Publication Date:
2000-01-29
Description:
Recognition of a specific visual target among equally familiar distracters requires neural mechanisms for tracking items in working memory. Event-related functional magnetic resonance imaging revealed evidence for two such mechanisms: (i) Enhanced neural responses, primarily in the frontal cortex, were associated with the target and were maintained across repetitions of the target. (ii) Reduced responses, primarily in the extrastriate visual cortex, were associated with stimulus repetition, regardless of whether the stimulus was a target or a distracter. These complementary neural mechanisms track the status of familiar items in working memory, allowing for the efficient recognition of a currently relevant object and rejection of irrelevant distracters.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jiang, Y -- Haxby, J V -- Martin, A -- Ungerleider, L G -- Parasuraman, R -- AG07569/AG/NIA NIH HHS/ -- New York, N.Y. -- Science. 2000 Jan 28;287(5453):643-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD 20892-1366, USA. yjiang@codon.nih.gov〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10649996" target="_blank"〉PubMed〈/a〉
Keywords:
Cerebral Cortex/anatomy & histology/*physiology
;
Face
;
Frontal Lobe/anatomy & histology/*physiology
;
Humans
;
Magnetic Resonance Imaging
;
Memory/*physiology
;
Regression Analysis
;
Visual Cortex/anatomy & histology/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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