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  • Chironomus messenger RNA  (1)
  • Electron paramagnetic resonance and relaxation  (1)
  • cimetidine
  • 1980-1984  (3)
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Publisher
Years
  • 1980-1984  (3)
Year
  • 1
    ISSN: 1432-041X
    Keywords: Balbiani ring ; Cell-free translation ; Chironomus messenger RNA ; Secretory proteins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Cell-free translation of salivary gland RNA or of purified Balbiani ring RNA (75S) in a reticulocyte lysate system gives rise to high molecular weight translational products (HMTP). In addition to a common size (approx. 1×106 daltons) HMTP share imunogenic determinants with the giant secretory proteins of salivary glands. This suggests that HMTP correspond to in vivo secreted proteins and thus, corroborates the notion that 75S-RNA is the messenger for these proteins. The time course of HMTP synthesis and the lack of appearance of lower molecular weight components as translational products of 75S-RNA indicate that the synthesis of HMTP (and of secretory proteins) occurs in one piece by an uninterrupted process. HMTP are regarded the largest polypeptides so far synthesized in a cell-free system.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 1964-1970 
    ISSN: 0392-6737
    Keywords: Electron paramagnetic resonance and relaxation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Gli ioni di sostituzione Co2+ e Mn2+ in due diverse posizioni nel Cd nel composto CsCdCl3 sono state studiati usando la risonanza paramagnetica elettronica. L'occupazione preferenziale, Co2+ nel sito CdII, Mn2+ nel sito CdI, è discussa in termini di argomenti di simmetria della chimica dei cristalli.
    Abstract: Резюме Используя электронный парамагнитный резонанс, в соединении CsCdCl3 исследуются местоположения ионов замещения Co2+ и Mn2+ в двух различных положениях Cd. В терминах кристалло-химической симметрии обсуждается предпочтительное расположение Co2+ в положении CdII и Mn2+ в положении CdI.
    Notes: Summary Substitutional Co2+ and Mn2+ ions at the two different Cd sites in the compound CsCdCl3 have been studied by using electron paramagnetic resonance. The preferential occupation, Co2+ in the CdII site, Mn2+ in the CdI site, is discussed in terms of crystallochemical symmetry arguments.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1041
    Keywords: clobazam ; cimetidine ; N-desmethylclobazam ; kinetic interaction ; man
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetic interaction between clobazam and cimetidine was studied in 9 healthy male volunteers in an open-labelled study. After a single oral dose of clobazam 30 mg, a wash-out period of 14 days was followed by daily doses of cimetidine 1 g for one week. Thereafter a single oral dose of clobazam 30 mg was again given. The plasma concentrations of clobazam and its main metabolite N-desmethyl-clobazam were measured by gas-chromatography. The area under the curve (AUC0−∞) of plasma clobazam level was significantly larger after pretreatment with cimetidine and the elimination half life of clobazam was significantly longer. There were no statistically significant differences in Cmax and tmax for plasma clobazam. The plasma levels of N-desmethyl-clobazam did not show any significant change after the intake of cimetidine.
    Type of Medium: Electronic Resource
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