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  • Springer  (22)
  • 2010-2014  (1)
  • 1995-1999  (9)
  • 1980-1984  (4)
  • 1945-1949  (4)
  • 1910-1914  (2)
  • 1900-1904  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 29 (1982), S. 416-421 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' journal of analytical chemistry 360 (1998), S. 679-682 
    ISSN: 1432-1130
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract N-Nitroso-triazine herbicide species were synthesized as reference standards and their reaction products were separated by TLC. The method was established for analytical as well as for preparative amounts to achieve a sufficient separation between the educts, the byproducts and the N-nitrosated moieties. Separation of the reaction mixture was performed by two-dimensional TLC, using different mobile phases for each dimension. In the second dimension two developments were executed using the same solvent mixture. To examine the quality of performance, the separation zones were scrapped off, extracted and analyzed in the HPLC-diode array detection (DAD) mode in comparison with standards of the educts and the products of their N-nitrosation. This method minimizes the contact with the resulting N-nitroso compounds. At present nothing is known about the toxicological relevance or risk assessment on human health of N-nitrosocyanazine or N-nitrosoterbuthylazine species. Therefore the practical handling of these putative mutagenic and carcinogenic substances should be seen under the aspect of precaution and prevention of contamination.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 17 (1980), S. 197-202 
    ISSN: 1432-1041
    Keywords: hexobarbital ; cholestasis ; phenobarbital ; rifampicin ; phenytonin ; pharmackoinetics ; drug metabolism ; induction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of intravenously infused hexobarbital was studied in 10 patients with intrahepatic cholestasis and in 9 with extrahepatic biliary obstruction. The results were compared with those obtained in 16 healthy young volunteers and 5 older patients with normal liver function. After infusion, the plasma concentrations showed a rapid initial decline (α-phase) and subsequently a slower decrease (β-phase). The half-life of a latter phase was 323±84 min in the healthy group, 357±151 min in the patients with intrahepatic cholestasis and 344±115 min in the group with biliary obstruction; the clearances were 3.41±0.90, 4.08±1.95 and 3.81±1.97 ml×min−1×kg−1, respectively. The differences were not statistically significant. The mean volume of the central compartment of distribution and the steady state volume of distribution were not significantly different. In two patients hexobarbital clearance during cholestasis was greater than after it had subsided. After treatment of 11 patients with cholestasis with drug metabolism-inducing agents (phenobarbital, rifampicin or phenytoin), the half-life of hexobarbital was significantly shortened and the mean value of hexobarbital clearance was more than doubled.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 8 (1997), S. 301-306 
    ISSN: 1573-482X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract SnO2 gas-sensor films were modified by implantation of gold and iron ions. The change in electrical resistivity of the films caused by inflammable gases, H2, CO, CH4 and C2H5OH, was measured in the temperature range 100–500°C, and compared to non-implanted films. The morphological changes caused by gold and iron ion implantation were also investigated by atomic force microscopy. After ion implantation and annealing at 600°C, the sensitivity to H2 and CO gas was found to increase, and the dynamic range of the sensitivity to ethanol was improved. The sensitivity to CH4 was low before and after ion implantation. Fe2O3 (3%SnO2) film was also modified by gold ion implantation for comparison.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Anchorage-dependent cells (mouse fibroblasts L929 and 3T3) were cultivated on microstructures made by semiconductor technology. Both cell lines showed normal growth on silicon surfaces covered with microelectrode arrays as well as on microperforated silicon membranes with square pores made by anisotropic etching (5, 10 or 20 μm edge length at the top and 1.2, 6.2 or 16.2 μm at the bottom). The cells spread over the 5 and 10 μm pores, but mostly failed to cover the 20 μm ones. They were able to cross the silicon membrane through the pores and to grow and spread on the under side of the membrane. Small pores (about 1 μm2) impeded but did not prevent cells crossing the membrane. Medium and large pores were freely crossed. Negative dielectrophoresis was used to achieve accurate positioning of cells above pores or to repel them from the chip surface (a.c., square wave, 2.5 V peak-to-peak, 5 MHz). The results are discussed with respect to their microtool applications for single-cell technologies.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Monatshefte für Chemie 80 (1949), S. 510-516 
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Monatshefte für Chemie 80 (1949), S. 749-758 
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Zusammenfassung 1. Die untersuchten Chlorex-n-Alkoholsysteme zeigen hohe endotherme Mischungswärmen, die sich mit steigender Temperatur noch vergrößern. 2. Bei den niederen Alkoholsystemen treten Volumkontraktionen, bei den höheren Volumdilatationen auf. 3. Das System Chlorex-Methanol ist in flüssiger Phase unbeschränkt mischbar; sämtliche anderen Alkoholsysteme besitzen Mischungslücken. Die KLT-Werte steigen mit wachsendem Molgewicht des Alkohols an, und zwar ab C3H7OH ziemlich regelmäßig oszillierend. 4. Mit steigendem Molgewicht der Alkohole verschieben sich die ΔH max-Werte in das Alkohol-reichere, dagegen die ΔV max- und KLT-Werte ins Chlorex-reichere Gebiet. Die Systemreihen n-Alkohole-Benzol und n-Alkohole-n-Hexan weisen ganz ähnliche Anomalien auf, die offenbar in der Assoziation und dem mit der Temperatur veränderlichen Assoziationsgrad der Alkoholkomponente begründet sind. 5. Chlorex stellt für die niederen n-Alkohole ein selektives Lösungsmittel dar, währendAnilin mit denselben Alkoholen (bis C8H17OH) in flüssiger Phase unbeschränkt mischbar ist.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Monatshefte für Chemie 80 (1949), S. 856-863 
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Monatshefte für Chemie 80 (1949), S. 572-582 
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Zusammenfassung 1. Die Mischungswärmen der SystemeChlorex—n-Oktan undChlorex—i-Oktan (2,2,4-Trimethylpentan) sind bei 25°C sehr starkendotherm (495, bzw. 440 cal/Mol Mischung bei XChl=0,300) und besitzen einennegativen Temperaturkoeffizienten. 2. Das SystemChlorex—n-Oktan zeigt bei 20°C — das heißt bei eben noch vollständiger gegenseitiger Löslichkeit — eine kleine Volums-dilatation, die sich mit steigender Temperatur (35°) vorerst nur wenig ändert, dann aber (50°) deutlich ausgeprägt ist. Das SystemChlorex—i-Oktan weist bei 20°C — also noch sehr nahe der KLT — eine geringfügige Volumskontraktion auf, die bei 35° noch ebenso gering ist, dann aber (50°) bemerkenswert groß wird. 3. Das Dipolmoment desChlorex-Einzelmoleküls errechnet sich bei 20°C zu 2,47 (Debye) in n-Oktan und 2,60 (Debye) in i-Oktan. 4. Die Zustandsdiagramme beider Systeme sind sehr ähnlich und zeigen tiefe, fast über den gesamten Konzentrationsbereich laufende Zonen beschränkter Mischbarkeit. Die KLT desChlorex—n-Oktan-systems liegt bei+19,7°C, die des i-Oktansystems bei+18,2°C. Für die Schmelzwärme vonChlorex finden wir als Mittelwert 2070 cal/Mol.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Hyperfine interactions 112 (1998), S. 165-168 
    ISSN: 1572-9540
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Iron and magnesium are insoluble elements with each other and there is no phase diagram. However, it is possible to produce artificial alloys by ion implantation, in this study by iron implantation into magnesium. Samples are investigated by conversion electron Moessbauer spectroscopy, Auger electron spectroscopy and x-ray diffraction. While at low doses gaussian shaped iron profiles and paramagnetic doublets as Mössbauer spectra are obtained, the iron concentration reaches at the highest dose 90 at.-% in maximum and the Mössbauer spectrum shows a dominant ferromagnetic fraction. The x-ray diffraction pattern let conclude that a dilated α-iron lattice is formed. Microhardness of all samples is clearly increased due to the implantation.
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