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  • 1
    Publication Date: 2019
    Description: 〈p〉Wearable human-machine interfaces (HMIs) are an important class of devices that enable human and machine interaction and teaming. Recent advances in electronics, materials, and mechanical designs have offered avenues toward wearable HMI devices. However, existing wearable HMI devices are uncomfortable to use and restrict the human body’s motion, show slow response times, or are challenging to realize with multiple functions. Here, we report sol-gel-on-polymer–processed indium zinc oxide semiconductor nanomembrane–based ultrathin stretchable electronics with advantages of multifunctionality, simple manufacturing, imperceptible wearing, and robust interfacing. Multifunctional wearable HMI devices range from resistive random-access memory for data storage to field-effect transistors for interfacing and switching circuits, to various sensors for health and body motion sensing, and to microheaters for temperature delivery. The HMI devices can be not only seamlessly worn by humans but also implemented as prosthetic skin for robotics, which offer intelligent feedback, resulting in a closed-loop HMI system.〈/p〉
    Electronic ISSN: 2375-2548
    Topics: Natural Sciences in General
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  • 2
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    Oxford University Press
    Publication Date: 2015-05-24
    Description: We propose a method of effective dimension reduction for functional data, emphasizing the sparse design where one observes only a few noisy and irregular measurements for some or all of the subjects. The proposed method borrows strength across the entire sample and provides a way to characterize the effective dimension reduction space, via functional cumulative slicing. Our theoretical study reveals a bias-variance trade-off associated with the regularizing truncation and decaying structures of the predictor process and the effective dimension reduction space. A simulation study and an application illustrate the superior finite-sample performance of the method.
    Print ISSN: 0006-3444
    Electronic ISSN: 1464-3510
    Topics: Biology , Mathematics , Medicine
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  • 3
    Publication Date: 2014-05-21
    Description: The giant X-ray bump of GRB 121027A observed by Swift is different from the typical X-ray flares in gamma-ray bursts. The observed structural variability in the rise and decay phases of the bump has four components. Of these four components, only the data in the bump from about 5300 to about 6100 s is of good enough quality to be analysed using the stepwise filter correlation method. A $86^{+5.9}_{-9.4} \rm s$ periodic oscillation is postulated, which is confirmed by the Lomb–Scargle method. A jet precession model is proposed to account for this variability.
    Print ISSN: 0035-8711
    Electronic ISSN: 1365-2966
    Topics: Physics
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  • 4
    Publication Date: 2015-06-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zhang, Guojie -- Rahbek, Carsten -- Graves, Gary R -- Lei, Fumin -- Jarvis, Erich D -- Gilbert, M Thomas P -- England -- Nature. 2015 Jun 4;522(7554):34. doi: 10.1038/522034d.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉China National GeneBank, BGI-Shenzhen, China.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/26040883" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Birds/*genetics/virology ; Genome/*genetics ; Genomics/*trends ; Zoonoses/virology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2005-07-08
    Description: H5N1 avian influenza virus (AIV) has emerged as a pathogenic entity for a variety of species, including humans, in recent years. Here we report an outbreak among migratory birds on Lake Qinghaihu, China, in May and June 2005, in which more than a thousand birds were affected. Pancreatic necrosis and abnormal neurological symptoms were the major clinical features. Sequencing of the complete genomes of four H5N1 AIV strains revealed them to be reassortants related to a peregrine falcon isolate from Hong Kong and to have known highly pathogenic characteristics. Experimental animal infections reproduced typical highly pathogenic AIV infection symptoms and pathology.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Liu, J -- Xiao, H -- Lei, F -- Zhu, Q -- Qin, K -- Zhang, X-W -- Zhang, X-L -- Zhao, D -- Wang, G -- Feng, Y -- Ma, J -- Liu, W -- Wang, J -- Gao, G F -- New York, N.Y. -- Science. 2005 Aug 19;309(5738):1206. Epub 2005 Jul 6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉College of Veterinary Medicine, China Agricultural University, Beijing 100094, China. jhl@cau.edu.cn〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16000410" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animal Migration ; Animals ; Birds/virology ; Charadriiformes/*virology ; Chickens ; China/epidemiology ; Disease Outbreaks/*veterinary ; Geese/*virology ; Genome, Viral ; *Influenza A Virus, H5N1 Subtype ; Influenza A virus/classification/genetics/isolation & purification/*pathogenicity ; Influenza in Birds/*epidemiology/pathology/*virology ; Mice ; Molecular Sequence Data ; Phylogeny ; Reassortant Viruses/genetics/pathogenicity ; Virulence
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 2013-11-03
    Description: Langmuir DOI: 10.1021/la4027859
    Print ISSN: 0743-7463
    Electronic ISSN: 1520-5827
    Topics: Chemistry and Pharmacology
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  • 7
    Publication Date: 2018-08-31
    Description: In this paper, the cultivars of Pinus koraiensis and Japanese larch varieties in Liaoning Province were studied. Aiming to solve the problem of data update difficulty and lack of information management, the Kriging interpolation method and UAV (Unmanned Aerial Vehicles) and GPS technology positioning method were used for fine positioning of the improved varieties of forest seed base. Using linear comparison and distributed comparison method for accuracy assessment, 100 Pinus koraiensises were sampled by liner comparison method among which 10 were selected to be tested by distribution comparison method. With the help of the high density total station, the samples were measured and analyzed by the coordination. It showed the positioning accuracy was less than 1m, which met the need of the production of the forest seed base. On this basis, the tree seed production management information base database was established and the database structure design and structure design was made. T...
    Print ISSN: 1755-1307
    Electronic ISSN: 1755-1315
    Topics: Geography , Geosciences , Physics
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  • 8
    Publication Date: 2016-01-09
    Description: Azinomycin B is a hybrid polyketide/nonribosomal peptide natural product and possesses antitumor activity by interacting covalently with duplex DNA and inducing interstrand crosslinks. In the biosynthetic study of azinomycin B, a gene ( orf1 ) adjacent to the azinomycin B gene cluster was found to be essential for the survival of the producer, Streptomyces sahachiroi ATCC33158. Sequence analyses revealed that Orf1 belongs to the HTH_42 superfamily of conserved bacterial proteins which are widely distributed in pathogenic and antibiotic-producing bacteria with unknown functions. The protein exhibits a protective effect against azinomycin B when heterologously expressed in azinomycin-sensitive strains. EMSA assays showed its sequence nonspecific binding to DNA and structure-specific binding to azinomycin B-adducted sites, and ChIP assays revealed extensive association of Orf1 with chromatin in vivo . Interestingly, Orf1 not only protects target sites by protein–DNA interaction but is also capable of repairing azinomycin B-mediated DNA cross-linking. It possesses the DNA glycosylase-like activity and specifically repairs DNA damage induced by azinomycin B through removal of both adducted nitrogenous bases in the cross-link. This bifunctional protein massively binds to genomic DNA to reduce drug attack risk as a novel DNA binding protein and triggers the base excision repair system as a novel DNA glycosylase.
    Print ISSN: 0305-1048
    Electronic ISSN: 1362-4962
    Topics: Biology
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  • 9
    Publication Date: 2017-06-22
    Description: In this work, we have succeeded in obtaining high quality warm w -LEDs by adopting hybrid two-dimensional (2D) structure of SiN x photonic crystal layer (PCL) assisted cyan-emitting ceramic-plate thiosilicate SrLa 2 Si 2 S 8 :Ce 3+ with red-emitting film SrLiAl 3 N 4 :Eu 2+ phosphor on a 430 nm blue LED chip at 350 mA. 2D SiN x PCL was capped with thiosilicate is because it can enhance the luminous efficacy and maintain the low correlated color temperature (CCT) and high color-rendering index (CRI). High luminous efficacy (82.3 lm/W), high special CRI (R 9 = 75) as well as the low CCT (5431 K) of the optimal w -LED was obtained due to the assistances of 2D SiN x PCL and narrow-band red-emitting phosphor with the doping percentage at 10 wt%. The synthesis processes, structural analysis, optical properties and LED device performances were detailed investigated to find out the relationship between the optimum composition and good optical properties. Based on intriguing luminescence properties by the 2D SiN x PCL and red-emitting film phosphor introducing, we proclaim this method could also have high potential application in other phosphor-converted w -LEDs. This article is protected by copyright. All rights reserved.
    Print ISSN: 0002-7820
    Electronic ISSN: 1551-2916
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Published by Wiley
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  • 10
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 79 (2001), S. 2489-2491 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Near-field fluorescence spectra with subdiffraction limit spatial resolution have been taken in the proximity of mitochondrial membrane inside breast adenocarcinoma cells (MCF7) treated with the fluorescent dye (JC-1) by using a scanning near-field optical microscope coupled with a confocal laser microspectrofluorometer. The probe–sample distance control is based on a piezoelectric bimorph shear force sensor having a static spring constant k=5 μN/nm and a quality factor Q=40 in a physiological medium of viscosity η=1.0 cp. The sensitivity of the force sensor has been tested by imaging a MCF7 cell surface. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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