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  • ASTRODYNAMICS  (4)
  • 4-hydroxylation  (1)
  • renal failure  (1)
  • 1980-1984  (6)
Collection
Keywords
Publisher
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    Clinical pharmacokinetics and pharmacodynamics of fazadinium in renal failure (1981)
    Springer
    European journal of clinical pharmacology 20 (1981), S. 293-298 
    Details
    ISSN: 1432-1041
    Keywords: neuromuscular relaxants ; fazadinium ; pharmacokinetics ; renal failure ; neuromuscular transmission
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetic behaviour and neuromuscular blockade produced by the administration of fazadinium bromide at a dose of 1 mg/kg have been studied in seven patients with end-stage renal failure. No significant differences were found in the pharmacokinetic or pharmacodynamic properties when compared with patients with normal renal function. It is suggested that fazadinium may be superior to either d-tubocurarine or pancuronium in providing muscle relaxation for patients with renal failure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00618780
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Polymorphic 4-hydroxylation of debrisoquine in chronic discoid psoriasis (1981)
    Springer
    European journal of clinical pharmacology 21 (1981), S. 257-258 
    Details
    ISSN: 1432-1041
    Keywords: debrisoquine ; psoriasis ; chronic discoid psoriasis ; 4-hydroxylation ; microsomal oxidation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary 1. The 4-hydroxylation of debrisoquine was measured in 42 patients with chronic discoid psoriasis. 2. The proportion of poor metabolisers (4.8%) and the median metabolic ratio (0.5) in psoriatics were similar to that reported previously in a healthy British population. 3. We conclude that the abnormality of microsomal mono-oxygenase activity which we have found in the skin and other tissues of psoriatics is not due to a generalised (non-specific) impairment of microsomal oxidation and may be enzyme specific.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00627929
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    Paper (German National Licenses)
    Fulltext
  • 3
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    Unknown
    Precision orbit computations for an operational environment (1981)
    In:  CASI
    Details
    Publication Date: 2016-06-07
    Description: Taking advantage of the improvements to the Earth's gravitation field and tracking station coordinates, an orbital computational consistency of the order of 5 meters was achieved for total position differences between orbital solutions for the Seasat and GEOS-3. The main source of error in these solutions was in the mathematical models that are required to generate these results, i.e., gravitation, atmospheric drag, etc. Different Earth gravitation fields and tracking coordinates were analyzed and evaluated in obtaining these computational results. Comparisons and evaluations of the Seasat results were obtained in terms of different solution types such as the Doppler only, Laser only, Doppler and Laser, etc. Other investigation using the Seasat data were made in order to determine their effect on the computational results at this particular level of consistency.
    Keywords: ASTRODYNAMICS
    Type: Sixth Ann. Flight Mech.(Estimation Theory Symp.; 36 p
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 4
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    Orbit determination and prediction study for Dynamic Explorer 2 (1983)
    In:  CASI
    Details
    Publication Date: 2019-06-28
    Description: Definitive orbit determination accuracy and orbit prediction accuracy for the Dynamic Explorer-2 (DE-2) are studied using the trajectory determination system for the period within six weeks of spacecraft reentry. Baseline accuracies using standard orbit determination models and methods are established. A promising general technique for improving the orbit determination accuracy of high drag orbits, estimation of random drag variations at perigee passages, is investigated. This technique improved the fit to the tracking data by a factor of five and improved the solution overlap consistency by a factor of two during a period in which the spacecraft perigee altitude was below 200 kilometers. The results of the DE-2 orbit predictions showed that improvement in short term prediction accuracy reduces to the problem of predicting future drag scale factors: the smoothness of the solar 10.7 centimeter flux density suggests that this may be feasible.
    Keywords: ASTRODYNAMICS
    Type: NASA-TM-85098 , NAS 1.15:85098
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 5
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    Techniques for increasing the efficiency of Earth gravity calculations for precision orbit determination (1981)
    In:  CASI
    Details
    Publication Date: 2019-06-28
    Description: Two techniques were analyzed. The first is a representation using Chebyshev expansions in three-dimensional cells. The second technique employs a temporary file for storing the components of the nonspherical gravity force. Computer storage requirements and relative CPU time requirements are presented. The Chebyshev gravity representation can provide a significant reduction in CPU time in precision orbit calculations, but at the cost of a large amount of direct-access storage space, which is required for a global model.
    Keywords: ASTRODYNAMICS
    Type: NASA. Goddard Space Flight Center Sixth Ann. Flight Mech.(Estimation Theory Symp.; 28 p
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 6
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    Definitive orbit determination for the HEAO-2 spacecraft (1984)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: Precise ephemerides for the High Energy Astronomy Observatory-2 (HEAO-2) were computed to assist in the Charles Stark Draper Laboratory development of an onboard orbit determination technique. Weighted least-squares, batch orbit solutions were calculated using a high-precision earth gravity model and an approximate model for intermittent spacecraft thrusting. With these improvements, orbit solution consistencies at the 50- to 100-meter level were attained using the Goddard Trajectory Determination System and NASA S-band tracking data.
    Keywords: ASTRODYNAMICS
    Type: AAS PAPER 83-317
    Format: text
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    NASA TECHNICAL REPORTS
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