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    Publication Date: 2017-10-28
    Description: The antimalarial activity of the pantothenamide α-PanAm is via inhibition of pantothenate phosphorylation Scientific Reports, Published online: 27 October 2017; doi:10.1038/s41598-017-14074-9
    Electronic ISSN: 2045-2322
    Topics: Natural Sciences in General
    Published by Springer Nature
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  • 3
    Publication Date: 2004-12-03
    Description: NASA Glenn Research Center (GRC) has developed a Fault-Tolerant Magnetic Bearing Suspension rig to enhance the bearing system safety. It successfully demonstrated that using only two active poles out of eight redundant poles from each radial bearing (that is, simply 12 out of 16 poles dead) levitated the rotor and spun it without losing stability and desired position up to the maximum allowable speed of 20,000 rpm. In this paper, it is demonstrated that as far as the summation of force vectors of the attracting poles and rotor weight is zero, a fault-tolerant magnetic bearing system maintained the rotor at the desired position without losing stability even at the maximum rotor speed. A proportional-integral-derivative (PID) controller generated autonomous corrective actions with no operator's input for the fault situations without losing load capacity in terms of rotor position. This paper also deals with a centralized modal controller to better control the dynamic behavior over system modes.
    Keywords: Mechanical Engineering
    Type: 35th Aerospace Mechanisms Symposium; 127-132; NASA/CP-2001-209626
    Format: text
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  • 4
    Publication Date: 2013-08-31
    Description: This paper presents the development of a general-purpose fuzzy logic (FL) control methodology for isolating the external vibratory disturbances of space-based devices. According to the desired performance specifications, a full investigation regarding the development of an FL controller was done using different scenarios, such as variances of passive reaction-compensating components and external disturbance load. It was shown that the proposed FL controller is robust in that the FL-controlled system closely follows the prespecified ideal reference model. The comparative study also reveals that the FL-controlled system achieves significant improvement in reducing vibrations over passive systems.
    Keywords: CYBERNETICS
    Type: The 28th Aerospace Mechanisms Symposium; p 159-165; NASA-CP-3260
    Format: application/pdf
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  • 5
    Publication Date: 2013-08-31
    Description: Increasing research is being done into industrial uses for the microgravity environment aboard orbiting space vehicles. However, there is some concern over the effects of reaction forces produced by moving objects, especially motors, robotic actuators, and astronauts. Reaction forces produced by the movement of these objects may manifest themselves as undesirable accelerations in the space vehicle making the vehicle unusable for microgravity applications. It is desirable to provide compensation for such forces using active means. This paper presents the design and experimental evaluation of the NASA three degree of freedom reaction compensation platform, a system designed to be a testbed for the feasibility of active attenuation of reaction forces caused by moving objects in a microgravity environment. Unique 'linear motors,' which convert electrical current directly into rectilinear force, are used in the platform design. The linear motors induce accelerations of the displacer inertias. These accelerations create reaction forces that may be controlled to counteract disturbance forces introduced to the platform. The stated project goal is to reduce reaction forces by 90 percent, or -20 dB. Description of the system hardware, characterization of the actuators and the composite system, and design of the software safety system and control software are included.
    Keywords: SPACECRAFT DESIGN, TESTING AND PERFORMANCE
    Type: The 28th Aerospace Mechanisms Symposium; p 147-152; NASA-CP-3260
    Format: application/pdf
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  • 6
    Publication Date: 2018-06-05
    Description: Linear-Quadratic-Gaussian (LQG) control is a modern state-space technique for designing optimal dynamic regulators. It enables us to trade off regulation performance and control effort, and to take into account process and measurement noise. The Structural Mechanics and Dynamics Branch at the NASA Glenn Research Center has developed an LQG control for a fault-tolerant magnetic bearing suspension rig to optimize system performance and to reduce the sensor and processing noise. The LQG regulator consists of an optimal state-feedback gain and a Kalman state estimator. The first design step is to seek a state-feedback law that minimizes the cost function of regulation performance, which is measured by a quadratic performance criterion with user-specified weighting matrices, and to define the tradeoff between regulation performance and control effort. The next design step is to derive a state estimator using a Kalman filter because the optimal state feedback cannot be implemented without full state measurement. Since the Kalman filter is an optimal estimator when dealing with Gaussian white noise, it minimizes the asymptotic covariance of the estimation error.
    Keywords: Numerical Analysis
    Type: Research and Technology 2001; NASA/TM-2002-211333
    Format: application/pdf
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  • 7
    Publication Date: 2018-06-05
    Description: The Structural Mechanics and Dynamics Branch has successfully demonstrated a fail-safe controller for the Fault-Tolerant Magnetic Bearing rig at the NASA Glenn Research Center. The rotor is supported by two 8-pole redundant radial bearings, and coil failing situations are simulated by manually shutting down their control current commands from the controller cockpit. The effectiveness of the controller was demonstrated when only two active coils from each radial bearing could be used (that is, 14 coils failed). These remaining two coils still levitated the rotor and spun it without losing stability or desired position up to the maximum allowable speed of 20,000 rpm.
    Keywords: Mechanical Engineering
    Type: Research and Technology 2000; NASA/TM-2001-210605
    Format: text
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  • 8
    Publication Date: 2018-06-02
    Description: Because of its high efficiency, fuel cell technology may be used to launch a new generation of more-electric aeropropulsion and power systems for future aircraft. Electric-motor-driven airplanes using fuel-cell powerplants would be beneficial to the environment because of fuel savings, low noise, and zero carbon-dioxide emissions. In spite of the fuel cell s efficiency benefit, to produce the same shaft drive power, a fuel cell- powered electric-drive system must be definitely heavier than a turbine-drive system. However, the fuel-cell system s overall efficiency from fuel-to-shaft power is higher than for a turbine-drive system. This means that the fuel consumption rate could be lower than for a conventional system. For heavier, fuel-laden planes for longer flights, we might achieve substantial fuel savings. In the airplane industry, in fact, an efficiency gain of even a few percentage points can make a major economic difference in operating costs.
    Keywords: Aircraft Propulsion and Power
    Type: Research and Technology 2004; NASA/TM-2005-213419
    Format: application/pdf
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  • 9
    Publication Date: 2018-06-02
    Description: The NASA Glenn Research Center's Structural Mechanics and Dynamics Branch is developing a compact, nonpolluting, bearingless electric machine with electric power supplied by fuel cells for future "more-electric" aircraft with specific power in the projected range of 50 hp/lb, whereas conventional electric machines generate usually 0.2 hp/lb. The use of such electric drives for propulsive fans or propellers depends on the successful development of ultra-high-power-density machines. One possible candidate for such ultra-high-power-density machines, a round-rotor synchronous machine with an engineering current density as high as 20,000 A/sq cm, was selected to investigate how much torque and power can be produced.
    Keywords: Aircraft Design, Testing and Performance
    Type: Research and Technology 2003; NASA/TM-2004-212729
    Format: application/pdf
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  • 10
    Publication Date: 2018-06-02
    Description: The Structural Mechanics and Dynamics Branch at the NASA Glenn Research Center has developed a three-axis high-temperature magnetic bearing suspension rig to enhance the safety of the bearing system up to 1000 F. This test rig can accommodate thrust and radial bearings up to a 22.84 cm (9 in.) diameter with a maximum axial loading of 22.25 kN (5000 lb) and a maximum radial loading up to 4.45 kN (1000 lb). The test facility was set up to test magnetic bearings under high-temperature (1100 F) and high-speed (20,000 rpm) conditions. The magnetic bearing is located at the center of gravity of the rotor between two high-temperature grease-packed mechanical ball bearings. The drive-end duplex angular contact ball bearing, which is in full contact, acts as a moment release and provides axial stability. The outboard end ball bearing has a 0.015-in. radial clearance between the rotor to act as a backup bearing and to compensate for axial thermal expansion. There is a 0.020-in. radial air gap between the stator pole and the rotor. The stator was wrapped with three 1-kW band heaters to create a localized hot section; the mechanical ball bearings were outside this section. Eight threaded rods supported the stator. These incorporated a plunger and Bellville washers to compensate for radial thermal expansion and provide rotor-to-stator alignment. The stator was instrumented with thermocouples and a current sensor for each coil. Eight air-cooled position sensors were mounted outside the hot section to monitor the rotor. Another sensor monitored this rotation of the outboard backup bearing. Ground fault circuit interrupts were incorporated into all power amplifier loops for personnel safety. All instrumentation was monitored and recorded on a LabView-based data acquisition system. Currently, this 12-pole heteropolar magnetic bearing has 13 thermal cycles and over 26 hr of operation at 1000 F.
    Keywords: Mechanical Engineering
    Type: Research and Technology 2001; NASA/TM-2002-211333
    Format: application/pdf
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