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  • Chemical Engineering  (54)
  • Analytical Chemistry and Spectroscopy  (10)
  • Animals  (8)
  • 1980-1984  (48)
  • 1970-1974  (24)
  • 1
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    Morphiceptin (NH4-tyr-pro-phe-pro-COHN2): a potent and specific agonist for morphine (mu) receptors (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-04-03
    Description: The synthetic peptide NH2-Tyr-Pro-Phe-Pro-CONH2 (morphiceptin), which is the amide of a fragment of the milk protein beta-casein, has morphinelike activities and is highly specific for morphine (mu) receptors but not for enkephalin (delta) receptors. It is as active as morphine in the guinea pig ileum but much less active in the mouse and rat vas deferens. The discovery of this specific morphine receptor ligand substantiates the hypothesis of multiple opiate receptors. The ligand, which may be of physiological significance since a very similar, or identical, activity can be detected in enzymatic digests of beta-casein, may prove useful for further investigation of the functions of opiate receptor subtypes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Chang, K J -- Lillian, A -- Hazum, E -- Cuatrecasas, P -- Chang, J K -- New York, N.Y. -- Science. 1981 Apr 3;212(4490):75-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6259732" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Binding, Competitive ; Caseins/pharmacology ; Dihydromorphine/metabolism ; Endorphins/*pharmacology ; Enkephalins/metabolism ; Guanosine Triphosphate/pharmacology ; Guinea Pigs ; Ileum/drug effects ; Male ; Mice ; Naloxone/metabolism ; Rats ; Receptors, Opioid/*drug effects ; Sodium/pharmacology ; Vas Deferens/drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Immunoreactive dynorphin-(1-8) and corticotropin- releasing factor in subpopulation of hypothalamic neurons (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-01-14
    Description: Immunoreactive corticotropin-releasing factor (CRF) and dynorphin-(I-8) were visualized in rat hypothalamus by immunohistofluorescence with specific antibodies. In brains from colchicine-treated, adrenalectomized rats, neuronal perikarya with immunoreactive CRF were observed in the paraventricular nucleus of the hypothalamus. The CRF occurred together with the dynorphin-(1-8). However, the CRF immunoreactivity occurred only in a subpopulation of the dynorphin-(1-8) immunoreactive cells. These findings suggest that there may be a functional interrelationship of CRF with dynorphin-related opioid peptides and provide further evidence that neurons may contain more than one bioactive substance.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Roth, K A -- Weber, E -- Barchas, J D -- Chang, D -- Chang, J K -- New York, N.Y. -- Science. 1983 Jan 14;219(4581):189-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6129700" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Corticotropin-Releasing Hormone/immunology/*metabolism ; Dynorphins ; Endorphins/immunology/*metabolism ; Fluorescent Antibody Technique ; Hypothalamus/cytology/*metabolism ; Neurons/metabolism ; Paraventricular Hypothalamic Nucleus/metabolism ; Peptide Fragments/metabolism ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
    Electronic Resource
    Electronic Resource
    Reversed-phase high-performance thin-layer chromatography of mono-, di- and trisubstituted bile acid methyl esters (1983)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 6 (1983), S. 617-620 
    Details
    ISSN: 0935-6304
    Keywords: High-performance thin-layer chromatography, HPTLC ; Reversed-phase ; Octadecyl-bonded silica gel ; Bile acid methyl esters ; Methyl 5β -cholanates ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A comparative study is reported on separation of series of mono-, di-, and trisubstituted methyl 5β-cholanates, which differ only in the position and stereochemistry of hydroxyl or keto groups at position and stereochemistry of hydroxyl or keto groups at positions C-3, C-7, and/or C-12, by reversed-phase [with chemically-bonded (C-18) silica gel] and normal-phase (silica gel) high-performance thin-layer chromatography (HPTLC). Methnol (or acetonitrile)/water systems were employed as mobile phase. Reversed-phase HPTLC found to be particulary effective for separation of the stereoisomers of di- and trisubstituted compounds whereas the less polar monosubstituted isomers are well resolved in normal-phase HPTLC.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240061106
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  • 4
    Electronic Resource
    Electronic Resource
    A criterion for fully developed flow of polymer melts in a circular tube (1970)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 16 (1970), S. 499-501 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690160334
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  • 5
    Electronic Resource
    Electronic Resource
    Letter to the Editor (1971)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 17 (1971), S. 258-510 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690170205
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  • 6
    Electronic Resource
    Electronic Resource
    Convective dispersion of blood gases in curved channel exchangers (1971)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 17 (1971), S. 541-549 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The rates of hemoglobin saturation and carbon dioxide reduction in blood flowing in a curved channel membrane exchanger were studied theoretically by considering the fluid-limited process and the wall-limited process. The fluid-limited process was studied for laminar flows with and without secondary circulations. The relatively nontraumatic centrifugally induced circulations in the curved channel can reduce the required channel length to less than 1/500 that required for unperturbed flow. Such improvement, however, is practical only if very permeable membranes are available. If the PO2 = 715 mm. Hg and PCO2 = 0 mm. Hg at the walls, the fluid-limited analyses show oxygenation to be the slower process and the wall-limited analyses indicate CO2 removal to be the limiting process. If the best available silicone rubber membranes are used, the process will be fluid limited for the unperturbed flow and wall limited for the flow with secondary circulations.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690170312
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  • 7
    Electronic Resource
    Electronic Resource
    Eqation of state for phase equilibrium: I. Pure component (1971)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 17 (1971), S. 596-602 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: An equation of state for the two-phase region whose constants depend only on the critical pressure, the critical temperature, the normal boiling temperature, and the latent heat at the normal boiling point is shown to describe vapor pressure, latent heat, and saturation volumes of methane well.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690170322
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  • 8
    Electronic Resource
    Electronic Resource
    Thermal conductivity of a nonequilibrium chemically reacting gas (1971)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 17 (1971), S. 1304-1310 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Thermal conductivity measurements were made for the dissociating system 2 NO2 ⇋ 2NO + O2. Experiments were made at temperatures from 548° to 792°K. and pressures from 1 to 30 atm. Under these conditions the chemical reaction is in a nonequilibrium state, and the rate of energy transport is limited by the rates of the forward and reverse reactions. Experimental results agreed very well with a theoretical model based on a linearized reaction rate expression. Using the thermal conductivity results, it was also possible to determine the chemical kinetic constants for the reaction.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690170608
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  • 9
    Electronic Resource
    Electronic Resource
    Die swell behavior of two-phase polymer melts (1971)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 17 (1971), S. 1512-1514 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690170643
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  • 10
    Electronic Resource
    Electronic Resource
    On intrinsic errors in pressure-hole measurements in flow of polymer melts (1972)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 18 (1972), S. 116-121 
    Details
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: In order to investigate the possibilities of pressure-hole errors in the measurement of wall normal stresses in the flow of polymer melts, a 2.280-in. long slit die has been designed, having a slot with a rectangular cross section, 0.050 in. by 1.000 in. Three transducers were mounted on each of the two long sides of the rectangular slot along the longitudinal center line of the die and located so that each transducer was directly opposite another in the opposite side. The three transducers on one side were flush mounted. Those on the other side were mounted through pressure-holes with different diameters (0.017, 0.034, and 0.050 in.) Measurements of wall normal stresse were made with high density polyethylene and polypropylene melts at 200°C., following the experimental procedure described in the author's earlier papers. The present study indicates that pressure measurements made through pressureholes are essentially the same as those made flush-mounted instruments, and that there are no pressure hole errors in the measurements of wall normal stresses, insofar as polymer melts are concerned.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aic.690180121
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