ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Mutation  (6)
  • 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk  (4)
  • 2005-2009  (7)
  • 2000-2004  (3)
  • 1
    Electronic Resource
    Electronic Resource
    A novel HLA-A*6816 allele possibly generated by a point mutation in a Chilean from Punta Arenas (Magellan Strait) (2000)
    Springer
    Immunogenetics 51 (2000), S. 257-260 
    Details
    ISSN: 1432-1211
    Keywords: Key words Amerindians ; Chileans ; HLA-A*6816 ; Mutation ; Gene conversion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002510050618
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    facet.materialart.
    Unknown
    Strigolactone inhibition of shoot branching (2008)
    Nature Publishing Group (NPG)
    Details
    Publication Date: 2008-08-12
    Description: A carotenoid-derived hormonal signal that inhibits shoot branching in plants has long escaped identification. Strigolactones are compounds thought to be derived from carotenoids and are known to trigger the germination of parasitic plant seeds and stimulate symbiotic fungi. Here we present evidence that carotenoid cleavage dioxygenase 8 shoot branching mutants of pea are strigolactone deficient and that strigolactone application restores the wild-type branching phenotype to ccd8 mutants. Moreover, we show that other branching mutants previously characterized as lacking a response to the branching inhibition signal also lack strigolactone response, and are not deficient in strigolactones. These responses are conserved in Arabidopsis. In agreement with the expected properties of the hormonal signal, exogenous strigolactone can be transported in shoots and act at low concentrations. We suggest that endogenous strigolactones or related compounds inhibit shoot branching in plants. Furthermore, ccd8 mutants demonstrate the diverse effects of strigolactones in shoot branching, mycorrhizal symbiosis and parasitic weed interaction.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gomez-Roldan, Victoria -- Fermas, Soraya -- Brewer, Philip B -- Puech-Pages, Virginie -- Dun, Elizabeth A -- Pillot, Jean-Paul -- Letisse, Fabien -- Matusova, Radoslava -- Danoun, Saida -- Portais, Jean-Charles -- Bouwmeester, Harro -- Becard, Guillaume -- Beveridge, Christine A -- Rameau, Catherine -- Rochange, Soizic F -- England -- Nature. 2008 Sep 11;455(7210):189-94. doi: 10.1038/nature07271.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Universite de Toulouse, UPS, CNRS, Surface Cellulaire et Signalisation chez les Vegetaux, 24 chemin de Borde Rouge, F-31326 Castanet-Tolosan, France.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18690209" target="_blank"〉PubMed〈/a〉
    Keywords: Arabidopsis/drug effects/genetics/growth & development ; Arabidopsis Proteins/genetics/metabolism ; Dioxygenases ; Genes, Plant/genetics ; Lactones/analysis/chemistry/*metabolism/pharmacology ; Mutation ; Mycorrhizae/physiology ; Oxygenases/genetics/metabolism ; Peas/drug effects/growth & development/*metabolism/parasitology ; Phenotype ; Plant Growth Regulators/analysis/chemistry/*metabolism/pharmacology ; Plant Proteins/genetics/metabolism ; Plant Roots/drug effects/metabolism ; Plant Shoots/drug effects/*growth & development/*metabolism/parasitology ; Symbiosis ; Terpenes/analysis/chemistry/metabolism/pharmacology
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Published by Nature Publishing Group (NPG)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 3
    facet.materialart.
    Unknown
    Engineering modified Bt toxins to counter insect resistance (2007)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2007-11-03
    Description: The evolution of insect resistance threatens the effectiveness of Bacillus thuringiensis (Bt) toxins that are widely used in sprays and transgenic crops. Resistance to Bt toxins in some insects is linked with mutations that disrupt a toxin-binding cadherin protein. We show that susceptibility to the Bt toxin Cry1Ab was reduced by cadherin gene silencing with RNA interference in Manduca sexta, confirming cadherin's role in Bt toxicity. Native Cry1A toxins required cadherin to form oligomers, but modified Cry1A toxins lacking one alpha-helix did not. The modified toxins killed cadherin-silenced M. sexta and Bt-resistant Pectinophora gossypiella that had cadherin deletion mutations. Our findings suggest that cadherin promotes Bt toxicity by facilitating toxin oligomerization and demonstrate that the modified Bt toxins may be useful against pests resistant to standard Bt toxins.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Soberon, Mario -- Pardo-Lopez, Liliana -- Lopez, Idalia -- Gomez, Isabel -- Tabashnik, Bruce E -- Bravo, Alejandra -- 1R01 AI066014/AI/NIAID NIH HHS/ -- New York, N.Y. -- Science. 2007 Dec 7;318(5856):1640-2. Epub 2007 Nov 1.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Apartado Postal 510-3, Cuernavaca 62250, Morelos, Mexico. mario@ibt.unam.mx〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17975031" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Bacterial Proteins/chemistry/*genetics/metabolism/*toxicity ; Bacterial Toxins/chemistry/*genetics/metabolism/*toxicity ; Cadherins/genetics/metabolism ; Endotoxins/chemistry/*genetics/metabolism/*toxicity ; Genetic Engineering ; Hemolysin Proteins/chemistry/*genetics/metabolism/*toxicity ; *Insecticide Resistance ; Larva ; *Manduca/genetics/metabolism ; *Moths/genetics/metabolism ; Mutation ; *Pest Control, Biological ; RNA Interference
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 4
    facet.materialart.
    Unknown
    Protection of C. elegans from anoxia by HYL-2 ceramide synthase (2009)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2009-04-18
    Description: Oxygen deprivation is rapidly deleterious for most organisms. However, Caenorhabditis elegans has developed the ability to survive anoxia for at least 48 hours. Mutations in the DAF-2/DAF-16 insulin-like signaling pathway promote such survival. We describe a pathway involving the HYL-2 ceramide synthase that acts independently of DAF-2. Loss of the ceramide synthase gene hyl-2 results in increased sensitivity of C. elegans to anoxia. C. elegans has two ceramide synthases, hyl-1 and hyl-2, that participate in ceramide biogenesis and affect its ability to survive anoxic conditions. In contrast to hyl-2(lf) mutants, hyl-1(lf) mutants are more resistant to anoxia than normal animals. HYL-1 and HYL-2 have complementary specificities for fatty acyl chains. These data indicate that specific ceramides produced by HYL-2 confer resistance to anoxia.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Menuz, Vincent -- Howell, Kate S -- Gentina, Sebastien -- Epstein, Sharon -- Riezman, Isabelle -- Fornallaz-Mulhauser, Monique -- Hengartner, Michael O -- Gomez, Marie -- Riezman, Howard -- Martinou, Jean-Claude -- New York, N.Y. -- Science. 2009 Apr 17;324(5925):381-4. doi: 10.1126/science.1168532.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Cell Biology, University of Geneva, CH-1211 Geneva 4, Switzerland.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19372430" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Apoptosis ; Caenorhabditis elegans/cytology/genetics/*physiology ; Caenorhabditis elegans Proteins/*genetics/*metabolism ; *Cell Hypoxia ; Ceramides/biosynthesis/*physiology ; Gene Deletion ; Genes, Helminth ; Mutation ; Oxidoreductases/*genetics/*metabolism ; Oxygen/*physiology ; Receptor, Insulin/genetics/metabolism ; Saccharomyces cerevisiae/genetics/growth & development/physiology ; Sphingomyelins/biosynthesis/physiology ; Substrate Specificity ; Transformation, Genetic ; Transgenes
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 5
    facet.materialart.
    Unknown
    Selective trafficking of non-cell-autonomous proteins mediated by NtNCAPP1 (2003)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2003-01-18
    Description: In plants, cell-to-cell communication is mediated by plasmodesmata and involves the trafficking of non-cell-autonomous proteins (NCAPs). A component in this pathway, Nicotiana tabacum NON-CELL-AUTONOMOUS PATHWAY PROTEIN1 (NtNCAPP1), was affinity purified and cloned. Protein overlay assays and in vivo studies showed that NtNCAPP1 is located on the endoplasmic reticulum at the cell periphery and displays specificity in its interaction with NCAPs. Deletion of the NtNCAPP1 amino-terminal transmembrane domain produced a dominant-negative mutant that blocked the trafficking of specific NCAPs. Transgenic tobacco plants expressing this mutant form of NtNCAPP1 and plants in which the NtNCAPP1 gene was silenced were compromised in their ability to regulate leaf and floral development. These results support a model in which NCAP delivery to plasmodesmata is both selective and regulated.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lee, Jung-Youn -- Yoo, Byung-Chun -- Rojas, Maria R -- Gomez-Ospina, Natalia -- Staehelin, L Andrew -- Lucas, William J -- GM18639/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 2003 Jan 17;299(5605):392-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Section of Plant Biology, Division of Biological Sciences, University of California, 1 Shields Avenue, Davis, CA 95616, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12532017" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Cell Communication ; Cell Line ; Cloning, Molecular ; Cytoplasm/metabolism ; Endoplasmic Reticulum/metabolism ; Flowers/growth & development ; Gene Silencing ; Green Fluorescent Proteins ; Immunohistochemistry ; Luminescent Proteins/metabolism ; Molecular Sequence Data ; Mutation ; Phenotype ; Plant Leaves/growth & development ; Plant Proteins/chemistry/genetics/*isolation & purification/*metabolism ; Plants, Genetically Modified ; Plasmodesmata/*metabolism ; Protein Transport ; Recombinant Fusion Proteins/metabolism ; Tobacco/genetics/growth & development/*metabolism ; Tobacco Mosaic Virus ; Viral Proteins/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 6
    facet.materialart.
    Unknown
    Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques (2004)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 2004-07-13
    Description: We describe the efficacy of L-870812, an inhibitor of HIV-1 and SIV integrase, in rhesus macaques infected with the simian-human immunodeficiency virus (SHIV) 89.6P. When initiated before CD4 cell depletion, L-870812 therapy mediated a sustained suppression of viremia, preserving CD4 levels and permitting the induction of virus-specific cellular immunity. L-870812 was also active in chronic infection; however, the magnitude and durability of the effect varied in conjunction with the pretreatment immune response and viral load. These studies demonstrate integrase inhibitor activity in vivo and suggest that cellular immunity facilitates chemotherapeutic efficacy in retroviral infections.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hazuda, Daria J -- Young, Steven D -- Guare, James P -- Anthony, Neville J -- Gomez, Robert P -- Wai, John S -- Vacca, Joseph P -- Handt, Larry -- Motzel, Sherri L -- Klein, Hilton J -- Dornadula, Geethanjali -- Danovich, Robert M -- Witmer, Marc V -- Wilson, Keith A A -- Tussey, Lynda -- Schleif, William A -- Gabryelski, Lori S -- Jin, Lixia -- Miller, Michael D -- Casimiro, Danilo R -- Emini, Emilio A -- Shiver, John W -- New York, N.Y. -- Science. 2004 Jul 23;305(5683):528-32. Epub 2004 Jul 8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Chemistry, Merck Research Laboratories, Post Office Box 4, West Point, PA 19486, USA. daria_hazuda@merck.com〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15247437" target="_blank"〉PubMed〈/a〉
    Keywords: Acquired Immunodeficiency Syndrome/*drug therapy/*immunology/virology ; Animals ; Anti-HIV Agents/administration & dosage/blood/pharmacology/therapeutic use ; CD4 Lymphocyte Count ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Cells, Cultured ; Drug Resistance, Viral ; HIV Integrase/genetics/metabolism ; HIV Integrase Inhibitors/administration & dosage/blood/pharmacology/therapeutic ; use ; HIV-1/drug effects/enzymology/genetics/*physiology ; Immunity, Cellular ; Integrase Inhibitors/administration & dosage/blood/pharmacology/*therapeutic use ; Integrases/genetics/metabolism ; Leukocytes, Mononuclear/virology ; Macaca mulatta ; Mutation ; Naphthyridines/administration & dosage/blood/pharmacology/*therapeutic use ; Simian Acquired Immunodeficiency Syndrome/*drug therapy/*immunology/virology ; Simian Immunodeficiency Virus/drug effects/enzymology/genetics/*physiology ; Viral Load ; Viremia/drug therapy ; Virus Replication/drug effects
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
  • 7
    facet.materialart.
    Unknown
    Seismic hazard data for the new, Italian building code based on European standard (2007)
    Details
    Publication Date: 2017-04-04
    Description: Prior to 2003 the Italian building code, established in 1974, was mostly based on working stress design. The zonation that guided its application was made up in 1981 using a semi-quantitative, mainly seismological approach; it was enforced in 1984 and left about 2/3 of the territory without seismic provisions. In 1998 a new zonation was proposed but never adopted. The 2002 Mw5.7 earthquake in Molise (Southern Italy) caused the collapse of a school and the death of 26 children. The school was built in an area where seismic provisions were not applied, although the zonation proposed in 1998 assigned it to the second zone. The earthquake triggered a process that led in a few months to a new set of seismic provisions
    Description: Unpublished
    Description: San Francisco
    Description: open
    Keywords: Seismic hazard data ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: Poster session
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 8
    facet.materialart.
    Unknown
    Mappe di pericolosità sismica in termini di intensità macrosismica utilizzando lo stesso impianto metodologico di MPS04. Progetto INGV-DPC S1, Deliverable D7. (2007)
    Details
    Publication Date: 2017-04-04
    Description: A seismic hazard map, with 10% probability of exceedance in 50 years in terms of macroseismic intensity, is proposed for the Italian territory. The input elements used to evaluate the seismic hazard are: the seismogenic zoning ZS9, the earthquake catalogue CPTI04, the historical and statistical completeness. These elements are those used in MPS04 (Gruppo di Lavoro MPS, 2004). Two new intensity attenuation models were used: 1) a set of regional relationships derived from a previous cubic model (Berardi et al., 1993) which has been recalibrated (Gómez Capera, 2006); 2) a relationship obtained with a new approach (Pasolini et al., 2006). The intensity attenuation models were obtained using the macroseismic intensity database, which was used for compiling CPTI04. The computer code adopted to evaluate the seismic hazard, with the elements cited above, is SeisRisk III, which has been modified to be used with macroseismic intensity data, i.e. allowing to consider the normal distribution of the residuals. A logic tree approach has been used to explore some possible alternatives of epistemic character.
    Description: Istituto Nazionale di Geofisica e Vulcanologia
    Description: Published
    Description: 4.2. TTC - Scenari e mappe di pericolosità sismica
    Description: open
    Keywords: seismic hazard ; macroseismic data ; intensity attenuation ; Italy ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: report
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 9
    facet.materialart.
    Unknown
    Aggiornamento relazioni fra l'intensità macrosismica e PGA. Progetto INGV-DPC S1, Deliverable D11. (2007)
    Details
    Publication Date: 2017-04-04
    Description: Empirical relationships between macroseismic intensity and PGA are useful for comparing the macroseismic observations to recorded peak ground motions and for comparing seismic hazard assessment in terms of intensity with those in PGA. In literature is observed that despite the intensity correlate fairly well with PGA, the relationships I-PGA is the only mathematical instrumental to convert seismic hazard assessment in terms of intensity to PGA. Not many studies deal with the relationship between intensity and PGA and the majority have been published for the western USA and Japan. In Italy, relationships between the intensity data and PGA records have been proposed among others by Margottini et al. (1987, 1992) and by Faccioli and Cauzzi (2006), which used data from earthquakes of the Mediterranean area (Italy, Turkey, Algeria, France and Slovenia). In the present study a probabilistic I-PGA relationship is proposed, based on the datasets from Margottini et. al and from Faccioli and Cauzzi, and adopting a generalized orthogonal regression.
    Description: Istituto Nazionale di Geofisica e Vulcanologia
    Description: Published
    Description: 4.2. TTC - Scenari e mappe di pericolosità sismica
    Description: open
    Keywords: relationships I-PGA ; intensity-PGA ; seismic hazard ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: report
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
  • 10
    facet.materialart.
    Unknown
    Seismic hazard map for the Italian territory using macroseismic data (2007)
    Details
    Publication Date: 2017-04-04
    Description: A seismic hazard map, in terms of macroseismic intensity, is proposed for the Italian continental territory and Sicily, which has a 10% probability of exceedance in 50 years. The methodology used here was first proposed by Cornell (1968), which requires information about the location and seismicity rates within each of the defined seismogenic zones, as well as an attenuation model. In particular, it is proposed an original macroseismic intensity attenuation model derived from the Italian macroseismic database DBMI04. The seismic hazard map, obtained in terms of intensity, was subsequently transformed into PGA by means of a linear relation between intensity and PGA, in order to compare it with the national seismic hazard map MPS04.
    Description: Published
    Description: 67-90
    Description: open
    Keywords: Probabilistic seismic hazard, ; macroseismic data, ; seismogenic zonation, ; intensity attenuation, ; Italy ; 04. Solid Earth::04.06. Seismology::04.06.11. Seismic risk
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER (OA)
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...