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  • 1
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    Robustness of superconductivity to structural disorder in Sr_{0.3} (NH_{2} )_{y} (NH_{3} )_{1−y} Fe_{2} Se_{2} (2015)
    American Physical Society (APS)
    Details
    Publication Date: 2015-10-21
    Description: Author(s): F. R. Foronda, S. Ghannadzadeh, S. J. Sedlmaier, J. D. Wright, K. Burns, S. J. Cassidy, P. A. Goddard, T. Lancaster, S. J. Clarke, and S. J. Blundell The superconducting properties of a recently discovered high- T c superconductor, Sr/ammonia-intercalated FeSe, have been measured using pulsed magnetic fields down to 4.2 K and muon spin spectroscopy down to 1.5 K. This compound exhibits intrinsic disorder resulting from random stacking of the FeSe l… [Phys. Rev. B 92, 134517] Published Tue Oct 20, 2015
    Keywords: Superfluidity and superconductivity
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 2
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    Petrophysical Characterization of Bioturbated Sandstone Reservoir Facies In the Upper Jurassic Ula Formation, Norwegian North Sea, Europe (2015)
    Society for Sedimentary Geology (SEPM)
    Details
    Publication Date: 2015-01-14
    Description: A bstract :  A petrophysical study of bioturbated shoreface sandstone rocks was completed by mapping local variations in air permeability measured in core samples acquired from the Upper Jurassic Ula Formation of the Norwegian Central Graben. Analysis of the shoreface fabrics resulting from bioturbation was studied using arithmetic, harmonic, and geometric numerical modeling and analytical techniques. The arithmetic mean best illustrates samples dominated by high volumes of horizontal or subvertical burrows (50–80%). The distal Skolithos to proximal Cruziana ichnofacies is an example of a rock fabric that can be characterized using the arithmetic mean. The harmonic mean best exemplifies samples dominated by low volumes of vertically oriented burrows (10–50%). The archetypal Skolithos ichnofacies is an example of a rock fabric that can be characterized using the harmonic mean. At extreme volumes of bioturbation (90–100%), isotropic flow units begin developing irrespective of burrow orientation. Numerical models of Ophiomorpha in two different sedimentary bedding features (laminated sandstone and massive sandstone) show that single-phase fluid flow is influenced by parameters such as burrow permeability, burrow connectivity, and bioturbation volume. Spot-permeametry measurements show that the Ophiomorpha burrows have higher permeability values than the host matrix. In the laminated-sandstone models, horizontal shale laminae and low bioturbation intensities promote lamination-parallel fluid flow. At higher volumes of bioturbation, fluid flow becomes increasingly isotropic due to greater amounts of burrow interpenetrations across mud laminae. In the massive-sandstone model, no flow barriers exist. As such, low volumes of bioturbation result in only minor influences on fluid flow. At higher volumes of bioturbation, greater burrow interconnectivity occurs and results in an enhancement of vertical and horizontal burrow permeabilities. Based on the results outlined above, this paper emphasizes the impact bioturbation plays in helping improve reservoir quality in the Ula Formation. Perhaps more importantly, the effectiveness of the numerical models presented to characterize fluid flow in different bioturbated fabrics (e.g., archetypal Skolithos ichnofacies) highlights the fact that the fluid-flow results outlined in this paper can also be applied more broadly to different shoreface successions using ichnofacies knowledge alone.
    Print ISSN: 1527-1404
    Topics: Geosciences
    Published by Society for Sedimentary Geology (SEPM)
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  • 3
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    Neurofibromas in NF1: Schwann cell origin and role of tumor environment (2002)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2002-05-04
    Description: Neurofibromatosis type 1 (NF1) is one of the most prevalent dominantly inherited genetic diseases of the nervous system. NF1 encodes a tumor suppressor whose functional loss results in the development of benign neurofibromas that can progress to malignancy. Neurofibromas are complex tumors composed of axonal processes, Schwann cells, fibroblasts, perineurial cells, and mast cells. Through use of a conditional (cre/lox) allele, we show that loss of NF1 in the Schwann cell lineage is sufficient to generate tumors. In addition, complete NF1-mediated tumorigenicity requires both a loss of NF1 in cells destined to become neoplastic as well as heterozygosity in non-neoplastic cells. The requirement for a permissive haploinsufficient environment to allow tumorigenesis may have therapeutic implications for NF1 and other familial cancers.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024710/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024710/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zhu, Yuan -- Ghosh, Pritam -- Charnay, Patrick -- Burns, Dennis K -- Parada, Luis F -- R01 NS034296/NS/NINDS NIH HHS/ -- R01 NS034296-06/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 2002 May 3;296(5569):920-2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Developmental Biology, Department of Pathology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390-9133, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11988578" target="_blank"〉PubMed〈/a〉
    Keywords: Alleles ; Animals ; Axons/ultrastructure ; Cell Lineage ; Cell Transformation, Neoplastic ; Cells, Cultured ; Cranial Nerves/pathology ; Culture Techniques ; Female ; *Genes, Neurofibromatosis 1 ; Genotype ; Heterozygote ; Hyperplasia ; Loss of Heterozygosity ; Male ; Mast Cells/chemistry/pathology ; Mice ; Mice, Transgenic ; Neurofibroma/genetics/*pathology ; Neurofibromatosis 1/genetics/*pathology ; Peripheral Nerves/pathology ; Schwann Cells/chemistry/*pathology ; Spinal Nerves/pathology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Ecological effects of a major oil spill on panamanian coastal marine communities (1989)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1989-01-06
    Description: In 1986 more than 8 million liters of crude oil spilled into a complex region of mangroves, seagrasses, and coral reefs just east of the Caribbean entrance to the Panama Canal. This was the largest recorded spill into coastal habitats in the tropical Americas. Many population of plants and animals in both oiled and unoiled sites had been studied previously, thereby providing an unprecedented measure of ecological variation before the spill. Documenation of the spread of oil and its biological begun immediately. Intertidal mangroves, algae, and associated invertebrates were covered by oil and died soon after. More surprisingly, there was also extensive mortality of shallow subtidal reef corals and infauna of seagrass beds. After 1.5 years only some organisms in areas exposed to the open sea have recovered.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jackson, J B -- Cubit, J D -- Keller, B D -- Batista, V -- Burns, K -- Caffey, H M -- Caldwell, R L -- Garrity, S D -- Getter, C D -- Gonzalez, C -- Guzman, H M -- Kaufmann, K W -- Knap, A H -- Levings, S C -- Marshall, M J -- Steger, R -- Thompson, R C -- Weil, E -- New York, N.Y. -- Science. 1989 Jan 6;243(4887):37-44.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17780421" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction (2019)
    Springer Nature
    Details
    Publication Date: 2019
    Print ISSN: 1097-6256
    Electronic ISSN: 1546-1726
    Topics: Biology , Medicine
    Published by Springer Nature
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  • 6
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    A restricted cell population propagates glioblastoma growth after chemotherapy (2012)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2012-08-03
    Description: Glioblastoma multiforme is the most common primary malignant brain tumour, with a median survival of about one year. This poor prognosis is due to therapeutic resistance and tumour recurrence after surgical removal. Precisely how recurrence occurs is unknown. Using a genetically engineered mouse model of glioma, here we identify a subset of endogenous tumour cells that are the source of new tumour cells after the drug temozolomide (TMZ) is administered to transiently arrest tumour growth. A nestin-DeltaTK-IRES-GFP (Nes-DeltaTK-GFP) transgene that labels quiescent subventricular zone adult neural stem cells also labels a subset of endogenous glioma tumour cells. On arrest of tumour cell proliferation with TMZ, pulse-chase experiments demonstrate a tumour re-growth cell hierarchy originating with the Nes-DeltaTK-GFP transgene subpopulation. Ablation of the GFP+ cells with chronic ganciclovir administration significantly arrested tumour growth, and combined TMZ and ganciclovir treatment impeded tumour development. Thus, a relatively quiescent subset of endogenous glioma cells, with properties similar to those proposed for cancer stem cells, is responsible for sustaining long-term tumour growth through the production of transient populations of highly proliferative cells.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427400/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427400/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chen, Jian -- Li, Yanjiao -- Yu, Tzong-Shiue -- McKay, Renee M -- Burns, Dennis K -- Kernie, Steven G -- Parada, Luis F -- R01 CA131313/CA/NCI NIH HHS/ -- R01 NS048192-01/NS/NINDS NIH HHS/ -- England -- Nature. 2012 Aug 23;488(7412):522-6. doi: 10.1038/nature11287.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/22854781" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antineoplastic Agents, Alkylating/pharmacology/therapeutic use ; Brain Neoplasms/*drug therapy/*pathology ; Cell Proliferation/drug effects ; Cell Tracking ; Dacarbazine/*analogs & derivatives/pharmacology/therapeutic use ; Disease Models, Animal ; Disease Progression ; Female ; Ganciclovir/pharmacology ; Glioblastoma/*drug therapy/*pathology ; Green Fluorescent Proteins/genetics/metabolism ; Male ; Mice ; Mice, Transgenic ; Neoplastic Stem Cells/*drug effects/*pathology ; Neural Stem Cells/drug effects/pathology ; Transgenes/genetics
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 7
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    Bone cells: a serum-free medium supports proliferation in primary culture (1978)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1978-02-03
    Description: Bone-cells isolated from embryonic rat calvaria increase in number two-to threefold when cultured at high, but not at low, population densities in a serum-free medium that contains albumin. Cultured cells respond to parathyroid hormone and exhibit a marked rise in alkaline phosphatase activity during proliferation, which suggests the progressive differentiation or preferential growth of osteoblast-like cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Burns, J K -- Peck, W A -- New York, N.Y. -- Science. 1978 Feb 3;199(4328):542-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/564080" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bone Development ; Bone and Bones/*cytology ; Cell Differentiation ; Cell Division ; *Cells, Cultured ; Culture Media ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    A Revised and Expanded Structure Hierarchy of Natural and Synthetic Hexavalent Uranium Compounds (2017)
    Mineralogical Association of Canada
    Details
    Publication Date: 2017-01-05
    Description: Over the past four decades, the number of inorganic oxide and oxy-salt phases containing stoichiometric quantities of hexavalent uranium has increased exponentially from a few dozen to well over 700, and these structures have become well-known for their remarkable compositional diversity and topological variability. Considering the entirety of these compounds ( i . e ., crystal structures, conditions of synthesis, and geological occurrences) offers significant insight into the behavior of uranium in the solid state and in the nascent (typically aqueous) fluids. The structure hierarchy approach adopted here aims specifically to facilitate the recognition of useful patterns in the crystal-chemical behavior of hexavalent uranium (U 6+ ). This work represents the third attempt at a structure hierarchy of U 6+ compounds, with the first two being those of Burns et al . (1996) and Burns (2005) , which considered 180 and 368 structures, respectively. The current work is expanded to include the structures of 727 known, well-refined synthetic compounds (610) and minerals (117) that contain stoichiometric quantities of U 6+ . As in the previous works, structures are systematically ordered on the basis of topological similarity, as defined predominantly by the polymerization of high-valence cations. The updated breakdown is as follows: (1) isolated polyhedra (24 compounds/0 minerals); (2) finite clusters (70 compounds/10 minerals); (3) infinite chains (94 compounds/15 minerals); (4) infinite sheets (353 compounds/79 minerals); and (5) frameworks (186 compounds/13 minerals). Within each of these major categories, structures are sub-divided on the basis of increasing connectivity of uranium (nearly always uranyl) polyhedra. In addition to elucidating common trends in U 6+ crystal chemistry, this structure hierarchy will serve as a comprehensive introduction for those not yet fluent in the domain of uranium mineralogy and inorganic, synthetic uranium chemistry.
    Print ISSN: 0008-4476
    Topics: Geosciences
    Published by Mineralogical Association of Canada
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  • 9
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    Petrology and Diagenetic Effects of Graywacke Sandstones--Eocene Umpqua Formation, Southwest Oregon: ABSTRACT (1977)
    American Association of Petroleum Geologists
    Details
    Publication Date: 1977-01-01
    Print ISSN: 0149-1423
    Electronic ISSN: 1943-2674
    Topics: Geosciences
    Published by American Association of Petroleum Geologists
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  • 10
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    The Gravity Probe B test of general relativity (2015)
    Institute of Physics
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    Publication Date: 2015-11-17
    Print ISSN: 0264-9381
    Electronic ISSN: 1361-6382
    Topics: Physics
    Published by Institute of Physics
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