SFX by Ex Libris Inc.

Title:	Discovery of a small molecule insulin mimetic with antidiabetic activity in mice
Source:	Science [0036-8075] Zhang, B yr:1999

Basic

Sorry, no full text available...

Please use the document delivery service (see below)

Holding information

Holdings in library search engine ALBERT

Document delivery

Request document via Library/Bibliothek

Users interested in this article also expressed an interest in the following:
description	1.	Lin, B. "Identification of novel orally available small molecule insulin mimetics." The Journal of pharmacology and experimental therapeutics 323.2 (2007): 579-585.
description	2.	Bleasdale, J. "Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1b and augment insulin action." Biochemistry 40.19 (2001): 5642-5654.
description	3.	Himms-Hagen, J.. "On raising energy expenditure in ob/ob mice." Science 276.5315 (1997): 1132-1133.
description	4.	Webster, Nicholas J G G. "Signaling effects of demethylasterriquinone B1, a selective insulin receptor modulator." Chembiochem 4.5 (2003): 379-385.
description	5.	Pirola, L. "Modulation of insulin action." Diabetologia 47.2 (2004): 170-84.
description	6.	Liu K, A B B. "Discovery of a potent, highly selective, and orally efficacious small-molecule activator of the insulin receptor." Journal of medicinal chemistry 43.19 (2000): 3487-3494.
description	7.	Verge, D. "Innovative solutions for diabetes therapy." Diabetes Research and Clinical Practice 74.2 (2006).
description	8.	McNaughton, Brian R. "Identification of a Selective Small-Molecule Ligand for HIV-1 Frameshift-Inducing Stem-Loop RNA from an 11,325 Member Resin Bound Dynamic Combinatorial Library." Journal of the American Chemical Society 129.37 (2007): 11306-7.
description	9.	Enoki, T. "Antidiabetic Activities of Chalcones Isolated from a Japanese Herb, Angelica keiskei." Journal of agricultural and food chemistry 55.15 (2007): 6013-6017.
description	10.	Saltiel, A R R. "Insulin signalling and the regulation of glucose and lipid metabolism." Nature 414.6865 (2002): 799-806.
description	11.	Bhaskar, V. "XMetA, an allosteric monoclonal antibody to the insulin receptor, improves glycaemic control in mice with diet-induced obesity." Diabetes, obesity and metabolism 15.3 (2013): 272-275.
description	12.	KORNACKER, M S S. "CITRATE CLEAVAGE ENZYME IN LIVERS OF OBESE AND NONOBESE MICE." Science 144 (1964): 1027-8.
description	13.	Salituro G M, B B M. "Discovery of a small molecule insulin receptor activator." Recent progress in hormone research 56.1 (2001): 107-26.
description	14.	Ghavami, A. "A new class of glycosidase inhibitor: Synthesis of salacinol and its stereoisomers." Journal of organic chemistry 66.7 (2001): 2312-2317.
description	15.	Sarmiento, M. "Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition." Biochemistry 39.28 (2000): 8171-9.
description	16.	Hajduch, E. "Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells." Diabetologia 44.2 (2001): 173-83.
description	17.	Youngren, J. F. "Regulation of insulin receptor function." Cellular and molecular life sciences 64.7 (2007): 873-891.
description	18.	Bhathena, Sam J J. "Relationship between fatty acids and the endocrine and neuroendocrine system." Nutritional neuroscience 9.1-2: 1-10.
description	19.	Mlinar, B. "Molecular mechanisms of insulin resistance and associated diseases." Clinica chimica acta 375.1/2 (2007): 20-35.
description	20.	Taniguchi, Cullen M M. "Critical nodes in signalling pathways: insights into insulin action." Nature reviews. Molecular cell biology 7.2: 85-96.