ISSN:
0009-2940
Keywords:
Annelated pyridines, preparation from Mannich bases
;
5,6-Dihydro-1,10-phenanthrolines, substituted
;
4,5-Diazafluorenes, substituted
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
β-Amino Ketones as Key Intermediates in the Synthesis of Pyridines: A Novel and Efficient Route to Annelated Bi- and TerpyridinesThe hydrochlorides of β-amino ketones 1a - e (Mannich bases) are easily obtained starting compounds for a novel synthesis of pyridines. Condensation with the heteroaromatic ketones 8, 9, and 10 yields 5,6-dihydro-1,10-phenanthrolines 3a - d, 13 and 4,5-diazafluorenes 4a - d, which have not yet been described in literature. Symmetrical terpyridines 3e, 4e are formed in a one-step reaction of 8, 9 with dimethylmethylenammonium chloride in the presence of an ammonia source.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19911240324
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