Publication Date:
2013-04-27
Description:
Leathers and Olson (Reports, 5 October 2012, p. 132) draw the strong conclusion that neurons in the monkey lateral intraparietal (LIP) cortical area encode only cue salience, and not action value, during value-based decision-making. Although their findings regarding cue salience are interesting, their broader conclusions are problematic because (i) their primary conclusion is based on responses observed during a brief interval at the beginning of behavioral trials but is extended to all subsequent temporal epochs and (ii) the authors failed to replicate basic hallmarks of LIP physiology observed in those subsequent temporal epochs by many laboratories.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045496/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉 〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045496/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Newsome, William T -- Glimcher, Paul W -- Gottlieb, Jacqueline -- Lee, Daeyeol -- Platt, Michael L -- R01 MH096875/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 2013 Apr 26;340(6131):430. doi: 10.1126/science.1233214.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Neurobiology and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23620037" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
*Cues
;
Decision Making/*physiology
;
Male
;
Motivation/*physiology
;
Neurons/*physiology
;
Saccades/*physiology
;
*Social Values
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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