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  • Biochemistry and Biotechnology  (22)
  • Humans  (13)
  • Engineering General  (11)
  • 1980-1984  (46)
  • 1
    Electronic Resource
    Electronic Resource
    Response of a continuous culture of saccharomyces cerevisiae to variation of temperature (1980)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 22 (1980), S. 231-235 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260220118
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  • 2
    Electronic Resource
    Electronic Resource
    A Computer-aided noninterfering on-line technique for monitoring oxygen-transfer characteristics during fermentation processes (1982)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 24 (1982), S. 1605-1621 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The role of computers in the monitoring and control of fermentation processes has increased steadfastly. The ultimate utility of the machines will not depend on the availability of online sensors but also on the availability of techniques that combine direct measurements, leading towards estimates of variable closely related to the microbial process or its control. In this article, a methodology for on-line and noninterfering evaluation of the volumetric mass-transfer coefficient Kla is developed. A detailed presentation of the procedure, called “the static method,” is given. Its feasibility is proved through implementation of the method on an antibiotic fermentation process. These experiments indicate that operator actions meant to modify the oxygen-transfer conditions can be checked on-line. The quantitative value of the static method is ascertained by comparing the experimental results with Kla estimates obtained with the “gassing-out” method. A sensitivity analysis was carried out, revealing the need for temperature and pressure corrections and showing that the precision of the oxygen analyzer determines the precision of the static method.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260240713
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  • 3
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    Ferritin synthesis by human T lymphocytes (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-08-29
    Description: Mononuclear cells from peripheral blood of normal humans, unselected spleen cells from patients with Hodgkin's disease, and selected T and non-T lymphoid cells from normal peripheral blood and from the spleens of Hodgkin's disease patients were examined for de novo synthesis and secretion of ferritin. After precipitation of labeled lysates and supernatants from unseparated and selected T cells with antiserum to human liver ferritin, two bands were visible on sodium dodecyl sulfate-polyacrylimide gel analysis. The two bands were detected in molecular weight regions 19,000 and 21,000, which are thought to represent the L and H subunits of the ferritin molecule, respectively. The slower band (subunit H) was more radioactive than the faster band (subunit L). The H subunit is found in greater amounts in the serum of some tumor patients, but its cellular origin has not been established. The present findings indicate that cells of the immune system contribute to the synthesis and secretion of a ferritin molecule with a high proportion of H subunits.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Dorner, M H -- Silverstone, A -- Nishiya, K -- de Sostoa, A -- Munn, G -- de Sousa, M -- New York, N.Y. -- Science. 1980 Aug 29;209(4460):1019-21.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6967622" target="_blank"〉PubMed〈/a〉
    Keywords: Cell Separation/methods ; Ferritins/*biosynthesis/secretion ; Hodgkin Disease/blood ; Humans ; Macromolecular Substances ; T-Lymphocytes/*metabolism/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    Recognition of HLA-A2 by cytotoxic T lymphocytes after DNA transfer into human and murine cells (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-30
    Description: A gene coding for the major histocompatibility antigen HLA-A2 was transferred into human HLA-A2 negative M1 cells and murine L cells. Following transfection, these cells expressed molecules at the cell surface that are biochemically indistinguishable from HLA-A2 antigens on the human cell line JY from which the HLA-A2 gene was isolated. The M1A2 cells were recognized and lysed by a cytolytic T-cell clone specific for HLA-A2. The transfected L cells which express HLA-A2 in association with human beta 2-microglobulin were not lysed by this T-cell clone. The specific cytolysis of M1A2 cells could be inhibited by monoclonal antibodies to HLA-A2, and monoclonal antibodies to T3, T8, and LFA-1 on cytotoxic T lymphocytes. These results suggest that killing by allospecific T cells requires HLA-A2 antigens as well as other species-specific structures on the target cell surface.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉van de Rijn, M -- Bernabeu, C -- Royer-Pokora, B -- Weiss, J -- Seidman, J G -- de Vries, J -- Spits, H -- Terhorst, C -- AI 19148/AI/NIAID NIH HHS/ -- AI-15066/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 1984 Nov 30;226(4678):1083-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6333726" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; Cytotoxicity, Immunologic ; *Genes ; HLA Antigens/*genetics ; HLA-A2 Antigen ; Humans ; L Cells (Cell Line)/immunology ; *Major Histocompatibility Complex ; Mice ; T-Lymphocytes, Cytotoxic/*immunology ; *Transfection
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
    Electronic Resource
    Electronic Resource
    Some computational aspects of elastic-plastic large strain analysis (1981)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 17 (1981), S. 15-41 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The governing equations for large strain analysis of elastic-plastic problems are reconsidered. An improved form of these equations is derived, which is valid for small increments of strain and large increments of rotation. Special attention is paid to the integration procedures for these equations in the deformation history. It is shown that the tangent modulus procedure for integration of the constitutive equations is conditionally stable, and that implicit methods, such as the ‘mean normal’ method, are to be preferred. A novel procedure is introduced for the treatment of nonlinear geometric effects. The performance of various element types is examined, with specific attention to effects of ‘locking’ and distortion. Several applications are discussed to illustrate the various aspects of the formulation developed ein this paper.
    Additional Material: 24 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620170103
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  • 6
    Electronic Resource
    Electronic Resource
    An ‘upwind’ finite element method via numerical intergration (1982)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 18 (1982), S. 381-396 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Upwind finite element schemes remove spurious oscillations that occur in the solution of diffusion convection equations. Up to now these schemes lose part of their accuracy when the Peclet is large. As an improvement, it is proposed to move the integration nodes along the ‘streamlines’ before evaluating the elementary convection matrices. The displacements of the nodes along the streamlines, which are one-dimensional manifolds, are calculated analogously to well-known one-dimensional formulae. The last section of this paper illustrates this new method with the help of four examples which show its validity.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620180306
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  • 7
    Electronic Resource
    Electronic Resource
    A posteriori error analysis and adaptive processes in the finite element method: Part II - adaptive mesh refinement (1983)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 19 (1983), S. 1621-1656 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: This is a paper presented in two parts dealing respectively with error analysis and adaptive processes applied to finite element calculations. Part I contains the basic theory and methods of deriving error estimates for second-order problems. Part II of the paper deals with the strategy for adaptive refinement and concentrates again on the p-convergent methods. It is shown that an extremely high rate of convergence is reached in practical problems using such procedures. Applications to realistic stress analysis and potential problems are presented.
    Additional Material: 18 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620191104
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  • 8
    Electronic Resource
    Electronic Resource
    A posteriori error analysis and adaptive processes in the finite element method: Part I - error analysis (1983)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 19 (1983), S. 1593-1619 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: This is a paper presented in two parts dealing respectively with error analysis and adaptive processes applied to finite element calculations. Part I contains the basic theory and methods of deriving error estimates for second-order problems. Part II of the paper deals with the strategy for adaptive refinement and concentrates on the p-convergent methods. It is shown that an extremely high rate of convergence is reached in practical problems using such procedures. Applications to realistic stress analysis and potential problems are presented.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620191103
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  • 9
    Electronic Resource
    Electronic Resource
    MAGGY2, a program package for two-dimensional magnestostatic problemsCopyright N.V. Philips' Gloeilampentabrieken, Eindhoven, The Netherlands (Publication No. UDV-DSA/ SCA/SP/78/093/pa). All rights strictly reserved. Reproduction or issue to third parties in any form whatever is not permitted without written authority from the proprietor. (1980)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 15 (1980), S. 113-127 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: This paper describes the essential features of the program package MAGGY2. With MAGGY2, magnetostatic problems in two dimensions can be analysed. The co-ordinate system may be Cartesian, cylindrical or polar. A finite element method with bilinear isoparametric quadrilaterals is used. Input must be given in the problem-oriented language MAGLAN. This language is based on the idea that a user of MAGGY2 wants to describe his problem rather than give commands for its solution. The algorithm and the problem-oriented language are described. Some examples showing the use of the package are given.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620150110
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  • 10
    Electronic Resource
    Electronic Resource
    Plastic straining, unstressing and branching in large displacement perturbation analysis (1984)
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 20 (1984), S. 2077-2092 
    Details
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: The nonlinear system of equations and inequalities relating to the large displacement behaviour of elasto-plastic structures can be transformed by the method of perturbations into an infinite sequence of recursive linear complementarity problems (LCP). Each such LCP can be solved by a simple variant of the simplex algorithm of linear programming. Special consideration is given to describing those steps of the algorithm that are needed for detecting and controlling the phenomena of plastic straining, unstressing and branching.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nme.1620201110
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