ISSN:
1420-9071
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Discriminant analysis carried out on a set of environmental and sociocultural variables in the Sardinian population suggests that G-6-PD deficiency and thalassemia move along 2 dimensions partially independent of each other. Partial correlation analysis also suggests that malaria, by itself, may exert opposite effects on thalassemia and G-6-PD selection. The present results support the hypothesis that thalassemia may be the primary genetic factor selected by malaria, whereas G-6-PD selection may be a secondary adaptation phenomenon strongly dependent on other genetic and environmental variables.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01965786
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