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  • 1
    Series available for loan
    Series available for loan
    1975-1979 (1980)
    Ottawa : Geological Survey of Canada
    Associated volumes
    Details Availability
    Call number: SR 90.0011(3)
    In: Index to publications
    Type of Medium: Series available for loan
    Pages: 247 S. + 1 Kt.
    ISBN: 066050698X
    Language: English
    Location: Lower compact magazine
    Branch Library: GFZ Library
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  • 2
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    Effect of Surface Hydrophilicity on Charging Mechanism of Colloids in Low-Permittivity Solvents (2007)
    American Chemical Society
    Details
    Publication Date: 2007-01-01
    Print ISSN: 1932-7447
    Electronic ISSN: 1932-7455
    Topics: Chemistry and Pharmacology
    Published by American Chemical Society
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  • 3
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    Pyroxenite Dykes in Orogenic Peridotite from North Qaidam (NE Tibet, China) Track Metasomatism and Segregation in the Mantle Wedge (2014)
    Oxford University Press
    Details
    Publication Date: 2014-12-14
    Description: The early stages of magmatic processes operating at mantle depths beneath continental arcs are poorly known. The chemical compositions of minerals and rocks, mineral Sr–Nd–Hf–O isotopes and zircon U–Pb ages of garnet clinopyroxenite dykes from the Shenglikou peridotite massif (North Qaidam Orogen, NE Tibet, China) were studied to constrain their sources and genesis, and the dynamic processes that controlled pyroxenite formation beneath an early Paleozoic active continental margin. Major-element compositions of bulkrocks suggest that the pyroxenitic protoliths were cumulates segregated from a melt, which was extracted from a peridotite-dominated mantle source. Bulk-rock and mineral trace-element patterns show strong enrichment in fluid-mobile elements (e.g. Cs, Rb, Ba, Th, U, K, Pb and Li) and marked negative anomalies in the high field strength elements relative to rare earth elements, similar to the characteristics of melts derived from a volatile-rich sub-arc mantle. Enriched Sr and Nd initial isotopic compositions at 500 Ma ( 87 Sr/ 86 Sr of 0·70919–0·71774 and Nd of –16·3 to –3·4) are in contrast to the highly radiogenic Hf isotope compositions (similar to those of the depleted-mantle reservoir) and to the uncontaminated upper-mantle 18 O V-SMOW (garnet: 5·6 ± 0·3, 2SD, n = 61; zircon: 5·9 ± 0·3, 2SD, n = 28). These decoupled isotopic signatures suggest that the melt source was located in a convective mantle wedge (controlling the Hf and O isotopes) that had been pervasively metasomatized by fluids from a subducted Proto-Tethys oceanic slab (controlling the Sr–Nd isotopes and highly incompatible elements). Zircons with two groups of U–Pb ages (430 ± 5 Ma and 401 ± 7 Ma) were generated by recrystallization events, corresponding to UHP metamorphism and a major uplift stage during the North Qaidam orogeny, respectively. The combined evidence reveals a picture of continental arc magmatism at mantle depths and subsequent continental collision. The subduction of the Proto-Tethys oceanic slab beneath the southern Qilian margin triggered flux melting of the metasomatized convective mantle wedge and generated hydrous arc magmas. These primitive magmas intruded into the overlying lithospheric mantle and segregated the cumulates parental to the Shenglikou pyroxenites. Subsequent continental subduction incorporated fragments of the mantle-wedge peridotite (containing pyroxenite dykes) at ~430 Ma and carried them to shallow depths during exhumation at ~400 Ma.
    Print ISSN: 0022-3530
    Electronic ISSN: 1460-2415
    Topics: Geosciences
    Published by Oxford University Press
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  • 4
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    Acoustic Signals of Personality (2016)
    Royal Society
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    Publication Date: 2016-07-01
    Description: Social interactions among individuals are often mediated through acoustic signals. If acoustic signals are consistent and related to an individual's personality, these consistent individual differences in signalling may be an important driver in social interactions. However, few studies in non-human mammals have investigated the relationship between acoustic signalling and personality. Here we show that acoustic signalling rate is repeatable and strongly related to personality in a highly social mammal, the domestic pig ( Sus scrofa domestica ). Furthermore, acoustic signalling varied between environments of differing quality, with males from a poor-quality environment having a reduced vocalization rate compared with females and males from an enriched environment. Such differences may be mediated by personality with pigs from a poor-quality environment having more reactive and more extreme personality scores compared with pigs from an enriched environment. Our results add to the evidence that acoustic signalling reflects personality in a non-human mammal. Signals reflecting personalities may have far reaching consequences in shaping the evolution of social behaviours as acoustic communication forms an integral part of animal societies.
    Keywords: behaviour
    Electronic ISSN: 2054-5703
    Topics: Natural Sciences in General
    Published by Royal Society
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  • 5
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    Coexisting Early Cretaceous High-Mg Andesites and Adakitic Rocks in the North China Craton: the Role of Water in Intraplate Magmatism and Cratonic Destruction (2016)
    Oxford University Press
    Details
    Publication Date: 2016-08-30
    Description: High-Mg andesites (HMAs) and adakitic rocks are purported to occur exclusively in subduction zones in the modern Earth. In the North China Craton, early Cretaceous HMAs and adakitic dacites were erupted in a continental setting, apparently unrelated to subduction given their location distal (〉1000 km) to the trench at that time. Here we report petrological, mineralogical and geochemical data for these rocks with the aim of constraining their petrogenesis and elucidating the role of water in intraplate magmatism and cratonic destruction. The HMAs can be subdivided into olivine (Ol-)HMAs and clinopyroxene (Cpx-)HMAs. The former have high MgO (〉9·8 wt %) and Mg# (〉71), with rare high-Fo (up to 91) olivine phenocrysts, corresponding to (near-)primary magmas that equilibrated with mantle peridotite. The latter have moderate MgO (7·8–8·8 wt %) and Mg# (mostly 〈70) and low-Fo (mostly 〈 83) olivine phenocrysts. The Cpx-HMAs are interpreted as magmas differentiated from the Ol-HMAs by olivine-dominated fractionation at lower-crust levels. P–T–X H2O estimations show that the primary HMAs are melts of shallow (1·1–1·2 GPa), hot (~1250°C) and wet (H 2 O 〉 3 wt %) lithospheric mantle. The coexisting adakitic dacites are hydrous (H 2 O ≥ 5 wt %) magmas with high SiO 2 (〉63 wt %), Sr/Y ratios (≥39) and Yb SN (source-normalized), low (Sm/Yb) SN , and negligible Eu anomalies. They also have unradiogenic whole-rock Nd [ Nd ( t ) = –19 to –9] and zircon Hf [ Hf ( t ) = –23 to –21] isotopic compositions consistent with derivation by melting of ancient lower crust at depths 〈 40 km. Melting may have been induced by heating and addition of H 2 O from underplated HMAs. Mixing between Cpx-HMAs and low-Mg adakitic dacites in magma chambers produced high-Mg adakitic rocks. The petrogenetic model presented here explains the occurrence of intraplate HMAs and adakitic magmas elsewhere in the North China Craton. The P–T–X H2O conditions inferred for HMA generation imply that the subcontinental lithospheric mantle beneath the craton was hot and hydrous in the early Cretaceous, which may have triggered the destruction of the cratonic root. The occurrence of young HMAs and adakitic rocks in an intraplate extensional environment also casts doubts on the common use of a similar igneous rock association as an indicator of subduction processes in Archean time.
    Print ISSN: 0022-3530
    Electronic ISSN: 1460-2415
    Topics: Geosciences
    Published by Oxford University Press
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  • 6
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    Bayesian correlated clustering to integrate multiple datasets (2012)
    Oxford University Press
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    Publication Date: 2012-12-08
    Description: Motivation: The integration of multiple datasets remains a key challenge in systems biology and genomic medicine. Modern high-throughput technologies generate a broad array of different data types, providing distinct—but often complementary—information. We present a Bayesian method for the unsupervised integrative modelling of multiple datasets, which we refer to as MDI (Multiple Dataset Integration). MDI can integrate information from a wide range of different datasets and data types simultaneously (including the ability to model time series data explicitly using Gaussian processes). Each dataset is modelled using a Dirichlet-multinomial allocation (DMA) mixture model, with dependencies between these models captured through parameters that describe the agreement among the datasets. Results: Using a set of six artificially constructed time series datasets, we show that MDI is able to integrate a significant number of datasets simultaneously, and that it successfully captures the underlying structural similarity between the datasets. We also analyse a variety of real Saccharomyces cerevisiae datasets. In the two-dataset case, we show that MDI’s performance is comparable with the present state-of-the-art. We then move beyond the capabilities of current approaches and integrate gene expression, chromatin immunoprecipitation–chip and protein–protein interaction data, to identify a set of protein complexes for which genes are co-regulated during the cell cycle. Comparisons to other unsupervised data integration techniques—as well as to non-integrative approaches—demonstrate that MDI is competitive, while also providing information that would be difficult or impossible to extract using other methods. Availability: A Matlab implementation of MDI is available from http://www2.warwick.ac.uk/fac/sci/systemsbiology/research/software/ . Contact: D.L.Wild@warwick.ac.uk Supplementary information: Supplementary data are available at Bioinformatics online.
    Print ISSN: 1367-4803
    Electronic ISSN: 1460-2059
    Topics: Biology , Computer Science , Medicine
    Published by Oxford University Press
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  • 7
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    Storm-event flow pathways in lower coastal plain forested watersheds of the southeastern U.S. (2014)
    Wiley
    Details
    Publication Date: 2014-10-01
    Description: The landscape of the coastal plain of the southeastern United States is rapidly changing due to urbanization and climate-change-related impacts. In addition to the forecasted population increase, this region could experience significant changes in precipitation patterns making watershed management very challenging. In order to establish baseline data, storm-event flow pathways were studied in three lower coastal plain (LCP) forested lowland watersheds of the southeastern United States between 2010-2011. Two of the watersheds had clay loam sub-soils while the third had sandy soils throughout the profile. Stream flow and water samples from water-table wells, piezometers, lysimeters, and rain gauges were analyzed for ion concentrations; ion trends were assessed using principal components analysis; and chemical hydrograph separation was performed for nine storm events using end member mixing analysis. End members consisted of lower concentration rainwater; a near-stream source (riparian or streambed groundwater); and a distant or deep groundwater source. Storm-event stream water on the clayey sites was composed primarily of rainwater (45-67% by volume) and shallow groundwater (21-55%), with small inputs from deep (below the clay-rich soil horizon) groundwater (0.2-21%). At the sandy site, a greater proportion was groundwater (56-61%), with smaller inputs from rainwater (28-33%) and soil water (6-16%). Dry antecedent soil moisture (ASM) conditions and larger storms resulted in greater rainwater contribution at the clayey sites. Shallow groundwater was an important contributor even in dry ASM conditions, perhaps due to the high specific retention of the soils. The results from this study will inform researchers about stormwater routing in forested, shallow water table watersheds and provide land managers with baseline data as they plan stormwater mitigation practices.
    Print ISSN: 0043-1397
    Electronic ISSN: 1944-7973
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Published by Wiley on behalf of American Geophysical Union (AGU).
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  • 8
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    Pathogenic Th17 cells in fatal viral encephalitis [Immunology and Inflammation] (2014)
    National Academy of Sciences
    Details
    Publication Date: 2014-11-12
    Description: Mosquito-borne alphaviruses are important causes of epidemic encephalomyelitis. Neuronal cell death during fatal alphavirus encephalomyelitis is immune-mediated; however, the types of cells involved and their regulation have not been determined. We show that the virus-induced inflammatory response was accompanied by production of the regulatory cytokine IL-10, and in the absence...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
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  • 9
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    Discovery of a small molecule insulin mimetic with antidiabetic activity in mice (1999)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1999-05-13
    Description: Insulin elicits a spectrum of biological responses by binding to its cell surface receptor. In a screen for small molecules that activate the human insulin receptor tyrosine kinase, a nonpeptidyl fungal metabolite (L-783,281) was identified that acted as an insulin mimetic in several biochemical and cellular assays. The compound was selective for insulin receptor versus insulin-like growth factor I (IGFI) receptor and other receptor tyrosine kinases. Oral administration of L-783,281 to two mouse models of diabetes resulted in significant lowering in blood glucose levels. These results demonstrate the feasibility of discovering novel insulin receptor activators that may lead to new therapies for diabetes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zhang, B -- Salituro, G -- Szalkowski, D -- Li, Z -- Zhang, Y -- Royo, I -- Vilella, D -- Diez, M T -- Pelaez, F -- Ruby, C -- Kendall, R L -- Mao, X -- Griffin, P -- Calaycay, J -- Zierath, J R -- Heck, J V -- Smith, R G -- Moller, D E -- New York, N.Y. -- Science. 1999 May 7;284(5416):974-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular Endocrinology, Merck Research Laboratories, R80W250, Post Office Box 2000, Rahway, NJ 07065, USA. bei_zhang@merck.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10320380" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine Triphosphate/metabolism ; Animals ; Ascomycota/*metabolism ; Binding Sites ; Blood Glucose/metabolism ; CHO Cells ; Cricetinae ; Diabetes Mellitus, Type 2/*drug therapy ; Dose-Response Relationship, Drug ; Drug Evaluation, Preclinical ; Enzyme Activation ; Glucose Tolerance Test ; Hyperglycemia/drug therapy ; Hypoglycemic Agents/chemistry/metabolism/*pharmacology/therapeutic use ; Indoles/chemistry/metabolism/*pharmacology/therapeutic use ; Insulin/blood/metabolism/*pharmacology ; Insulin Receptor Substrate Proteins ; Mice ; Mice, Mutant Strains ; Mice, Obese ; Molecular Mimicry ; Phosphoproteins/metabolism ; Phosphorylation ; Protein Conformation/drug effects ; Receptor, Epidermal Growth Factor/metabolism ; Receptor, IGF Type 1/metabolism ; Receptor, Insulin/chemistry/*metabolism ; Signal Transduction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 10
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    A census of dense cores in the Taurus L1495 cloud from the Herschel Gould Belt Survey (2016)
    Oxford University Press
    Details
    Publication Date: 2016-04-17
    Description: We present a catalogue of dense cores in a ~4° x 2° field of the Taurus star-forming region, inclusive of the L1495 cloud, derived from Herschel SPIRE and PACS observations in the 70 μm, 160 μm, 250 μm, 350 μm, and 500 μm continuum bands. Estimates of mean dust temperature and total mass are derived using modified blackbody fits to the spectral energy distributions. We detect 525 starless cores of which ~10–20 per cent are gravitationally bound and therefore presumably prestellar. Our census of unbound objects is ~85 per cent complete for M 〉 0.015 M in low-density regions ( A V 5 mag), while the bound (prestellar) subset is ~85 per cent complete for M 〉 0.1 M overall. The prestellar core mass function (CMF) is consistent with lognormal form, resembling the stellar system initial mass function, as has been reported previously. All of the inferred prestellar cores lie on filamentary structures whose column densities exceed the expected threshold for filamentary collapse, in agreement with previous reports. Unlike the prestellar CMF, the unbound starless CMF is not lognormal, but instead is consistent with a power-law form below 0.3 M and shows no evidence for a low-mass turnover. It resembles previously reported mass distributions for CO clumps at low masses ( M 0.3 M ). The volume density PDF, however, is accurately lognormal except at high densities. It is consistent with the effects of self-gravity on magnetized supersonic turbulence. The only significant deviation from lognormality is a high-density tail which can be attributed unambiguously to prestellar cores.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
    Published by Oxford University Press
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