Publication Date:
2005-08-20
Description:
The SAR11 clade consists of very small, heterotrophic marine alpha-proteobacteria that are found throughout the oceans, where they account for about 25% of all microbial cells. Pelagibacter ubique, the first cultured member of this clade, has the smallest genome and encodes the smallest number of predicted open reading frames known for a free-living microorganism. In contrast to parasitic bacteria and archaea with small genomes, P. ubique has complete biosynthetic pathways for all 20 amino acids and all but a few cofactors. P. ubique has no pseudogenes, introns, transposons, extrachromosomal elements, or inteins; few paralogs; and the shortest intergenic spacers yet observed for any cell.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Giovannoni, Stephen J -- Tripp, H James -- Givan, Scott -- Podar, Mircea -- Vergin, Kevin L -- Baptista, Damon -- Bibbs, Lisa -- Eads, Jonathan -- Richardson, Toby H -- Noordewier, Michiel -- Rappe, Michael S -- Short, Jay M -- Carrington, James C -- Mathur, Eric J -- New York, N.Y. -- Science. 2005 Aug 19;309(5738):1242-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Microbiology, Oregon State University, Corvallis, OR 97331, USA. steve.giovannoni@oregonstate.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16109880" target="_blank"〉PubMed〈/a〉
Keywords:
Alphaproteobacteria/classification/*genetics/isolation & purification/physiology
;
Bacterial Proteins/genetics/metabolism
;
Base Composition
;
Biological Evolution
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Carbon/metabolism
;
Computational Biology
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DNA, Bacterial/chemistry/genetics
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DNA, Intergenic
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Gene Expression Regulation, Bacterial
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Genes, Bacterial
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*Genome, Bacterial
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Membrane Transport Proteins/genetics/metabolism
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Molecular Sequence Data
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Oceans and Seas
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Phosphates/metabolism
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Phylogeny
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Seawater/*microbiology
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Selection, Genetic
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Sigma Factor/genetics
;
Thymidylate Synthase/genetics
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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