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  • 1
    Monograph available for loan
    Monograph available for loan
    Die klimatischen Verhältnisse der Stadt Meissen (1890)
    Meissen : Louis Mosche
    Details Availability
    Call number: MOP 43917 / Mitte
    Type of Medium: Monograph available for loan
    Pages: II, 124 Seiten , mit zwei lithographischen Tafeln
    Language: German
    Location: MOP - must be ordered
    Branch Library: GFZ Library
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  • 2
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    Stabilization of Water Droplets in an Oily Matrix Exclusively by Gel Formation (2012)
    Wiley
    Details
    Publication Date: 2012-04-15
    Description: As droplets in emulsions are thermodynamically unstable, surfactants are required for their stabilization. However, these additives often are unwanted due to legal restrictions and possible health threats. Gelling of the aqueous phase poses one promising alternative. Only droplet-forming processes like microfluidic devices are known to successfully work so far for stabilization by gelling. As these processes are hard to scale-up and tend to foul, a technical alternative based on commonly used high-pressure homogenization is investigated. A nozzle was adapted by adding a micromixer directly behind the orifice outlet. This allowed gelling and stabilizing the droplets by feeding a cold oil stream immediately after droplet breakup. Up to 40 wt-% droplets with Sauter mean diameters down to the micrometer range could be successfully stabilized. An alternative way in stabilizing emulsion droplets is investigated. The idea of exclusive stabilization by gelling of the droplets was transferred to a high-pressure homogenizer. Stabilization is realized by means of forming a pectin gel matrix in the water droplets directly after droplet disruption. Possibilities for processing of surfactant-free emulsions and limitations of this process are discussed.
    Print ISSN: 0930-7516
    Electronic ISSN: 1521-4125
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Published by Wiley
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  • 3
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    Stabilization of Water Droplets in an Oily Matrix Exclusively by Gel Formation (2012)
    Wiley
    Details
    Publication Date: 2012-03-13
    Description: As droplets in emulsions are thermodynamically unstable, surfactants are required for their stabilization. However, these additives often are unwanted due to legal restrictions and possible health threats. Gelling of the aqueous phase poses one promising alternative. Only droplet-forming processes like microfluidic devices are known to successfully work so far for stabilization by gelling. As these processes are hard to scale-up and tend to foul, a technical alternative based on commonly used high-pressure homogenization is investigated. A nozzle was adapted by adding a micromixer directly behind the orifice outlet. This allowed gelling and stabilizing the droplets by feeding a cold oil stream immediately after droplet breakup. Up to 40 wt-% droplets with Sauter mean diameters down to the micrometer range could be successfully stabilized. An alternative way in stabilizing emulsion droplets is investigated. The idea of exclusive stabilization by gelling of the droplets was transferred to a high-pressure homogenizer. Stabilization is realized by means of forming a pectin gel matrix in the water droplets directly after droplet disruption. Possibilities for processing of surfactant-free emulsions and limitations of this process are discussed.
    Print ISSN: 0930-7516
    Electronic ISSN: 1521-4125
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Published by Wiley
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  • 4
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    Origin and evolution of two-component debris discs and an application to the q1 Eridani system (2016)
    Oxford University Press
    Details
    Publication Date: 2016-07-13
    Description: Many debris discs reveal a two-component structure, with an outer Kuiper-belt analogue and a warm inner component whose origin is still a matter of debate. One possibility is that warm emission stems from an ‘asteroid belt’ closer in to the star. We consider a scenario in which a set of giant planets is formed in an initially extended planetesimal disc. These planets carve a broad gap around their orbits, splitting up the disc into the outer and the inner belts. After the gas dispersal, both belts undergo collisional evolution in a steady-state regime. This scenario is explored with detailed collisional simulations involving realistic physics to describe a long-term collisional depletion of the two-component disc. We find that the inner disc may be able to retain larger amounts of material at older ages than thought before on the basis of simplified analytic models. We show that the proposed scenario is consistent with a suite of thermal emission and scattered light observational data for a bright two-temperature debris disc around a nearby solar-type star q 1 Eridani. This implies a Solar system-like architecture of the system, with an outer massive ‘Kuiper belt’, an inner ‘asteroid belt’, and a few Neptune- to Jupiter-mass planets in between.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
    Published by Oxford University Press
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  • 5
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    Rigging the deck: Selecting good problems for expert-novice card-sorting experiments (2012)
    American Physical Society (APS)
    Details
    Publication Date: 2012-11-13
    Description: Author(s): Steven F. Wolf, Daniel P. Dougherty, and Gerd Kortemeyer A seminal study by Chi et al. firmly established the paradigm that novices categorize physics problems by “surface features” (e.g., “incline,” “pendulum,” “projectile motion,” etc.), while experts use “deep structure” (e.g., “energy conservation,” “Newton 2,” etc.). Yet, efforts to replicate the stu... [Phys. Rev. ST Phys. Educ. Res. 8, 020116] Published Mon Nov 12, 2012
    Keywords: ARTICLES
    Electronic ISSN: 1554-9178
    Topics: Physics
    Published by American Physical Society (APS)
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  • 6
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    Empirical approach to interpreting card-sorting data (2012)
    American Physical Society (APS)
    Details
    Publication Date: 2012-05-19
    Description: Author(s): Steven F. Wolf, Daniel P. Dougherty, and Gerd Kortemeyer Since it was first published 30 years ago, the seminal paper of Chi et al. on expert and novice categorization of introductory problems led to a plethora of follow-up studies within and outside of the area of physics [ Cogn. Sci. 5 121 (1981) ]. These studies frequently encompass “card-sorting” exer... [Phys. Rev. ST Phys. Educ. Res. 8, 010124] Published Fri May 18, 2012
    Keywords: ARTICLES
    Electronic ISSN: 1554-9178
    Topics: Physics
    Published by American Physical Society (APS)
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  • 7
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    Geomicrobiology of subglacial ice above Lake Vostok, Antarctica (1999)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1999-12-11
    Description: Data from ice 3590 meters below Vostok Station indicate that the ice was accreted from liquid water associated with Lake Vostok. Microbes were observed at concentrations ranging from 2.8 x 10(3) to 3.6 x 10(4) cells per milliliter; no biological incorporation of selected organic substrates or bicarbonate was detected. Bacterial 16S ribosomal DNA genes revealed low diversity in the gene population. The phylotypes were closely related to extant members of the alpha- and beta-Proteobacteria and the Actinomycetes. Extrapolation of the data from accretion ice to Lake Vostok implies that Lake Vostok may support a microbial population, despite more than 10(6) years of isolation from the atmosphere.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Priscu, J C -- Adams, E E -- Lyons, W B -- Voytek, M A -- Mogk, D W -- Brown, R L -- McKay, C P -- Takacs, C D -- Welch, K A -- Wolf, C F -- Kirshtein, J D -- Avci, R -- New York, N.Y. -- Science. 1999 Dec 10;286(5447):2141-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Sciences, Montana State University, Bozeman, MT 59717, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10591642" target="_blank"〉PubMed〈/a〉
    Keywords: Antarctic Regions ; Bacteria/classification/genetics/*isolation & purification ; Bacterial Physiological Phenomena ; DNA, Bacterial/genetics/isolation & purification ; DNA, Ribosomal/genetics/isolation & purification ; Fresh Water/chemistry/*microbiology ; Genes, rRNA ; *Ice ; Microscopy, Electron, Scanning ; Microscopy, Fluorescence ; Minerals/analysis ; Pressure ; Proteobacteria/classification/genetics/isolation & purification/physiology ; RNA, Ribosomal, 16S/genetics ; Temperature ; Water Microbiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 8
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    The skeletal muscle chloride channel in dominant and recessive human myotonia (1992)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1992-08-07
    Description: Autosomal recessive generalized myotonia (Becker's disease) (GM) and autosomal dominant myotonia congenita (Thomsen's disease) (MC) are characterized by skeletal muscle stiffness that is a result of muscle membrane hyperexcitability. For both diseases, alterations in muscle chloride or sodium currents or both have been observed. A complementary DNA for a human skeletal muscle chloride channel (CLC-1) was cloned, physically localized on chromosome 7, and linked to the T cell receptor beta (TCRB) locus. Tight linkage of these two loci to GM and MC was found in German families. An unusual restriction site in the CLC-1 locus in two GM families identified a mutation associated with that disease, a phenylalanine-to-cysteine substitution in putative transmembrane domain D8. This suggests that different mutations in CLC-1 may cause dominant or recessive myotonia.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Koch, M C -- Steinmeyer, K -- Lorenz, C -- Ricker, K -- Wolf, F -- Otto, M -- Zoll, B -- Lehmann-Horn, F -- Grzeschik, K H -- Jentsch, T J -- New York, N.Y. -- Science. 1992 Aug 7;257(5071):797-800.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Medical Center for Human Genetics, Marburg University, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1379744" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Blotting, Southern ; Chloride Channels ; *Chromosomes, Human, Pair 7 ; Cloning, Molecular ; DNA/genetics ; Female ; *Genes, Dominant ; *Genes, Recessive ; Genetic Linkage ; Humans ; Ion Channels/*genetics ; Lod Score ; Male ; Membrane Proteins/*genetics ; Molecular Sequence Data ; Muscular Dystrophies/*genetics ; Myotonia Congenita/*genetics ; Pedigree ; Polymorphism, Restriction Fragment Length ; Receptors, Antigen, T-Cell/genetics ; Recombination, Genetic ; Sequence Homology, Nucleic Acid
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Asymmetric Michael Additions of 4-Hydroxycoumarin to β-Nitrostyrenes with Chiral, Bifunctional Hydrogen-Bonding Catalysts (2016)
    American Chemical Society (ACS)
    Details
    Publication Date: 2016-02-13
    Description: The Journal of Organic Chemistry DOI: 10.1021/acs.joc.5b02167
    Print ISSN: 0022-3263
    Electronic ISSN: 1520-6904
    Topics: Chemistry and Pharmacology
    Published by American Chemical Society (ACS)
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  • 10
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    Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro (1993)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1993-12-10
    Description: Peripheral blood mononuclear cells (PBMCs) from many asymptomatic individuals infected with human immunodeficiency virus-type 1 (HIV) are unresponsive as measured by in vitro T cell proliferation and interleukin-2 (IL-2) production to influenza virus and synthetic peptides of HIV envelope (Env). Strong influenza virus- and Env-stimulated IL-2 responses and T cell proliferation were restored when cultures were stimulated in the presence of IL-12. Interferon-gamma production by PBMCs from HIV seropositive (HIV+) patients was also restored with IL-12. Furthermore, in vitro antigen-specific production of IL-2 and proliferation of PBMCs from HIV- donors were suppressed by antibody to IL-12, but were not enhanced by addition of exogenous IL-12. Thus, IL-12 may be limiting in PBMCs from HIV+ but not HIV- individuals. These findings demonstrate that IL-12 can restore HIV-specific cell-mediated immunity in vitro in HIV-infected individuals and suggest a potential use of IL-12 in augmenting the diminished immunologic functions associated with HIV infection.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Clerici, M -- Lucey, D R -- Berzofsky, J A -- Pinto, L A -- Wynn, T A -- Blatt, S P -- Dolan, M J -- Hendrix, C W -- Wolf, S F -- Shearer, G M -- New York, N.Y. -- Science. 1993 Dec 10;262(5140):1721-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Experimental Immunology Branch, National Cancer Institute (NCI), National Institutes of Health (NIH), Bethesda, MD 20892.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7903123" target="_blank"〉PubMed〈/a〉
    Keywords: Cells, Cultured ; Gene Products, env/immunology ; HIV Infections/*immunology ; HIV-1/*immunology ; Humans ; Immunity, Cellular ; Influenza A virus/immunology ; Interferon-gamma/biosynthesis ; Interleukin-12 ; Interleukin-2/biosynthesis/pharmacology ; Interleukins/immunology/*pharmacology ; Killer Cells, Natural/immunology ; Leukocytes, Mononuclear/immunology ; Lymphocyte Activation ; Phytohemagglutinins/immunology ; Recombinant Proteins/pharmacology ; T-Lymphocytes, Helper-Inducer/*immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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