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  • Springer  (87)
  • American Physical Society (APS)
  • 1985-1989  (65)
  • 1970-1974  (22)
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Year
  • 11
    Electronic Resource
    Electronic Resource
    Purines and cortisone in lipid mobilization (1970)
    Springer
    Cellular and molecular life sciences 26 (1970), S. 128-129 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Purin-Basen, Kaffein und Cortison führen zu einer Vermehrung der Fettsäuren im Rattenserum. Adenin vermindert im Gegensatz zu den anderen Purinen die Lipolyse.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01895532
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  • 12
    Electronic Resource
    Electronic Resource
    Degradation of haemoglobin-14C and urinary excretion of bilirubin-14C by the normothermic perfused isolated dog kidney (1973)
    Springer
    Cellular and molecular life sciences 29 (1973), S. 410-411 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé L'hémoglobine libre du sang, filtrée par les glomérules rénaux et partiellement absorbée par les tubules, est métabolisée par le tissu renal. A l'aide de l'hémoglobine marquée en14C, formée à partir de la glycine-2-14C et de la glycine-1-14C nos résultats prouvent que chez le chien mâle les reins métabolisent l'hémoglobine en bilirubine conjugée et excrètent cette dernière dans les urines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01926750
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  • 13
    Electronic Resource
    Electronic Resource
    Seasonal allocation of dry mass and nitrogen in a fynbos endemic Restionaceae species Thamnochortus punctatus Pill. (1987)
    Springer
    Oecologia 72 (1987), S. 315-320 
    Details
    ISSN: 1432-1939
    Keywords: Allocation patterns ; Restionaceae ; Nitrogen ; Dry mass ; Fynbos
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The annual growth pattern of male plants of the endemic, dioecious fynbos species, Thamnochortus punctatus, revealed sequential growth of the various below-and above-ground organs. Root and rhizome development were favoured in the wet winter months while culm elongation occurred in the warmer but drier spring to summer period. The reproductive phase of development followed in the hot dry summer and autumn. The asynchronous pattern of growth is suggested to enable the plant to maximize utilization of scarce resources within the confines of the environmental controls determined by the mediterranean-climate. Maximum root and rhizome activity in the rainy season enabled the plant to absorb and store nitrogen in mature culms for later above ground organ development. As the absorption of nitrogen from senscing material is essential for this pattern of organ development to assist in alleviating nutrient scarcity the high degree of nitrogen reabsorption, 35 to 70% for branches and culms respectively, shows the potential importance of asynchronous organ growth in overcoming nitrogen limitation of plant growth. Comparisons of dry mass and nitrogen allocation patterns indicate that developmental strategies employed by evergreen, perennial plants in climatically and edaphically constrained environments cannot be deduced from biomass allocation patterns alone as they do not appear to reflect strategies evolved to overcome nutrient limitation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00379284
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  • 14
    Electronic Resource
    Electronic Resource
    The costs of leaving home: ants disperse myrmecochorous seeds to low nutrient sites (1989)
    Springer
    Oecologia 81 (1989), S. 412-417 
    Details
    ISSN: 1432-1939
    Keywords: Myrmecochory ; Fynbos ; Regeneration ; Fire ; Nutrient
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Leucospermum conocarpodendron (L.) Buek (Proteaceae) seedlings were excavated several months after a fire in Cape fynbos. Seedlings under burnt parental skeletons had short hypocotyls (mean 25 mm) indicating passive dispersal whereas seedlings in the open were more deeply buried (mean 48 mm) by ants. Soil nutrient concentrations at the site of germination were negatively related to depth of burial and distance from parent. Ant dispersal resulted in seedlings emerging in soils with lower nutrient concentrations than passively dispersed seeds. Tissue analysis supported the soil results with lower P content in seedlings from open (ant dispersed) sites. Seedling survival in the first year of establishment was also lower in open sites, but not significantly so. However seedlings were slightly taller in the open. The results of this study, the first on naturally occurring intraspecific variation in myrmecochory, strongly contradict current explanations for the high incidence of myrmecochory in nutrient poor environments.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00377092
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  • 15
    Electronic Resource
    Electronic Resource
    Evolutionary conservatism in arrangement of genetic material (1973)
    Springer
    Chromosoma 43 (1973), S. 211-224 
    Details
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The diploid number of the Rhesus macaque, Macaca mulatta, is 42. All chromosomes are biarmed and all constitutive heterochromatins are centromeric. The diploid number of the African Green monkey, Cercopithecus aethiops, is 60. Again all chromosomes are biarmed, but seven pairs possess very short second arms which are heterochromatic. The heterochromatins of remaining chromosomes are centromeric. Using G-banding and deleting the heterochromatic short arms, the chromosomes of the African Green monkey can be artificially fused to reconstruct a karyotype of the Rhesus with only one pair of unmatched small metacentrics. In addition to the Robertsonian type of translocations, several sets of centromere-telomere translocations were found. The latter type of translocation reduced three arms into two. Thus the fundamental number can be changed by two mechanisms: growing extra heterochromatic arms and the centromere-telomere fusions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00483380
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  • 16
    Electronic Resource
    Electronic Resource
    A method for the isolation of nuclei from the dermatophytic fungus,Microsporum gypseum (1974)
    Springer
    Archives of microbiology 96 (1974), S. 281-289 
    Details
    ISSN: 1432-072X
    Keywords: Fungal Nuclei ; Isolation ; Purification ; Characterization ; Dermatophyte ; Microsporum gypseum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A method is reported for the isolation of nuclei from the dermatophytic fungus,Microsporum gypseum. The yield ranged from greater than 90% in crude preparations to less than 20% in highly purified preparations as judged by the recovery of DNA. Nuclei isolated in this manner appeared intact in electron microscopic observations and possessed chemical compositions, i.e. low protein/DNA and RNA/DNA ratios, which indicated a low degree of cytoplasmic contamination.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00590184
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  • 17
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of 6-thiouric acid and 6-mercaptopurine in renal allograft recipients after oral administration of azathioprine (1989)
    Springer
    European journal of clinical pharmacology 36 (1989), S. 265-271 
    Details
    ISSN: 1432-1041
    Keywords: azathioprine ; 6-thiouric acid ; 6-mercaptopurine ; renal transplantation ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The immunosuppressive activity of azathioprine (AZA) is unpredictable and depends on the formation of intracellular thiopurine ribonucleotides. However, the quantification of these active thiopurines presents difficult analytical problems. It has recently been postulated that plasma concentrations of 6-thiouric acid (6-TU) and 6-mercaptopurine (6-MP), metabolites of AZA, may provide more readily measurable indices of the pharmacologic activity of AZA. In order to evaluate the utility of 6-TU and 6-MP plasma concentrations in monitoring AZA therapy, we studied their pharmacokinetics in 6 renal transplant patients, and their in vitro immunosuppressive potency in a mixed lymphocyte proliferation assay. A peak plasma 6-TU concentration of 710.7 ng/ml was observed at 3.8 h after oral dosing. Good correlation was observed between the elimination t1/2 of 6-TU and serum creatinine, and between AUC over 24 h and serum creatinine. However, we did not observe a second peak in plasma 6-TU concentration that could be attributed to the degradation of active AZA metabolites. 6-MP plasma concentrations in the patients were low (mean peak concentration 36.0 ng/ml) and rapidly disappeared within 8 h. In vitro immunosuppressive activity could not be demonstrated for 6-TU over a concentration range of 1.25 ng/ml to 0.25 mg/ml. We conclude that 6-TU is pharmacologically inert and is primarily eliminated by the kidneys. Our findings currently do not support the use of plasma concentrations of 6-TU or 6-MP to monitor AZA therapy. In order to optimize AZA therapy, analytical techniques that are technically feasible and that can directly quantify the active intracellular thiopurines are being explored.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00558158
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  • 18
    Electronic Resource
    Electronic Resource
    A comparative study of respirable particulate microenvironmental concentrations and personal exposures (1988)
    Springer
    Environmental monitoring and assessment 10 (1988), S. 105-122 
    Details
    ISSN: 1573-2959
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract Personal monitoring (PM) for respirable suspended particulate matter (RSP) of thirty subjects was performed as part of an air pollution health effects study conducted in Houston, Texas. Parallel RSP measurements were performed in the study subjects' homes and two fixed site monitoring stations. The participants' daytime activities were independently recorded by study techicians. These data were used to characterize RSP concentrations in each microenvironment visited by the participants. Four estimates of daytime exposure to RSP were calculated based on two different microenvironmental models, and home and fixed site mean daytime RSP concentrations. These estimates were compared to mean daytime personal exposure from PM. Hourly estimates of exposure were calculated from a microenvironmental model and mean hourly home RSP concentrations and compared to hourly PM data. The results of the study indicate that, as in the case of NO2, it is important to characterize indoor microenvironmental RSP concentrations according to location, sources, and concurrent activities, both qualitatively and quantitatively. Stratification of concentrations according to sources present and self-reported activity can lead to misclassification of exposures. For RSP and, probably, other pollutants with indoor sources and with short exposure integration times, adequate measures of exposure can only be obtained with very detailed and complex microenvironmental models or comprehensive personal monitoring.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00401776
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  • 19
    Electronic Resource
    Electronic Resource
    Whither brown fat? (1986)
    Springer
    Bioscience reports 6 (1986), S. 3-18 
    Details
    ISSN: 1573-4935
    Keywords: brown adipose tissue ; thermogenesis ; cold ; diet ; neural control ; hormonal control
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01145174
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  • 20
    Electronic Resource
    Electronic Resource
    Effect of a selectiveβ 2-adrenergic agonist (Cenbuterol) on energy balance and body composition in normal and protein deficient rats (1987)
    Springer
    Bioscience reports 7 (1987), S. 933-940 
    Details
    ISSN: 1573-4935
    Keywords: body composition ; protein deficiency ; adrenergic agonists
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract In rats fed a normal (22% protein) diet, injection of clenbuterol (1 mg/kg/d for 21 d) did not affect energy intake, energy expenditure or weight gain, but reduced energetic efficiency, and fat and energy gains and increased body protein content. Presenting a low-protein (8%) diet reduced energy intake, gain and efficiency, body protein content and the mass of the gastrocnemius muscle when compared to rats fed the control diet. Injection of the protein-deficient rats with clenbuterol (1 mg/kg/d for 21 d) caused hypophagia and reduced body weight and energy gains, energy expenditure and total body fat. However, the total body content of protein was not significantly reduced and the percentage of body protein in this protein deficient, clenbuterol-treated group was greater than that of untreated rats on both the high- and low-protein diets. The ratio of body protein to fat following clenbuterol treatment was increased by over 50% in both normal and protein-deficient rats. The results show that in protein deficient animals, clenbuterol treatment may help conserve body protein at the expense of fat, resulting in a smaller, but leaner body mass.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01122126
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