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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Biological cybernetics 3 (1966), S. 175-185 
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Summary In isolated receptors the impulse frequency following “step” stretches had a highly significant correlation with both muscle length and tension; any deviations from linearity were in opposite directions, impulse frequency rising more quickly than linearly with length and more slowly than linearly with tension. The impulse frequency decayed according to a power function of time from application of a step increase in length. A transfer function was derived and used to predict responses to sinusoidal and constant velocity stretches. The experimental data generally agreed with predictions. The deviations that were found could be accounted for by considering quantitatively any non-linearity between frequency and length, the adaptation of the impulse frequency to constant currents, the all-or-none nature of the action potential, and the viscous forces present during dynamic stretch. The approximately linear relationship between impulse frequency and muscle length and muscle tension is discussed. Muscle tension appears to be the more direct causal agent of impulse generation. Possible physical bases for the transfer function are also considered.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Neuroscience 4 (1981), S. 17-42 
    ISSN: 0147-006X
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Plant pathology 33 (1984), S. 0 
    ISSN: 1365-3059
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Mycelial isolates (115) of Pseudocercosporella herpotrichoides were obtained from five field sites in England. Carbendazim-resistant isolates were detected by their mycelial growth on agar containing 1 μg/ml carbendazim. Resistant isolates were found at two of the five sites examined and one of these had never been treated with benzimidazole fungicides. Amongst the carbendazim- resistant isolates there was a predominance of isolates with pale mycelium, an irregular colony margin and a relatively slow growth rate; however, this association was not absolute. Large differences in the effects of carbendazim on mycelial growth of sensitive and resistant isolates were demonstrated; growth of sensitive isolates was completely inhibited at 0.5 μg /ml carbendazim whilst five of the six resistant isolates examined grew on agar containing 1000 μg/ml fungicide. The carbendazim-resistant isolates were cross-resistant to benomyl, thiophanate-methyl and to a Icsser degree thiabendazole, but not to prochloraz. Conidia of carbendazim-resistant isolates were as resistant. Carbendazim-resistant isolates were just as pathogenic to wheat as sensitive isolates. The implications of these results and other reports of benzimidazole resistance in P. herpotrichoides are discussed in relation to disease control.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 304 (1983), S. 741-742 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Experiments were carried out on the sheet-like gluteus muscle of neonatal rats aged 0-1 days and 13-17 days. The muscle (Fig. 1) varies between 12 and 25 fibres thick and is innervated by about 20 motor axons. It arises medially from the iliac crest and inserts into the femur and fascia of the ...
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 24 (1968), S. 1210-1211 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé On a enregistré des décharges de 17 fibres fusimotrices dont on suppose l'existence dans les filaments de racines ventrales des chats décérébrés. 8 fibres ont été inhibées par stimulation répétée de la portion centrale isolée du reste de la racine ventrale. Ces résultats montrent qu'il existe une inhibition antidromique dans les neurones fusimoteurs.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 282 (1979), S. 724-726 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The soleus muscles in young adult mice anaesthetised with chloral hydrate were partially denervated by cutting one or both L4 rarni, or were completely denervated by crushing the soleus nerve close to the muscle. Teflon-coated multi-stranded stainless steel wires were implanted on both sides of the ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 265 (1977), S. 459-460 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] TTX was used because it is a specific blocker of Na+ conductance in nerve5 and does not interfere with axo-plasmic transport6,7. This is important becauseDiamond et al.8,9 believe that interference with axoplasmic flow can lead to sprouting. Adult mice, male and female (20-30 g), were anaesthetised ...
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  • 8
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 275 (1978), S. 652-654 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We produced muscles with afferent nerve fibre degeneration but with normal efferent innervation by cutting the dorsal roots supplying the muscles, peripheral to the dorsal root ganglia. We used the soleus and peroneus tertius muscles of mice weighing 30 g or more. Under chloral hydrate anaesthesia ...
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Empirical economics 14 (1989), S. 273-289 
    ISSN: 1435-8921
    Source: Springer Online Journal Archives 1860-2000
    Topics: Economics
    Notes: Abstract This paper makes use of the fact that the stock of medical manpower in Canada is institutionally and exogenously determined in order to develop a model predicting physician average net income. An econometric evaluation of this model on a sample involving Canada's ten provinces during 1968–1982 suggests that a one per cent increase in physician fees increases physician average net income by 0.70 per cent, and a one per cent increase in the physician to population ratio reduces average net income by 0.62 per cent. In both cases, the elasticities are less than unity because the supply function for an individual physician is backward bending — on average, a Canadian physician reduces his hours worked by an amount between 0.17 and 0.50 per cent (95 per cent confidence interval) if his real wage rate is increased by one per cent.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 16 (1978), S. 408-418 
    ISSN: 1741-0444
    Keywords: Activity ; Metrifonate ; Oxamniquine ; Schistosome ; Ultrasonics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Description / Table of Contents: Sommaire Il décrit une méthode de mise au point et d'application in vitro, de l'effet de médicaments antischistosome sur l'activité des schistosomes. Le système décrit enregistre l'activité de troubles causés par les mouvements des vers, dans un champ ultrasonore de 10 MHz. Les enregistrements de l'activité, allant jusqu'à 10 canaus, sont relevés par ordinateur, et les changements d'activité sont évalués au moyen de statistique. On démontre et étudie les changement d'activité, dus aux réactions des Métrifonate et Oxamniquine.
    Abstract: Zusammenfassung Eine Methode zur Feststellung der Wirkung schistosomalhemmender Medikamente auf die Tätigkeit der Schistosomen in vitro wurde erarbeitet und ausgewertet. Die Methode erläutert Tätigkeitsaufzeichnungen, der durch die Wurmbewegungen erzeugten Unregelmäßigkeiten in einem 10 MHz Ultraschallfeld. Tätigkeitsaufzeichnungen von bis zu 10 Kanälen werden von einem Computer aufgezeichnet und die Tätigkeitsveränderungen werden zufriedenstellend ausgewertet. Es werden die Tätigkeitsveränderungen in bezug auf Metrifonate und Oxamniquine dargestellt und diskutiert.
    Notes: Abstract A method of assessing the effect of antischistosomal drugs on the activity of schistosomes,in vitro has been devised and exploited. The system described records activity from the disturbances caused by the worm movements in a 10 MHz ultrasonic field. Activity recordings from up to 10 channels are plotted by computer, and changes in activity evaluated statistically. The activity changes in response to Metrifonate and to Oxamniquine are demonstrated and discussed
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