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  • GEOPHYSICS  (12)
  • Animals  (4)
  • COMPUTER PROGRAMMING AND SOFTWARE  (4)
  • Spacecraft Design, Testing and Performance
  • ddc:330
  • 1990-1994  (20)
  • 1
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    Hantavirus pulmonary syndrome: an emerging infectious disease (1993)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1993-11-05
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hughes, J M -- Peters, C J -- Cohen, M L -- Mahy, B W -- New York, N.Y. -- Science. 1993 Nov 5;262(5135):850-1.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉National Center for Infectious Diseases, U.S. Department of Health and Human Services, Atlanta, GA 30333.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8235607" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bunyaviridae Infections/*epidemiology/microbiology/therapy ; *Disease Outbreaks ; Disease Reservoirs ; Hantavirus/*isolation & purification ; Humans ; Lung Diseases/*epidemiology/microbiology/therapy ; Peromyscus/*microbiology ; Pulmonary Edema ; Southwestern United States/epidemiology ; United States/epidemiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis (1994)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1994-07-29
    Description: Rasmussen's encephalitis is a progressive childhood disease of unknown cause characterized by severe epilepsy, hemiplegia, dementia, and inflammation of the brain. During efforts to raise antibodies to recombinant glutamate receptors (GluRs), behaviors typical of seizures and histopathologic features mimicking Rasmussen's encephalitis were found in two rabbits immunized with GluR3 protein. A correlation was found between the presence of Rasmussen's encephalitis and serum antibodies to GluR3 detected by protein immunoblot analysis and by immunoreactivity to transfected cells expressing GluR3. Repeated plasma exchanges in one seriously ill child transiently reduced serum titers of GluR3 antibodies, decreased seizure frequency, and improved neurologic function. Thus, GluR3 is an autoantigen in Rasmussen's encephalitis, and an autoimmune process may underlie this disease.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rogers, S W -- Andrews, P I -- Gahring, L C -- Whisenand, T -- Cauley, K -- Crain, B -- Hughes, T E -- Heinemann, S F -- McNamara, J O -- NS17771/NS/NINDS NIH HHS/ -- NS28709/NS/NINDS NIH HHS/ -- NS30990R29/NS/NINDS NIH HHS/ -- etc. -- New York, N.Y. -- Science. 1994 Jul 29;265(5172):648-51.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Salt Lake City Geriatric Research Education and Clinical Center, Veterans Affairs Medical Center, UT.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8036512" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antibody Specificity ; Autoantibodies/blood/*immunology ; Brain/pathology ; Cell Line ; Child ; Disease Models, Animal ; Encephalitis/complications/*immunology/pathology/therapy ; Female ; Humans ; Male ; Plasma Exchange ; Rabbits ; Receptors, Glutamate/*immunology ; Recombinant Fusion Proteins/immunology ; Seizures/etiology/immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Fatty acylation of two internal lysine residues required for the toxic activity of Escherichia coli hemolysin (1994)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1994-12-23
    Description: Hemolysin of Escherichia coli is activated by fatty acylation of the protoxin, directed by the putative acyl transferase HlyC and by acyl carrier protein (ACP). Mass spectrometry and Edman degradation of proteolytic products from mature toxin activated in vitro with tritium-labeled acylACP revealed two fatty-acylated internal lysine residues, lysine 564 and lysine 690. Resistance of the acylation to chemical treatments suggested that fatty acid was amide linked. Substitution of the two lysines confirmed that they were the only sites of acylation and showed that although each was acylated in the absence of the other, both sites were required for in vivo toxin activity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stanley, P -- Packman, L C -- Koronakis, V -- Hughes, C -- New York, N.Y. -- Science. 1994 Dec 23;266(5193):1992-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pathology, Cambridge University, UK.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7801126" target="_blank"〉PubMed〈/a〉
    Keywords: Acyl Carrier Protein/metabolism ; Acylation ; Acyltransferases/metabolism ; Amino Acid Sequence ; Animals ; Bacterial Proteins/chemistry/metabolism/*toxicity ; Bacterial Toxins/chemistry/metabolism/*toxicity ; *Escherichia coli ; *Escherichia coli Proteins ; Hemolysin Proteins/chemistry/metabolism/*toxicity ; Hemolysis ; Horses ; Lysine/metabolism ; Mass Spectrometry ; Molecular Sequence Data ; Protein Precursors/metabolism ; Sequence Alignment
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 4
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    An experimental study of inbreeding depression in a natural habitat (1994)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1994-10-14
    Description: Inbreeding is known to lead to decreased survival and reproduction in captive populations of animals. It is also important to know whether inbreeding has deleterious effects in natural habitats. An estimate was made of the effects of inbreeding in white-footed mice, Peromyscus leucopus noveboracensis, derived from a wild population. This study demonstrates that inbreeding had a significant detrimental effect on the survivorship of mice reintroduced into a natural habitat. This effect was more severe than the effect observed in laboratory studies of the population.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jimenez, J A -- Hughes, K A -- Alaks, G -- Graham, L -- Lacy, R C -- New York, N.Y. -- Science. 1994 Oct 14;266(5183):271-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Sciences, University of Illinois-Chicago 60680.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7939661" target="_blank"〉PubMed〈/a〉
    Keywords: Analysis of Variance ; Animals ; Body Weight ; Female ; *Inbreeding ; Likelihood Functions ; Male ; Peromyscus/genetics/*physiology ; Regression Analysis ; Survival Rate
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 5
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    Dayside ionospheric convection changes in response to long-period interplanetary magnetic field oscillations - Determination of the ionospheric phase velocity (1992)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: Ground magnetic field perturbations recorded by the CANOPUS magnetometer network in the 7 to 13 MLT sector are used to examine how reconfigurations of the dayside polar ionospheric flow take place in response to north-south changes of the IMF. During the 6-h interval in question, IMF Bz oscillates between +/- 7 nT with about a 1-h period. Corresponding variations in the ground magnetic disturbance are observed which we infer are due to changes in ionospheric flow. Cross correlation of the data obtained from two ground stations at 73.5 deg magnetic latitude, but separated by about 2 hours in MLT, shows that changes in the flow are initiated in the prenoon sector (about 10 MLT) and then spread outward toward dawn and dusk with a phase speed of about 5 km/s over the longitude range about 8 to 12 MLT, slowing to about 2 km/s outside this range. Cross correlating the data from these ground stations with IMP 8 IMF Bz records produces a MLT variation in the ground response delay relative to the IMF which is compatible with these deduced phase speeds.
    Keywords: GEOPHYSICS
    Type: Journal of Geophysical Research (ISSN 0148-0227); 97; A12; p. 19,373-19,380.
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  • 6
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    The Generic Spacecraft Analyst Assistant (gensaa): a Tool for Developing Graphical Expert Systems (1993)
    In:  CASI
    Details
    Publication Date: 2014-08-29
    Description: During numerous contacts with a satellite each day, spacecraft analysts must closely monitor real-time data. The analysts must watch for combinations of telemetry parameter values, trends, and other indications that may signify a problem or failure. As the satellites become more complex and the number of data items increases, this task is becoming increasingly difficult for humans to perform at acceptable performance levels. At NASA GSFC, fault-isolation expert systems are in operation supporting this data monitoring task. Based on the lessons learned during these initial efforts in expert system automation, a new domain-specific expert system development tool named the Generic Spacecraft Analyst Assistant (GenSAA) is being developed to facilitate the rapid development and reuse of real-time expert systems to serve as fault-isolation assistants for spacecraft analysts. Although initially domain-specific in nature, this powerful tool will readily support the development of highly graphical expert systems for data monitoring purposes throughout the space and commercial industry.
    Keywords: COMPUTER PROGRAMMING AND SOFTWARE
    Type: NASA, Washington, Technology 2002: The Third National Technology Transfer Conference and Exposition, Volume 1; p 268-278
    Format: application/pdf
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  • 7
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    CLEAR: Automating control centers with expert system technology (1990)
    In:  CASI
    Details
    Publication Date: 2013-08-31
    Description: The Communications Link Expert Assistance Resource (CLEAR) is a fault-isolation expert system to be utilized in the operational environment of the Cosmic Background Explorer (COBE) Mission Operations Room (MOR). CLEAR will assist the COBE Flight Operations Team (FOT) during periods of real-time data acquisition by isolating faults in the spacecraft communication link with the Tracking and Data Relay Satellite (TDRS), providing advice on how to correct them, and logging the events for post-pass evaluation. After a brief introduction to the problem domain, the system requirements, tool selection, development approach, system operation and lessons learned during the transformation of the system from the prototype to the delivered, operation system are described.
    Keywords: COMPUTER PROGRAMMING AND SOFTWARE
    Type: NASA, Lyndon B. Johnson Space Center, Third Annual Workshop on Space Operations Automation and Robotics (SOAR 1989); p 289-293
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  • 8
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    CD volume design and verification (1993)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: In this paper, we describe a prototype for CD-ROM volume design and verification. This prototype allows users to create their own model of CD volumes by modifying a prototypical model. Rule-based verification of the test volumes can then be performed later on against the volume definition. This working prototype has proven the concept of model-driven rule-based design and verification for large quantity of data. The model defined for the CD-ROM volumes becomes a data model as well as an executable specification.
    Keywords: COMPUTER PROGRAMMING AND SOFTWARE
    Type: AIAA PAPER 93-4709 , In: AIAA Computing in Aerospace Conference, 9th, San Diego, CA, Oct. 19-21, 1993, Technical Papers. Pt. 2 (A94-11401 01-62); p. 1366-1369.
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  • 9
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    Observations of Earthward and tailward propagating flux rope plasmoids: Expanding the plasmoid model of geomagnetic substorms (1994)
    In:  Other Sources
    Details
    Publication Date: 2019-07-13
    Description: A survey of Interplanetary Monitoring Platform (IMP 8) magnetometer data for plasmoid signatures during magnetospheric intervals from 1981 through 1983 found 16 plasmoids and 37 traveling compression regions as well as two earthward propagating flux ropes and 19 south-north bipolar lobe signatures. The properties of these relatively near-Earth plasmoids, traveling compression regions, and earthward propagating flux ropes and a qualitative model for their formation are presented. The plasmoids have estimated sizes, durations, magnetic field signatures, downtail velocities, and substorm associations very similar to those of the plasmoids identified in International Sun-Earth Explorer (ISEE) 3 deep-tail observations. The occurrence frequency of these near-Earth plasma sheet plasmoids is significantly smaller than that of plasmoids found in the mid- and deep tail with ISEE 3. The earthward propagating flux ropes are characterized by a south-north bipolar turning in the Geocentric Solar Magnetospheric (GSM) B(sub z) component, are localized near the noon-midnight meridional plane, and are strongly correlated with interplanetary magnetic field B(sub z) north and small isolated high latitude geomagnetic substorms. These events are also apparently very rare and/or spatially localized. We propose that these structures are 'proto-plasmoids,' i.e., plasmoids for which near-Earth magnetic reconnection stopped before all the closed plasma sheet field lines were reconnected. The proto-plasmoids are then 'trapped' inside closed magnetic field lines and propagate earthward owing to the effect of the distant X-line's earthward plasma flow. We suggest that the two different 'types' of plasmoids are due to the different energy states of the magnetosphere during periods of southward and northward interplanetary magnetic field.
    Keywords: GEOPHYSICS
    Type: Journal of Geophysical Research (ISSN 0148-0227); 99; A1; p. 183-198
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  • 10
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    Analysis of a virtual memory model for maintaining database views (1992)
    In:  Other Sources
    Details
    Publication Date: 2019-07-12
    Description: This paper presents an analytical model for predicting the performance of a new support strategy for database views. This strategy, called the virtual method, is compared with traditional methods for supporting views. The analytical model's predictions of improved performance by the virtual method are then validated by comparing these results with those achieved in an experimental implementation.
    Keywords: COMPUTER PROGRAMMING AND SOFTWARE
    Type: IEEE Transactions on Software Engineering (ISSN 0098-5589); 18; 5 Ma; 402-409
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