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  • 1
    Publication Date: 2015-10-21
    Description: Author(s): J. M. Yao (尧江明), E. F. Zhou (周恩付), and Z. P. Li (李志攀) We report the first beyond-mean-field study of low-lying parity-doublet states in Ra 224 by extending the multireference relativistic energy density functional method to include dynamical correlations related to symmetry restoration and quadrupole-octupole shape fluctuation with a generator coordinat… [Phys. Rev. C 92, 041304(R)] Published Tue Oct 20, 2015
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
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  • 2
    Publication Date: 2011-11-04
    Description: Author(s): Z. P. Li, J. M. Yao, D. Vretenar, T. Nikšić, H. Chen, and J. Meng [Phys. Rev. C 84, 054304] Published Thu Nov 03, 2011
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
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  • 3
    Publication Date: 2012-02-29
    Description: Author(s): N. Hinohara, Z. P. Li, T. Nakatsukasa, T. Nikšić, and D. Vretenar Most current implementations of the quadrupole collective Hamiltonian model do not include the contributions of time-odd mean fields to the moments of inertia and mass parameters (Thouless-Valatin dynamical rearrangement contributions). A hybrid model is introduced that allows a quantitative estimat... [Phys. Rev. C 85, 024323] Published Tue Feb 28, 2012
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
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  • 4
    Publication Date: 2014-05-06
    Description: Author(s): J. M. Yao, K. Hagino, Z. P. Li, J. Meng, and P. Ring We report on a seven-dimensional generator coordinate calculation in the two deformation parameters β and γ together with projection on three-dimensional angular momentum and two particle numbers for the low-lying states in 76Kr. These calculations are based on covariant density functional theory. E... [Phys. Rev. C 89, 054306] Published Mon May 05, 2014
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
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  • 5
    Publication Date: 2014-01-30
    Description: Author(s): X. Y. Wu (吴先业), J. M. Yao (尧江明), and Z. P. Li (李志攀) The low-energy structure of 46Ar is of particular interest due to the possible coexistence of different shapes and the possible existence of proton “bubble” structures. In this work, we apply a beyond relativistic mean-field approach to study the low-energy structure of 46Ar. Correlations beyond the... [Phys. Rev. C 89, 017304] Published Wed Jan 29, 2014
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
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  • 6
    Publication Date: 2012-03-21
    Description: Author(s): H. Mei (梅花), J. Xiang (向剑), J. M. Yao (尧江明), Z. P. Li (李志攀), and J. Meng (孟杰) The rapid structural change in low-lying collective excitation states of neutron-rich Sr and Zr isotopes is studied by solving a five-dimensional collective Hamiltonian with parameters determined from both relativistic mean-field and nonrelativistic Skyrme-Hartree-Fock calculations using the PC-PK1 ... [Phys. Rev. C 85, 034321] Published Tue Mar 20, 2012
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
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  • 7
    Publication Date: 2015-02-25
    Description: Author(s): K. Q. Lu, Z. X. Li, Z. P. Li, J. M. Yao, and J. Meng We report the first global study of dynamic correlation energies (DCEs) associated with rotational motion and quadrupole shape vibrational motion in a covariant energy density functional (CEDF) for 575 even-even nuclei with proton numbers ranging from Z=8 to Z=108 by solving a five-dimensional colle... [Phys. Rev. C 91, 027304] Published Tue Feb 24, 2015
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
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  • 8
    Publication Date: 2011-08-11
    Description: Author(s): J. M. Yao, J. Meng, P. Ring, Z. X. Li, Z. P. Li, and K. Hagino Covariant density functional theory is used to investigate quantum shape fluctuation in 16 C and other even-even carbon isotopes. Long-range correlations beyond the mean-field approximation are taken into account by configuration mixing of wave functions with triaxial shapes and by restoring the spon... [Phys. Rev. C 84, 024306] Published Wed Aug 10, 2011
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
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  • 9
    Publication Date: 2001-03-07
    Description: Little is known about the innate defense mechanisms of the male reproductive tract. We cloned a 385-base pair complementary DNA and its genomic DNA named Bin1b that is exclusively expressed in the caput region of the rat epididymis and that is responsible for sperm maturation, storage, and protection. Bin1b exhibits structural characteristics and antimicrobial activity similar to that of cationic antimicrobial peptides, beta-defensins. Bin1b is maximally expressed when the rats are sexually mature and can be up-regulated by inflammation. Bin1b appears to be a natural epididymis-specific antimicrobial peptide that plays a role in reproductive tract host defense and male fertility.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Li, P -- Chan, H C -- He, B -- So, S C -- Chung, Y W -- Shang, Q -- Zhang, Y D -- Zhang, Y L -- New York, N.Y. -- Science. 2001 Mar 2;291(5509):1783-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 320, Yue-Yang Road, Shanghai 200031, China.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11230693" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cells, Cultured ; Cloning, Molecular ; DNA, Complementary ; Epididymis/*immunology/physiology ; Epididymitis/immunology ; Escherichia coli/growth & development ; Gene Expression Profiling ; Gene Expression Regulation, Developmental ; Genes ; Humans ; Male ; Molecular Sequence Data ; Oligonucleotides, Antisense/pharmacology ; RNA, Messenger/genetics/metabolism ; Rats ; Rats, Sprague-Dawley ; Sequence Alignment ; Sexual Maturation ; Spermatozoa/physiology ; Up-Regulation ; beta-Defensins/chemistry/*genetics/pharmacology/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
    Publication Date: 2010-08-13
    Description: The use of homologous recombination to modify genes in embryonic stem (ES) cells provides a powerful means to elucidate gene function and create disease models. Application of this technology to engineer genes in rats has not previously been possible because of the absence of germline-competent ES cells in this species. We have recently established authentic rat ES cells. Here we report the generation of gene knockout rats using the ES-cell-based gene targeting technology. We designed a targeting vector to disrupt the tumour suppressor gene p53 (also known as Tp53) in rat ES cells by means of homologous recombination. p53 gene-targeted rat ES cells can be routinely generated. Furthermore, the p53 gene-targeted mutation in the rat ES-cell genome can transmit through the germ line via ES-cell rat chimaeras to create p53 gene knockout rats. The rat is the most widely used animal model in biological research. The establishment of gene targeting technology in rat ES cells, in combination with advances in genomics and the vast amount of research data on physiology and pharmacology in this species, now provide a powerful new platform for the study of human disease.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937076/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937076/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Tong, Chang -- Li, Ping -- Wu, Nancy L -- Yan, Youzhen -- Ying, Qi-Long -- 1R01 RR025881/RR/NCRR NIH HHS/ -- R01 OD010926/OD/NIH HHS/ -- R01 RR025881/RR/NCRR NIH HHS/ -- R01 RR025881-01A2/RR/NCRR NIH HHS/ -- England -- Nature. 2010 Sep 9;467(7312):211-3. doi: 10.1038/nature09368. Epub 2010 Aug 11.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, Department of Cell and Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20703227" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; Cell Culture Techniques ; Embryo, Mammalian/cytology ; Embryonic Stem Cells/*cytology ; Female ; Gene Knockout Techniques/*methods ; *Genes, p53 ; Germ-Line Mutation ; Male ; Mice ; Molecular Sequence Data ; Rats/*genetics ; Rats, Inbred F344 ; Rats, Sprague-Dawley ; Recombination, Genetic
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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