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  • Adsorption  (1)
  • Entropy  (1)
  • American Association for the Advancement of Science (AAAS)  (2)
  • 1
    Publication Date: 2002-11-02
    Description: We present an approach to fabricate solid capsules with precise control of size, permeability, mechanical strength, and compatibility. The capsules are fabricated by the self-assembly of colloidal particles onto the interface of emulsion droplets. After the particles are locked together to form elastic shells, the emulsion droplets are transferred to a fresh continuous-phase fluid that is the same as that inside the droplets. The resultant structures, which we call "colloidosomes," are hollow, elastic shells whose permeability and elasticity can be precisely controlled. The generality and robustness of these structures and their potential for cellular immunoisolation are demonstrated by the use of a variety of solvents, particles, and contents.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dinsmore, A D -- Hsu, Ming F -- Nikolaides, M G -- Marquez, Manuel -- Bausch, A R -- Weitz, D A -- New York, N.Y. -- Science. 2002 Nov 1;298(5595):1006-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics and DEAS, Harvard University, Cambridge, MA 02138, USA. dinsmore@physics.umass.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12411700" target="_blank"〉PubMed〈/a〉
    Keywords: Adsorption ; *Capsules ; Cell Physiological Phenomena ; Cell Survival ; Cells, Cultured ; Chemistry, Physical ; *Colloids ; Diffusion ; Elasticity ; Emulsions ; Fibroblasts/physiology ; Microscopy, Confocal ; Microscopy, Electron, Scanning ; Permeability ; Physicochemical Phenomena ; Polylysine ; Polymethyl Methacrylate ; Surface Properties ; Water
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2004-05-29
    Description: Networks of cross-linked and bundled actin filaments are ubiquitous in the cellular cytoskeleton, but their elasticity remains poorly understood. We show that these networks exhibit exceptional elastic behavior that reflects the mechanical properties of individual filaments. There are two distinct regimes of elasticity, one reflecting bending of single filaments and a second reflecting stretching of entropic fluctuations of filament length. The mechanical stiffness can vary by several decades with small changes in cross-link concentration, and can increase markedly upon application of external stress. We parameterize the full range of behavior in a state diagram and elucidate its origin with a robust model.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gardel, M L -- Shin, J H -- MacKintosh, F C -- Mahadevan, L -- Matsudaira, P -- Weitz, D A -- GM52703/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2004 May 28;304(5675):1301-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physics, Harvard University, Cambridge, MA 02138, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15166374" target="_blank"〉PubMed〈/a〉
    Keywords: Actin Cytoskeleton/*chemistry/metabolism ; Actins/*chemistry/metabolism ; Biopolymers/chemistry/metabolism ; Elasticity ; Entropy ; Mathematics ; Microfilament Proteins/chemistry/metabolism ; Models, Biological ; Stress, Mechanical
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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