Euglena gracilis (1963)
    Oxford, UK : Blackwell Publishing Ltd
    The @journal of eukaryotic microbiology 10 (1963), S. 0 
    Details
    ISSN: 1550-7408
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: SYNOPSIS. The inhibitory principle in whole blood for strains of Euglena gracilis has been characterized and identified as hemoglobin. Hemoglobins from different sources were tested for their inhibitory activity and gave similar results. The inhibition was reversed by raising the concentration of certain divalent metal ions, calcium in particular in the basal growth medium. The nature of the inhibition was studied. Heme and other porphyrins related to hemoglobin stimulated the growth of Euglena gracilis in light. Implications of these findings are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1550-7408.1963.tb01708.x
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