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  • 1
    Publication Date: 2001-10-06
    Description: We synthesized multimetal microrods intrinsically encoded with submicrometer stripes. Complex striping patterns are readily prepared by sequential electrochemical deposition of metal ions into templates with uniformly sized pores. The differential reflectivity of adjacent stripes enables identification of the striping patterns by conventional light microscopy. This readout mechanism does not interfere with the use of fluorescence for detection of analytes bound to particles by affinity capture, as demonstrated by DNA and protein bioassays.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nicewarner-Pena, S R -- Freeman, R G -- Reiss, B D -- He, L -- Pena, D J -- Walton, I D -- Cromer, R -- Keating, C D -- Natan, M J -- HG02228/HG/NHGRI NIH HHS/ -- New York, N.Y. -- Science. 2001 Oct 5;294(5540):137-41.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Chemistry, Pennsylvania State University, 152 Davey Laboratory, University Park, PA 16802, USA., SurroMed Inc., 2375 Garcia Avenue, Mountain View, CA 94043, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11588257" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Biochemistry/*methods ; Chemistry Techniques, Analytical/*methods ; Electrochemistry ; Fluorescence ; Fluorescent Antibody Technique ; Humans ; Immunoassay/*methods ; Immunoglobulin G/analysis ; *Metals ; Microscopy ; Miniaturization ; Nucleic Acid Hybridization/*methods ; Oligonucleotide Probes ; Optics and Photonics ; Rabbits ; Templates, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2004-01-13
    Description: We report a virus-based scaffold for the synthesis of single-crystal ZnS, CdS, and freestanding chemically ordered CoPt and FePt nanowires, with the means of modifying substrate specificity through standard biological methods. Peptides (selected through an evolutionary screening process) that exhibit control of composition, size, and phase during nanoparticle nucleation have been expressed on the highly ordered filamentous capsid of the M13 bacteriophage. The incorporation of specific, nucleating peptides into the generic scaffold of the M13 coat structure provides a viable template for the directed synthesis of semiconducting and magnetic materials. Removal of the viral template by means of annealing promoted oriented aggregation-based crystal growth, forming individual crystalline nanowires. The unique ability to interchange substrate-specific peptides into the linear self-assembled filamentous construct of the M13 virus introduces a material tunability that has not been seen in previous synthetic routes. Therefore, this system provides a genetic toolkit for growing and organizing nanowires from semiconducting and magnetic materials.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mao, Chuanbin -- Solis, Daniel J -- Reiss, Brian D -- Kottmann, Stephen T -- Sweeney, Rozamond Y -- Hayhurst, Andrew -- Georgiou, George -- Iverson, Brent -- Belcher, Angela M -- New York, N.Y. -- Science. 2004 Jan 9;303(5655):213-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Departments of Chemistry and Biochemistry, University of Texas (UT) at Austin, Austin, TX 78712, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/14716009" target="_blank"〉PubMed〈/a〉
    Keywords: Alloys/chemistry ; *Bacteriophage M13/genetics/metabolism ; Cadmium Compounds/chemistry ; Capsid/metabolism ; Crystallization ; *Magnetics ; Monte Carlo Method ; Nanotechnology/*methods ; Peptide Library ; *Peptides/chemistry/metabolism ; Platinum Compounds/chemistry ; Recombinant Fusion Proteins/chemistry/metabolism ; *Semiconductors ; Sulfides/chemistry ; Thermodynamics ; Zinc Compounds
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2006-02-20
    Print ISSN: 0003-6951
    Electronic ISSN: 1077-3118
    Topics: Physics
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