Publication Date:
2017-11-22
Description:
As an extension of the boron enolate-based aldol reactions, the oxazolidinone-installed bisimide 1a from 3-(trifluoromethyl)glutaric acid was employed for Mannich reactions with tosylated imines 2 as electrophiles to successfully obtain the corresponding adducts in a stereoselective manner. Beilstein J. Org. Chem. 2017, 13, 2473–2477. doi:10.3762/bjoc.13.244
Keywords:
chiral oxazolidinonesdiastereoselectivityMannich reactionspseudo-C2 symmetrytrifluoromethyl
Electronic ISSN:
1860-5397
Topics:
Chemistry and Pharmacology
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