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  • Nuclear Structure  (4)
  • Electronic structure and strongly correlated systems  (3)
  • Transfection  (3)
  • 1
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    Ab initio nuclear many-body perturbation calculations in the Hartree-Fock basis (2016)
    American Physical Society (APS)
    Details
    Publication Date: 2016-07-07
    Description: Author(s): B. S. Hu (胡柏山), F. R. Xu (许甫荣), Z. H. Sun (孙中浩), J. P. Vary, and T. Li (李通) Starting from realistic nuclear forces, the chiral N 3 LO and JISP16, we have applied many-body perturbation theory (MBPT) to the structure of closed-shell nuclei, He 4 and O 16 . The two-body N 3 LO interaction is softened by a similarity renormalization group transformation while JISP16 is adopted withou… [Phys. Rev. C 94, 014303] Published Wed Jul 06, 2016
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
    Published by American Physical Society (APS)
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  • 2
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    Activity-dependent regulation of inhibitory synapse development by Npas4 (2008)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2008-09-26
    Description: Neuronal activity regulates the development and maturation of excitatory and inhibitory synapses in the mammalian brain. Several recent studies have identified signalling networks within neurons that control excitatory synapse development. However, less is known about the molecular mechanisms that regulate the activity-dependent development of GABA (gamma-aminobutyric acid)-releasing inhibitory synapses. Here we report the identification of a transcription factor, Npas4, that plays a role in the development of inhibitory synapses by regulating the expression of activity-dependent genes, which in turn control the number of GABA-releasing synapses that form on excitatory neurons. These findings demonstrate that the activity-dependent gene program regulates inhibitory synapse development, and suggest a new role for this program in controlling the homeostatic balance between synaptic excitation and inhibition.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637532/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637532/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lin, Yingxi -- Bloodgood, Brenda L -- Hauser, Jessica L -- Lapan, Ariya D -- Koon, Alex C -- Kim, Tae-Kyung -- Hu, Linda S -- Malik, Athar N -- Greenberg, Michael E -- HD18655/HD/NICHD NIH HHS/ -- NS27572/NS/NINDS NIH HHS/ -- NS48276/NS/NINDS NIH HHS/ -- P01 NS047572/NS/NINDS NIH HHS/ -- P01 NS047572-01A10001/NS/NINDS NIH HHS/ -- P01 NS047572-020001/NS/NINDS NIH HHS/ -- P01 NS047572-030001/NS/NINDS NIH HHS/ -- P01 NS047572-040001/NS/NINDS NIH HHS/ -- P01 NS047572-050001/NS/NINDS NIH HHS/ -- R01 MH091220/MH/NIMH NIH HHS/ -- R01 NS048276/NS/NINDS NIH HHS/ -- R01 NS048276-01/NS/NINDS NIH HHS/ -- R01 NS048276-02/NS/NINDS NIH HHS/ -- R01 NS048276-03/NS/NINDS NIH HHS/ -- R01 NS048276-04/NS/NINDS NIH HHS/ -- R01 NS048276-05/NS/NINDS NIH HHS/ -- T32 GM007753/GM/NIGMS NIH HHS/ -- England -- Nature. 2008 Oct 30;455(7217):1198-204. doi: 10.1038/nature07319. Epub 2008 Sep 24.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉F. M. Kirby Neurobiology Center, Children's Hospital and Department of Neurology, Harvard Medical School, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18815592" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics/*metabolism ; Brain-Derived Neurotrophic Factor/metabolism ; Cells, Cultured ; Electrophysiology ; Gene Expression Regulation ; Hippocampus/cytology ; Mice ; Neurons/metabolism ; Rats ; Synapses/*metabolism ; Transcription Factors/genetics/*metabolism ; Transfection ; gamma-Aminobutyric Acid/metabolism
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
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  • 3
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    Retroviral recombination and reverse transcription (1990)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1990-11-30
    Description: Recombination occurs at a high rate in retroviral replication, and its observation requires a virion containing two different RNA molecules (heterodimeric particles). Analysis of retroviral recombinants formed after a single round of replication revealed that (i) the nonselected markers changed more frequently than expected from the rate of recombination of selected markers; (ii) the transfer of the initially synthesized minus strand strong stop DNA was either intramolecular or intermolecular; (iii) the transfer of the first synthesized plus strand strong stop DNA was always intramolecular; and (iv) there was a strong correlation between the type of transfer of the minus strand strong stop DNA and the number of template switches observed. These data suggest that retroviral recombination is ordered and occurs during the synthesis of both minus and plus strand DNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hu, W S -- Temin, H M -- CA-07175/CA/NCI NIH HHS/ -- CA-22443/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 1990 Nov 30;250(4985):1227-33.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉McArdle Laboratory for Cancer Research, University of Wisconsin-Madison 53706.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1700865" target="_blank"〉PubMed〈/a〉
    Keywords: Biological Evolution ; DNA, Viral/biosynthesis/genetics ; Drug Resistance/genetics ; Genetic Vectors ; Neomycin ; Osteosarcoma ; RNA, Viral/genetics ; RNA-Directed DNA Polymerase ; *Recombination, Genetic ; Repetitive Sequences, Nucleic Acid ; Restriction Mapping ; Retroviridae/*genetics/physiology ; T-Lymphocytes, Helper-Inducer/microbiology ; Templates, Genetic ; *Transcription, Genetic ; Transfection ; Tumor Cells, Cultured ; Virion/genetics ; Virus Replication
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number (2006)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2006-02-18
    Description: In the mammalian nervous system, neuronal activity regulates the strength and number of synapses formed. The genetic program that coordinates this process is poorly understood. We show that myocyte enhancer factor 2 (MEF2) transcription factors suppressed excitatory synapse number in a neuronal activity- and calcineurin-dependent manner as hippocampal neurons formed synapses. In response to increased neuronal activity, calcium influx into neurons induced the activation of the calcium/calmodulin-regulated phosphatase calcineurin, which dephosphorylated and activated MEF2. When activated, MEF2 promoted the transcription of a set of genes, including arc and synGAP, that restrict synapse number. These findings define an activity-dependent transcriptional program that may control synapse number during development.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Flavell, Steven W -- Cowan, Christopher W -- Kim, Tae-Kyung -- Greer, Paul L -- Lin, Yingxi -- Paradis, Suzanne -- Griffith, Eric C -- Hu, Linda S -- Chen, Chinfei -- Greenberg, Michael E -- AG05870/AG/NIA NIH HHS/ -- HD18655/HD/NICHD NIH HHS/ -- NS28829/NS/NINDS NIH HHS/ -- R01 EY013613/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 2006 Feb 17;311(5763):1008-12.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Neurobiology Program, Children's Hospital, and Departments of Neurology and Neurobiology, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/16484497" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Calcineurin/metabolism ; Calcium/metabolism ; Cells, Cultured ; Cytoskeletal Proteins/genetics ; Dendrites/physiology/ultrastructure ; Excitatory Postsynaptic Potentials ; GTPase-Activating Proteins/genetics ; Gene Expression Regulation ; Glutamic Acid/metabolism ; Hippocampus/cytology/*physiology ; MEF2 Transcription Factors ; Mutation ; Myogenic Regulatory Factors/genetics/*physiology ; Nerve Tissue Proteins/genetics ; Neurons/*physiology ; Oligonucleotide Array Sequence Analysis ; Phosphorylation ; RNA Interference ; Rats ; Rats, Long-Evans ; Recombinant Fusion Proteins/metabolism ; Synapses/*physiology ; Synaptic Transmission ; Transcription, Genetic ; Transfection
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Gogny-force-derived effective shell-model Hamiltonian (2018)
    American Physical Society (APS)
    Details
    Publication Date: 2018-10-26
    Description: Author(s): W. G. Jiang, B. S. Hu, Z. H. Sun, and F. R. Xu The density-dependent finite-range Gogny force has been used to derive the effective Hamiltonian for the shell-model calculations of nuclei. The density dependence simulates an equivalent three-body force, while the finite range gives a Gaussian distribution of the interaction in the momentum space ... [Phys. Rev. C 98, 044320] Published Thu Oct 25, 2018
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
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  • 6
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    Chiral ${\mathrm{NNLO}}_{\mathrm{sat}}$ descriptions of nuclear multipole resonances within the random-phase approximation (2018)
    American Physical Society (APS)
    Details
    Publication Date: 2018-05-04
    Description: Author(s): Q. Wu, B. S. Hu, F. R. Xu, Y. Z. Ma, S. J. Dai, Z. H. Sun, and G. R. Jansen We study nuclear multipole resonances in the framework of the random-phase approximation by using the chiral potential NNLO sat . This potential includes two- and three-body terms that have been simultaneously optimized to low-energy nucleon-nucleon scattering data and selected nuclear structure data.... [Phys. Rev. C 97, 054306] Published Thu May 03, 2018
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
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  • 7
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    Brueckner-Hartree-Fock calculations for finite nuclei with renormalized realistic forces (2017)
    American Physical Society (APS)
    Details
    Publication Date: 2017-03-28
    Description: Author(s): B. S. Hu (胡柏山), F. R. Xu (许甫荣), Q. Wu (吴强), Y. Z. Ma (马远卓), and Z. H. Sun (孙中浩) One can adopt two-step G -matrix approximations for the Brueckner-Hartree-Fock (BHF) calculations. The first G matrix is to soften the bare force, and the second one is to include the high-order correlations of the interaction in medium. The first G -matrix calculation for two-nucleon interaction shou… [Phys. Rev. C 95, 034321] Published Mon Mar 27, 2017
    Keywords: Nuclear Structure
    Print ISSN: 0556-2813
    Electronic ISSN: 1089-490X
    Topics: Physics
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  • 8
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    Broadband terahertz spectroscopy of the insulator-metal transition driven by coherent lattice deformation at the SmNiO_{3} /LaAlO_{3} interface (2016)
    American Physical Society (APS)
    Details
    Publication Date: 2016-04-13
    Description: Author(s): W. Hu, S. Catalano, M. Gibert, J.-M. Triscone, and A. Cavalleri We investigate the nonequilibrium insulator-metal transition driven in a SmNi O 3 thin film by coherent optical excitation of the LaAl O 3 substrate lattice. By probing the transient optical properties over a broad frequency range ( 100 − 800 c m − 1 ) , we analyze both the time-dependent metallic plasma and the… [Phys. Rev. B 93, 161107(R)] Published Tue Apr 12, 2016
    Keywords: Electronic structure and strongly correlated systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
    Published by American Physical Society (APS)
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  • 9
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    Crystal field ground state of the orthorhombic Kondo semiconductors CeOs_{2}Al_{10} and CeFe_{2}Al_{10} (2013)
    American Physical Society (APS)
    Details
    Publication Date: 2013-03-15
    Description: Author(s): F. Strigari, T. Willers, Y. Muro, K. Yutani, T. Takabatake, Z. Hu, S. Agrestini, C.-Y. Kuo, Y.-Y. Chin, H.-J. Lin, T. W. Pi, C. T. Chen, E. Weschke, E. Schierle, A. Tanaka, M. W. Haverkort, L. H. Tjeng, and A. Severing Here we present linear-polarization-dependent soft x-ray absorption spectroscopy data at the Ce M 4,5 edges of CeOs 2 Al 10 and CeFe 2 Al 10 . Despite the strong hybridization between 4 f and conduction electrons and the existence of spin gaps as seen in inelastic neutron scattering, we were able to determin... [Phys. Rev. B 87, 125119] Published Thu Mar 14, 2013
    Keywords: Electronic structure and strongly correlated systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
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  • 10
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    Valley-degenerate two-dimensional electrons in the lowest Landau level (2014)
    American Physical Society (APS)
    Details
    Publication Date: 2014-01-18
    Description: Author(s): Tomasz M. Kott, Binhui Hu, S. H. Brown, and B. E. Kane We report low temperature magnetotransport measurements on a high mobility (μ=325000cm2/Vs) two-dimensional electron system on a H-terminated Si(111) surface. We observe the integral quantum Hall effect at all filling factors ν≤6 and find that ν=2 develops in an unusually narrow temperature range. A... [Phys. Rev. B 89, 041107] Published Fri Jan 17, 2014
    Keywords: Electronic structure and strongly correlated systems
    Print ISSN: 1098-0121
    Electronic ISSN: 1095-3795
    Topics: Physics
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