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  • 1
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1990-04-06
    Description: Neurons with oscillatory properties are a common feature of the nervous system, but little is known about how neural oscillators shape the behavior of neuronal networks or how network interactions influence the properties of neural oscillators. Mathematical models are used to examine the effect of electrically coupling an oscillatory neuron to a second neuron that is either silent or tonically firing. Models of oscillatory neurons with varying degrees of complexity show that this coupling can either increase or decrease the frequency of an oscillator, depending on its membrane potential wave form, the state of the neuron to which it is coupled, and the strength of the coupling. Thus, electrical coupling provides a flexible mechanism for modifying the behavior of an oscillatory neural network.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kepler, T B -- Marder, E -- Abbott, L F -- NS17813/NS/NINDS NIH HHS/ -- T32NS07292/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1990 Apr 6;248(4951):83-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biology, Brandeis University, Waltham, MA 02254.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2321028" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials ; Biological Clocks ; Electric Conductivity ; Electrophysiology ; Mathematics ; Membrane Potentials ; *Models, Biological ; Neurons/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2005-11-08
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bullock, Theodore H -- Bennett, Michael V L -- Johnston, Daniel -- Josephson, Robert -- Marder, Eve -- Fields, R Douglas -- New York, N.Y. -- Science. 2005 Nov 4;310(5749):791-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Scripps Institution of Oceanography and Department of Neuroscience, University of California, San Diego, La Jolla, CA 92093, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16272104" target="_blank"〉PubMed〈/a〉
    Keywords: Action Potentials ; Animals ; Astrocytes/physiology ; Axons/physiology ; Brain/*physiology ; Cell Communication ; Dendrites/physiology ; Gap Junctions/physiology ; Humans ; *Nervous System Physiological Phenomena ; Neuroglia/physiology ; Neurons/cytology/*physiology ; Neurotransmitter Agents/physiology ; Synapses/physiology ; Synaptic Transmission
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1993-03-26
    Description: Neurons maintain their electrical activity patterns despite channel turnover, cell growth, and variable extracellular conditions. A model is presented in which maximal conductances of ionic currents depend on the intracellular concentration of calcium ions and so, indirectly, on activity. Model neurons with activity-dependent maximal conductances modify their conductances to maintain a given behavior when perturbed. Moreover, neurons that are described by identical sets of equations can develop different properties in response to different patterns of presynaptic activity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉LeMasson, G -- Marder, E -- Abbott, L F -- MH46742/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 1993 Mar 26;259(5103):1915-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biology, Brandeis University, Waltham, MA 02254.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8456317" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Calcium/*metabolism/pharmacology ; Electric Conductivity ; Electric Stimulation ; Feedback ; *Models, Biological ; Neurons/drug effects/*physiology ; Potassium/metabolism/pharmacology ; Second Messenger Systems ; Sodium/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1994-05-13
    Description: Learning and memory arise through activity-dependent modifications of neural circuits. Although the activity dependence of synaptic efficacy has been studied extensively, less is known about how activity shapes the intrinsic electrical properties of neurons. Lobster stomatogastric ganglion neurons fire in bursts when receiving synaptic and modulatory input but fire tonically when pharmacologically isolated. Long-term isolation in culture changed their intrinsic activity from tonic firing to burst firing. Rhythmic stimulation reversed this transition through a mechanism that was mediated by a rise in intracellular calcium concentration. These data suggest that neurons regulate their conductances to maintain stable activity patterns and that the intrinsic properties of a neuron depend on its recent history of activation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Turrigiano, G -- Abbott, L F -- Marder, E -- MH46742/MH/NIMH NIH HHS/ -- NS17813/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1994 May 13;264(5161):974-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biology, Brandeis University, Waltham, MA 02254.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8178157" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Calcium/physiology ; Cells, Cultured ; Egtazic Acid/analogs & derivatives/pharmacology ; Electric Stimulation ; Electrophysiology ; Ganglia, Invertebrate/cytology ; Membrane Potentials ; Nephropidae ; Neurites/physiology ; Neurons/cytology/*physiology ; Synapses/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2013-04-27
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Birren, Susan J -- Marder, Eve -- New York, N.Y. -- Science. 2013 Apr 26;340(6131):436-7. doi: 10.1126/science.1238518.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Biology Department and Volen Center, Brandeis University, Waltham, MA 02454, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23620040" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenal Cortex Hormones/blood ; Animals ; Anxiety/blood/physiopathology ; Corticotropin-Releasing Hormone/*secretion ; Depression/blood/physiopathology ; Dopamine/*secretion ; Humans ; Hypothalamus/cytology/*physiology/secretion ; *Neuronal Plasticity ; Neurons/secretion ; *Photoperiod ; Rats ; Signal Transduction ; Somatostatin/*secretion ; Stress, Psychological/blood/physiopathology ; *Synaptic Transmission
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 2014-04-26
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉O'Leary, Timothy -- Marder, Eve -- New York, N.Y. -- Science. 2014 Apr 25;344(6182):372-3. doi: 10.1126/science.1253853.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Volen Center and Biology Department, Brandeis University, Waltham, MA 02453, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24763581" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Behavior, Animal ; Drosophila melanogaster/*physiology ; Neurons/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    Unknown
    American Association for the Advancement of Science (AAAS)
    Publication Date: 1982-09-03
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Marder, E -- New York, N.Y. -- Science. 1982 Sep 3;217(4563):924-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17747950" target="_blank"〉PubMed〈/a〉
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Neuroscience 14 (1991), S. 39-57 
    ISSN: 0147-006X
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Pharmacology 16 (1976), S. 245-268 
    ISSN: 0362-1642
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 73 (1951), S. 5475-5476 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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