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  • METEOROLOGY AND CLIMATOLOGY  (25)
  • LUNAR AND PLANETARY EXPLORATION  (8)
  • Mice
  • Models, Molecular
  • ddc:330
  • 1980-1984  (35)
  • 1
    Electronic Resource
    Electronic Resource
    Direct and correlated responses to selection for weaning weight, post-weaning weight gain and six-week weight in mice (1984)
    Springer
    Theoretical and applied genetics 67 (1984), S. 113-122 
    Details
    ISSN: 1432-2242
    Keywords: Mice ; Selection ; Growth ; Genetic correlation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Four lines of mice were formed from a common base population and selected for 37 generations for either increased 3-week weight (weaning weight), 6-week weight, 3–6 week gain, or maintained as a randomly bred control line. Realised heritability estimates for short-term (long-term) responses were 0.33±0.20 (0.07±0.10), 0.46±0.14 (0.26±0.09), 0.36±0.14 (0.24±0.11) for 3-week weight, 6-week weight and 3–6 week gain, respectively. Realised genetic correlations estimated from short-term (long-term) responses were 0.23±0.08 (0.35±0.10) between 3-week weight and 3–6 week gain; 0.82±0.04 (0.58±0.08) between 3-week weight and 6-week weight; and 0.81±0.04 (0.97±0.04) between 3–6 week gain and 6-week weight. The genetic correlation between 3-week weight and 6-week weight was asymmetric with a greater correlated response for 3-week weight when selecting for 6-week weight (1.06) than vice versa (0.63).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00317015
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    Paper (German National Licenses)
    Fulltext
  • 2
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    Diphenylhydantoin: an alternative ligand of a glucocorticoid receptor affecting prostaglandin generation in A/J mice (1982)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1982-12-24
    Description: Evidence for the binding of 5,5-diphenylhydantoin and glucocorticoids to a common receptor is presented for pulmonary and hepatic cytosols and thymocytes of A/J female mice. The 5,5-diphenylhydantoin-protein complex is absorbed by DNA cellulose, and is incorporated into nuclei, 5,5-Diphenylhydantoin, like glucocorticoids, inhibits the production of prostaglandins in thymocytes. Thus a common receptor is probably responsible for the inhibitory and teratogenic effects of these drugs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Katsumata, M -- Gupta, C -- Baker, M K -- Sussdorf, C E -- Goldman, A S -- DE-4622/DE/NIDCR NIH HHS/ -- DE-5041/DE/NIDCR NIH HHS/ -- DE-5592/DE/NIDCR NIH HHS/ -- New York, N.Y. -- Science. 1982 Dec 24;218(4579):1313-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6897299" target="_blank"〉PubMed〈/a〉
    Keywords: 6-Ketoprostaglandin F1 alpha/biosynthesis ; Animals ; Binding, Competitive ; Cleft Palate/chemically induced ; Dexamethasone/metabolism ; Liver/metabolism ; Lung/metabolism ; Mice ; Phenytoin/*metabolism ; Prostaglandins/*biosynthesis ; Receptors, Glucocorticoid/*metabolism ; Receptors, Steroid/*metabolism ; Thromboxane B2/biosynthesis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    PAPER CURRENT
  • 3
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    A case study of the sensitivity of forecast skill to data and data analysis techniques (1983)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: A series of experiments have been conducted to examine the sensitivity of forecast skill to various data and data analysis techniques for the 0000 GMT case of January 21, 1979. These include the individual components of the FGGE observing system, the temperatures obtained with different satellite retrieval methods, and the method of vertical interpolation between the mandatory pressure analysis levels and the model sigma levels. It is found that NESS TIROS-N infrared retrievals seriously degrade a rawinsonde-only analysis over land, resulting in a poorer forecast over North America. Less degradation in the 72-hr forecast skill at sea level and some improvement at 500 mb is noted, relative to the control with TIROS-N retrievals produced with a physical inversion method which utilizes a 6-hr forecast first guess. NESS VTPR oceanic retrievals lead to an improved forecast over North America when added to the control.
    Keywords: METEOROLOGY AND CLIMATOLOGY
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    NASA TECHNICAL REPORTS
  • 4
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    Channels and valleys on Mars (1983)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: Tentative conclusions about the origins of channels and valleys on Mars based on the consensus of investigators who have studied the problem are presented. The morphology of outflow channels is described in detail, and the morphology, distribution, and genesis of Martian valleys are addressed. Secondary modification of channels and valleys by mass-wasting phenomena, eolian processes, cratering, and mantling by lava flows is discussed. The physics of the flows needed to account for the immense volumes of Martian outflow channels is considered in detail, including the possible influence of debris flows and mudflows, glaciers, and ice sheets. It is concluded that Mars once probably possessed an atmosphere with higher temperatures and pressures than at present which played an essential role in an active hydrological cycle.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Geological Society of America, Bulletin (ISSN 0016-7606); 94; 1035-105
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  • 5
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    An assessment of the FGGE satellite observing system during SOP-1 (1982)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: The sensitivity of a Goddard Laboratory for Atmospheric Sciences global objective analysis cycle to the addition of FGGE level II-b data is assessed. The GOAS system comprises a predictive continuity provided by a model first-guess forecast integrated from a previous forecast and updated by data gathered in the interim. FGGE data originated in the Jan.-Mar. 1979 period and were acquired by rawinsondes, pilot balloons, surface stations, satellites, ships, and drifting buoys deployed during SOP-1. Focussing on 2-5 and 8-day forecasts, comparisons were made of the 6 hr forecast error at the 300 mb height in three experiments using all, no-satellite (NOSAT), and without rawinsondes or pilot balloons modes. Larger errors occurred in the case of NOSAT, while significant corrections to the GOAS predictions were noted using all the FGGE data. It was concluded that all forecasts were improved by inclusion of full FGGE data sets, including forecasting beyond one week.
    Keywords: METEOROLOGY AND CLIMATOLOGY
    Type: American Meteorological Society; vol. 63
    Format: text
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  • 6
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    Numerical prediction of the monsoon depression of 5-7 July 1979 (1981)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: A well defined monsoon depression was used for two assimilation and forecast experiments: (1) using conventional surface and upper air data, (2) using these data plus Monex data. The data sets were assimilated and used with a general circulation model to make numerical predictions. The model, the analysis and assimilation procedure, the differences in the analyses due to different data inputs, and the differences in the numerical predictions are described. The MONEX data have a positive impact, although the differences after 24 hr are not significant. The MONEX assimilation does not agree with manual analysis location of depression center. The 2.5 x 3 deg horizontal resolution of the prediction model is too coarse. The assimilation of geopotential height data derived from satellite soundings generated gravity waves with amplitudes similar to the meteorologically significant features investigated.
    Keywords: METEOROLOGY AND CLIMATOLOGY
    Type: WMO Intern. Conf. on Early Results of FGGE and Large-Scale Aspects of its Monsoon Expt.; 8 p
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    NASA TECHNICAL REPORTS
  • 7
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    The role of zonally asymmetric heating in the vertical and temporal structure of the global scale flow fields during FGGE SOP-1 (1981)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: By examining the vertical structure of the low order spherical harmonics of the divergence and vorticity fields, the relative contribution of tropical and monsoonal circulations upon the global wind fields was estimated. This indicates that the overall flow over North America and the Pacific between January and February is quite distinct both in the lower and upper troposphere. In these longitudes there is a stronger tropical overturning and subtropical jet stream in January than February. The divergent flow reversed between 850 and 200 mb. Poleward rotational flow at upper levels is associated with an equatorward rotational flow at low levels. This suggests that the monsoon and other tropical circulations project more amplitude upon low order (global scale) representations of the flow than do the typical midlatitude circulations and that their structures show conspicuous changes on a time scale of a week or less.
    Keywords: METEOROLOGY AND CLIMATOLOGY
    Type: WMO Intern. Conf. on Early Results of FGGE and Large-Scale Aspects of its Monsoon Expt.; 9 p
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  • 8
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    Numerical prediction of the monsoon depression of 5-7 July, 1979 (1981)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: The objective analysis and assimilation procedure with the FGGE/MONEX data are described. Numerical predictions with the GLAS general circulation model were made from the two initial conditions arrived at by assimilating the two different data sets. The model, the analysis and assimilation procedure, the differences in the analyses due to different data inputs, and the differences in the numerical prediction of monsoon depressions are outlined.
    Keywords: METEOROLOGY AND CLIMATOLOGY
    Type: Modeling and Simulation Facility: Res. Rev., 1980 - 1981; p 223-230
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  • 9
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    The state of the atmosphere as inferred from the FGGE satellite observing systems during SOP-1 (1981)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: The statistical properties, and coverage, of satellite temperature sounding data are described. Tropical regions are observed every two days, extratropics from one to four times a day. Oceans are covered two to three times a day. Asynoptic coverage is comparable to the U.S. rawinsonde network twice daily coverage. Lack of ground truth for data sparse areas makes accuracy difficult to assess. The rms differences of layer mean temperatures obtained from collocating rawinsonde observations with satellite temperature profiles in space and time differ from rms differences of layer mean satellite temperature soundings. The FGGE satellite systems can infer the three dimensional motion field and improve the representation of the large scale state of the atmosphere.
    Keywords: METEOROLOGY AND CLIMATOLOGY
    Type: WMO Intern. Conf on Early Results of FGGE and Large-Scale Aspects of its Monsoon Expt.; 15 p
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    NASA TECHNICAL REPORTS
  • 10
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    FGGE forecast impact studies in the Southern Hemisphere (1983)
    In:  Other Sources
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    Publication Date: 2011-08-18
    Description: The purpose of this paper is to quantify the impact of the FGGE SOS on the GLAS analyses and forecasts in the Southern Hemisphere, and to evaluate the relative importance of its components, and in particular, the impact of the loss of surface buoys. This discussion is limited to the forecast impact of the FGGE system upon a region between 28 deg S and 56 deg S, 50 deg W-80 W which includes essentially the southern cone of South America. Although forecast skill is verified against the NMC analysis, which used only VTPR but no TIROS-N data in the Southern Hemisphere, enough conventional data exists over this region to avoid biased verifications.
    Keywords: METEOROLOGY AND CLIMATOLOGY
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