ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • GEOPHYSICS  (32)
  • AERODYNAMICS  (15)
  • Female
  • 1990-1994  (19)
  • 1985-1989  (16)
  • 1980-1984  (16)
  • 1
    facet.materialart.
    Unknown
    Digenic retinitis pigmentosa due to mutations at the unlinked peripherin/RDS and ROM1 loci (1994)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1994-06-10
    Description: In spite of recent advances in identifying genes causing monogenic human disease, very little is known about the genes involved in polygenic disease. Three families were identified with mutations in the unlinked photoreceptor-specific genes ROM1 and peripherin/RDS, in which only double heterozygotes develop retinitis pigmentosa (RP). These findings indicate that the allelic and nonallelic heterogeneity known to be a feature of monogenic RP is complicated further by interactions between unlinked mutations causing digenic RP. Recognition of the inheritance pattern exemplified by these three families might facilitate the identification of other examples of digenic inheritance in human disease.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kajiwara, K -- Berson, E L -- Dryja, T P -- EY00169/EY/NEI NIH HHS/ -- EY08683/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1994 Jun 10;264(5165):1604-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Berman-Gund Laboratory for the Study of Retinal Degenerations, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston 02114.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8202715" target="_blank"〉PubMed〈/a〉
    Keywords: Alleles ; Amino Acid Sequence ; Base Sequence ; Electroretinography ; Eye Proteins/chemistry/*genetics ; Female ; Genes, Dominant ; Genes, Recessive ; Genetic Linkage ; Heterozygote ; Humans ; Intermediate Filament Proteins/chemistry/*genetics ; Male ; *Membrane Glycoproteins ; Membrane Proteins/chemistry/*genetics ; Molecular Sequence Data ; Mutation ; *Nerve Tissue Proteins ; Pedigree ; Peripherins ; Retinitis Pigmentosa/*genetics ; Rod Cell Outer Segment/chemistry ; Tetraspanins
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 2
    facet.materialart.
    Unknown
    The conserved pre-mRNA splicing factor U2AF from Drosophila: requirement for viability (1993)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1993-10-22
    Description: The large subunit of the human pre-messenger RNA splicing factor U2 small nuclear ribonucleoprotein auxiliary factor (hU2AF65) is required for spliceosome assembly in vitro. A complementary DNA clone encoding the large subunit of Drosophila U2AF (dU2AF50) has been isolated. The dU2AF50 protein is closely related to its mammalian counterpart and contains three carboxyl-terminal ribonucleoprotein consensus sequence RNA binding domains and an amino-terminal arginine- and serine-rich (R/S) domain. Recombinant dU2AF50 protein complements mammalian splicing extracts depleted of U2AF activity. Germline transformation of Drosophila with the dU2AF50 complementary DNA rescues a lethal mutation, establishing that the dU2AF50 gene is essential for viability. R/S domains have been found in numerous metazoan splicing factors, but their function is unknown. The mutation in Drosophila U2AF will allow in vivo analysis of a conserved R/S domain-containing general splicing factor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kanaar, R -- Roche, S E -- Beall, E L -- Green, M R -- Rio, D C -- R01-HD28063/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1993 Oct 22;262(5133):569-73.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular and Cell Biology, University of California, Berkeley 94720.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7692602" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Base Sequence ; Conserved Sequence ; DNA, Complementary ; Drosophila melanogaster/*genetics/growth & development ; Female ; Gene Transfer Techniques ; Genes, Insect ; Genes, Lethal ; In Situ Hybridization ; Male ; Molecular Sequence Data ; Mutation ; *Nuclear Proteins ; RNA/metabolism ; RNA Precursors/*metabolism ; *RNA Splicing ; Recombinant Proteins/metabolism ; Ribonucleoproteins/chemistry/*genetics/metabolism ; Sequence Alignment
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Exposure of rats to alcohol in utero alters drug sensitivity in adulthood (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-06-26
    Description: Pregnant rats were intubated with alcohol (ethanol, 3 grams per kilogram) twice daily throughout gestation. Control animals received solutions of isocaloric sucrose. At birth, offspring were placed with untreated surrogate dams. Beginning at 6 months of age, the offspring were tested for their thermogenic responsiveness to various drugs and to cold. Prenatal exposure to alcohol resulted in tolerance to alcohol and cross-tolerance to pentobarbital and diazepam but did not affect responsiveness to cold. This pattern of effects suggest that prenatal exposure to alcohol produces specific long-term effects on the neural mechanisms underlying drug tolerance.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Abel, E L -- Bush, R -- Dintcheff, B A -- New York, N.Y. -- Science. 1981 Jun 26;212(4502):1531-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7233243" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chlorpromazine/pharmacology ; Dextroamphetamine/pharmacology ; Diazepam/pharmacology ; Drug Hypersensitivity ; Drug Tolerance ; Ethanol/*pharmacology ; Female ; Fetus/*drug effects ; Morphine/pharmacology ; Pentobarbital/pharmacology ; Pregnancy ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 4
    facet.materialart.
    Unknown
    Artificial sweetener use and bladder cancer: a case-control study (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-03-14
    Description: In a case-control study of 302 male and 65 female bladder cancer patients and an equal number of other patients matched to them in age, sex, hospital, and hospital-room status, no association was found between use of artificial sweeteners or diet beverages and bladder cancer. No dose-response was observed with respect to quantity or duration of use of the two combined. No evidence was found to suggest that artificial sweeteners or diet beverages promote the tumorigenic effect of tobacco smoking. Artificial sweetener and diet beverage use strongly reflected socioeconomic status among controls with various diagnoses.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wynder, E L -- Stellman, S D -- New York, N.Y. -- Science. 1980 Mar 14;207(4436):1214-6.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7355283" target="_blank"〉PubMed〈/a〉
    Keywords: Female ; Humans ; Male ; Sex Factors ; Smoking/*complications ; Sweetening Agents/*adverse effects ; Urinary Bladder Neoplasms/chemically induced/*etiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 5
    facet.materialart.
    Unknown
    In situ measurements of the NO2/NO ratio for testing atmospheric photochemical models (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: Simultaneous in situ measurements of NO2, NO, O3, ClO, pressure and temperature have been made for the first time, presenting a unique opportunity to test our current understanding of the photochemistry of the lower stratospere. Data were collected from several flights of the ER-2 aircraft at mid-latitudes in May 1993 during NASA's Stratospheric Photochemistry, Aerosols and Dynamics Expedition (SPADE). The daytime ratio of NO2/NO remains fairly constant at 19 km with a typical value of 0.68 and standard deviation of +/- 17. The ratio observations are compared with simple steady-state calculations based on laboratory-measured reaction rates and modeled NO2 photolysis rates. At each measurement point the daytime NO2/NO with its measurements uncertainty overlap the results of steady-state caculations and associated uncertainty. Possible sources of error are examined in both model and measurements. It is shown that more accurate laboratory determinations of the NO + 03 reaction rate and of the NO2 cross-sections in the 200-220 K temperature range characteristic of the lower stratosphere would allow for a more robust test of our knowledge of NO(X) phtochemistry by reducing significant sources if uncertainties in the interpretation of statospheric measurements.
    Keywords: GEOPHYSICS
    Type: Geophysical Research Letters (ISSN 0094-8276); 21; 23; p. 2555-2558
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 6
    facet.materialart.
    Unknown
    Excitation of the low lying vibrational levels of H2O by O(3P) as measured on Spacelab 2 (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: The data from the infrared telescope (IRT), which was flown on space shuttle Challenger Spacelab 2 mission (July 1985), were originally reported by Koch et al. (1987) as originating from near orbital emissions, primarily H2O. In this study, analysis of this data was extended to determine the collisional cross sections for the excitation of the low lying vibrational levels of H2O, present in the orbiter cloud, by atmospheric O(3P). The evaluation of the contribution to the measured signal from solar excitation and ram O excitation of outgassing H2O permits the determination of the H2O column density and the excitation cross section of the (101) level at an O(3P) velocity of approximately 7.75 km/s. Contributions to the radiation in the 1.7-3.0 micron band by transitions from the (100), (001), and multiquantum excited levels are discussed. The findings of the study are (1) the IRT data for the 4.5-9.5 micron and the nighttime data for the 1.7-3.0 micron sensors are consistent with being explained by collision excitation of H2O by O(3P), (2) diurnal variations of 4.5-9.5 micron intensities follow the model predicted O density for a full orbit, (3) daytime increases in the H2O cloud density were not evident, (4) the cross sections for the collisional excitation process are derived and compared to values computated by Johnson (1986) and Redmon et al. (1986), (5) theoretical investigation suggests greater than 60% of the radiation from H2O is a result of multiphoton emission resulting from collisional multiquanta excitation, and (6) the large daytime increase in the 1.7-3.0 micron intensity data suggests that O(+) may likely be instrumental in producing excited H2O(+) through charge exchange.
    Keywords: GEOPHYSICS
    Type: Journal of Geophysical Research (ISSN 0148-0227); 99; A9; p. 17,559-17,575
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 7
    facet.materialart.
    Unknown
    Are models of catalytic removal of O3 by HO(x) accurate? Constraints from in situ measurements of the OH to HO2 ratio (1994)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: Measurements of the ratio OH/HO2, NO, O3, ClO, and BrO were obtained at altitudes from 15-20 km and latitudes from 15-60 deg N. A method is presented for interpreting the rates of chemical transformations that (1) are responsible for over half the ozone removal rate in the lower stratosphere via reactions of HO2; and (2) control the abundance of HO2 through coupling to nitrogen and halogen radicals. The results show our understanding of the chemical reactions controlling the partitioning of OH and HO2 is complete and accurate and that the potential effects of 'missing chemistry' are strickly constrained in the region of the atmosphere encompassed by the observations. The analysis demonstrates that the sensitivity of the ratio OH/HO2 to changes in NO is described to within 12% by current models. This reduces by more than a factor of 2 the effect of uncertainty in the coupling of hydrogen and nitrogen radicals on the analysis of the potential effects of perturbations to odd notrogen in the lower statosphere.
    Keywords: GEOPHYSICS
    Type: Geophysical Research Letters (ISSN 0094-8276); 21; 23; p. 2539-2542
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 8
    facet.materialart.
    Unknown
    ISEE 3 plasmoid and TCR observations during an extended interval of substorm activity (1992)
    In:  Other Sources
    Details
    Publication Date: 2011-08-24
    Description: On April 9-11, 1983, the ISEE 3 spacecraft was continuously located within the earth's magnetotail for more than 36 hours at downstream distances of X = -76 to -80 R(e). During this span of time, 12 major intervals of substorm activity were observed in the AL index with good ISEE 3 telemetry coverage for 11 of them. In addition, there were two small substorms outside of these intervals, both with complete observations in the distant tail. This unusual ISEE 3 data set provides a unique opportunity to test the predictions of the near-earth neutral line model. In particular, the hypothesis that energy stored in the tail lobes during the growth phase is later dissipated, in part, through the release of one or more plasmoids following expansion phase onset is examined. Clear growth phase enhancements in the lobe magnetic field intensity preceded the onsets of nine of the substorms. Plasmoids, or their lobe signatures, traveling compression regions (TCRs), were observed at ISEE 3 in association with all 11 of the major substorm intervals for which there were ISEE observations, as well as for the two small substorms. No plasmoids or TCRs were observed in the absence of substorm activity. If these ISEE 3 observations are representative, then the release of plasmoids down the tail may be a feature common to all substorms.
    Keywords: GEOPHYSICS
    Type: Geophysical Research Letters (ISSN 0094-8276); 19; 8, Ap
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 9
    facet.materialart.
    Unknown
    A tidal wind model for 85-120 km based on CIRA-86 - A feasibility study (1991)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: The feasibility of deriving a climatology of the diurnal variations of the wind in the 85-120 km region from the tidal components of density, temperature and composition contained in the new COSPAR CIRA-86 is examined. The CIRA density and temperature model is employed to derive the eastward and northward pressure gradient forces that serve as the forcing functions in the coupled momentum equations. At midlatitudes, the model shows some of the general features observed in the radar tidal data, e.g., the dominant semidiurnal tide with increasing amplitude with height and clockwise (counterclockwise) rotation of the velocity vector seen in the Northern (Southern) Hemisphere.
    Keywords: GEOPHYSICS
    Type: Journal of Atmospheric and Terrestrial Physics (ISSN 0021-9169); 53; 425-445
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
  • 10
    facet.materialart.
    Unknown
    Algebraic grid generation about wing-fuselage bodies (1987)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: An algebraic procedure for generating boundary-fitted grids about wing-fuselage configurations is presented. A wing-fuselage configuration consists of two aircraft components specified by cross sections and mathematically represented by Coons' patches. Several grid blocks are constructed to cover the entire region surrounding the configuration, and each grid block maps into a computational cube. Grid points are first determined on the six boundary surfaces of a block and then in the interior. Grid points on the surface of the configuration are derived from the intersection of planes with the Coons' patch definition. Approximate arc length distributions along the resulting grid curves concentrate and disperse grid points. The two-boundary technique and transfinite interpolation are used to determine grid points on the remaining boundary surfaces and block interiors.
    Keywords: AERODYNAMICS
    Type: Journal of Aircraft (ISSN 0021-8669); 24; 868-872
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    NASA TECHNICAL REPORTS
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...