Publication Date:
2015-08-15
Description:
Article High insulin/IGF is a biologic link between diabetes and cancer. Here, the authors show a tumour promoting mechanism for stress protein TRB3 which mediates a reciprocal antagonism between autophagic and proteasomal degradation systems and connects insulin/IGF to malignant promotion. Nature Communications doi: 10.1038/ncomms8951 Authors: Fang Hua, Ke Li, Jiao-Jiao Yu, Xiao-Xi Lv, Jun Yan, Xiao-Wei Zhang, Wei Sun, Heng Lin, Shuang Shang, Feng Wang, Bing Cui, Rong Mu, Bo Huang, Jian-Dong Jiang, Zhuo-Wei Hu
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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