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  • Animals  (3)
  • GEOPHYSICS
  • Spacecraft Design, Testing and Performance
  • ddc:330
  • 2010-2014  (4)
  • 2010  (4)
  • 1
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    Nature Publishing Group (NPG)
    Publication Date: 2010-07-16
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hughes, Virginia -- England -- Nature. 2010 Jul 15;466(7304):S11-3. doi: 10.1038/nature09240.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20631696" target="_blank"〉PubMed〈/a〉
    Keywords: Acquired Immunodeficiency Syndrome/complications/*drug therapy/*virology ; Animals ; Anti-HIV Agents/administration & dosage/adverse effects/pharmacology/therapeutic ; use ; CCR5 Receptor Antagonists ; Disease Reservoirs/virology ; Drug Combinations ; Drug Therapy, Combination ; HIV/*drug effects/enzymology/*isolation & purification ; HIV Infections/complications/*drug therapy/*virology ; HIV Integrase Inhibitors/pharmacology/therapeutic use ; Humans ; Immunologic Memory/drug effects/immunology ; Inflammation/complications/immunology/pathology ; Lymphocyte Activation/drug effects/immunology ; Medication Adherence ; Receptors, CCR5/metabolism ; Survival Analysis ; Treatment Outcome ; Viral Load/*drug effects ; Virus Activation/drug effects/physiology ; Virus Latency/drug effects/physiology ; vif Gene Products, Human Immunodeficiency Virus/antagonists & ; inhibitors/metabolism
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2010-01-15
    Description: The human Y chromosome began to evolve from an autosome hundreds of millions of years ago, acquiring a sex-determining function and undergoing a series of inversions that suppressed crossing over with the X chromosome. Little is known about the recent evolution of the Y chromosome because only the human Y chromosome has been fully sequenced. Prevailing theories hold that Y chromosomes evolve by gene loss, the pace of which slows over time, eventually leading to a paucity of genes, and stasis. These theories have been buttressed by partial sequence data from newly emergent plant and animal Y chromosomes, but they have not been tested in older, highly evolved Y chromosomes such as that of humans. Here we finished sequencing of the male-specific region of the Y chromosome (MSY) in our closest living relative, the chimpanzee, achieving levels of accuracy and completion previously reached for the human MSY. By comparing the MSYs of the two species we show that they differ radically in sequence structure and gene content, indicating rapid evolution during the past 6 million years. The chimpanzee MSY contains twice as many massive palindromes as the human MSY, yet it has lost large fractions of the MSY protein-coding genes and gene families present in the last common ancestor. We suggest that the extraordinary divergence of the chimpanzee and human MSYs was driven by four synergistic factors: the prominent role of the MSY in sperm production, 'genetic hitchhiking' effects in the absence of meiotic crossing over, frequent ectopic recombination within the MSY, and species differences in mating behaviour. Although genetic decay may be the principal dynamic in the evolution of newly emergent Y chromosomes, wholesale renovation is the paramount theme in the continuing evolution of chimpanzee, human and perhaps other older MSYs.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653425/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉   〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653425/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hughes, Jennifer F -- Skaletsky, Helen -- Pyntikova, Tatyana -- Graves, Tina A -- van Daalen, Saskia K M -- Minx, Patrick J -- Fulton, Robert S -- McGrath, Sean D -- Locke, Devin P -- Friedman, Cynthia -- Trask, Barbara J -- Mardis, Elaine R -- Warren, Wesley C -- Repping, Sjoerd -- Rozen, Steve -- Wilson, Richard K -- Page, David C -- R01 HG000257/HG/NHGRI NIH HHS/ -- Howard Hughes Medical Institute/ -- England -- Nature. 2010 Jan 28;463(7280):536-9. doi: 10.1038/nature08700. Epub 2010 Jan 13.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20072128" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Chromosomes, Human, Pair 21/genetics ; Chromosomes, Human, Y/*genetics ; DNA/chemistry/genetics ; Genes/*genetics ; Humans ; Male ; Molecular Sequence Data ; *Nucleic Acid Conformation ; Pan troglodytes/*genetics ; Sequence Homology, Nucleic Acid ; Y Chromosome/*genetics
    Print ISSN: 0028-0836
    Electronic ISSN: 1476-4687
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2010-10-28
    Description: Using data for 25,780 species categorized on the International Union for Conservation of Nature Red List, we present an assessment of the status of the world's vertebrates. One-fifth of species are classified as Threatened, and we show that this figure is increasing: On average, 52 species of mammals, birds, and amphibians move one category closer to extinction each year. However, this overall pattern conceals the impact of conservation successes, and we show that the rate of deterioration would have been at least one-fifth again as much in the absence of these. Nonetheless, current conservation efforts remain insufficient to offset the main drivers of biodiversity loss in these groups: agricultural expansion, logging, overexploitation, and invasive alien species.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hoffmann, Michael -- Hilton-Taylor, Craig -- Angulo, Ariadne -- Bohm, Monika -- Brooks, Thomas M -- Butchart, Stuart H M -- Carpenter, Kent E -- Chanson, Janice -- Collen, Ben -- Cox, Neil A -- Darwall, William R T -- Dulvy, Nicholas K -- Harrison, Lucy R -- Katariya, Vineet -- Pollock, Caroline M -- Quader, Suhel -- Richman, Nadia I -- Rodrigues, Ana S L -- Tognelli, Marcelo F -- Vie, Jean-Christophe -- Aguiar, John M -- Allen, David J -- Allen, Gerald R -- Amori, Giovanni -- Ananjeva, Natalia B -- Andreone, Franco -- Andrew, Paul -- Aquino Ortiz, Aida Luz -- Baillie, Jonathan E M -- Baldi, Ricardo -- Bell, Ben D -- Biju, S D -- Bird, Jeremy P -- Black-Decima, Patricia -- Blanc, J Julian -- Bolanos, Federico -- Bolivar-G, Wilmar -- Burfield, Ian J -- Burton, James A -- Capper, David R -- Castro, Fernando -- Catullo, Gianluca -- Cavanagh, Rachel D -- Channing, Alan -- Chao, Ning Labbish -- Chenery, Anna M -- Chiozza, Federica -- Clausnitzer, Viola -- Collar, Nigel J -- Collett, Leah C -- Collette, Bruce B -- Cortez Fernandez, Claudia F -- Craig, Matthew T -- Crosby, Michael J -- Cumberlidge, Neil -- Cuttelod, Annabelle -- Derocher, Andrew E -- Diesmos, Arvin C -- Donaldson, John S -- Duckworth, J W -- Dutson, Guy -- Dutta, S K -- Emslie, Richard H -- Farjon, Aljos -- Fowler, Sarah -- Freyhof, Jorg -- Garshelis, David L -- Gerlach, Justin -- Gower, David J -- Grant, Tandora D -- Hammerson, Geoffrey A -- Harris, Richard B -- Heaney, Lawrence R -- Hedges, S Blair -- Hero, Jean-Marc -- Hughes, Baz -- Hussain, Syed Ainul -- Icochea M, Javier -- Inger, Robert F -- Ishii, Nobuo -- Iskandar, Djoko T -- Jenkins, Richard K B -- Kaneko, Yoshio -- Kottelat, Maurice -- Kovacs, Kit M -- Kuzmin, Sergius L -- La Marca, Enrique -- Lamoreux, John F -- Lau, Michael W N -- Lavilla, Esteban O -- Leus, Kristin -- Lewison, Rebecca L -- Lichtenstein, Gabriela -- Livingstone, Suzanne R -- Lukoschek, Vimoksalehi -- Mallon, David P -- McGowan, Philip J K -- McIvor, Anna -- Moehlman, Patricia D -- Molur, Sanjay -- Munoz Alonso, Antonio -- Musick, John A -- Nowell, Kristin -- Nussbaum, Ronald A -- Olech, Wanda -- Orlov, Nikolay L -- Papenfuss, Theodore J -- Parra-Olea, Gabriela -- Perrin, William F -- Polidoro, Beth A -- Pourkazemi, Mohammad -- Racey, Paul A -- Ragle, James S -- Ram, Mala -- Rathbun, Galen -- Reynolds, Robert P -- Rhodin, Anders G J -- Richards, Stephen J -- Rodriguez, Lily O -- Ron, Santiago R -- Rondinini, Carlo -- Rylands, Anthony B -- Sadovy de Mitcheson, Yvonne -- Sanciangco, Jonnell C -- Sanders, Kate L -- Santos-Barrera, Georgina -- Schipper, Jan -- Self-Sullivan, Caryn -- Shi, Yichuan -- Shoemaker, Alan -- Short, Frederick T -- Sillero-Zubiri, Claudio -- Silvano, Debora L -- Smith, Kevin G -- Smith, Andrew T -- Snoeks, Jos -- Stattersfield, Alison J -- Symes, Andrew J -- Taber, Andrew B -- Talukdar, Bibhab K -- Temple, Helen J -- Timmins, Rob -- Tobias, Joseph A -- Tsytsulina, Katerina -- Tweddle, Denis -- Ubeda, Carmen -- Valenti, Sarah V -- van Dijk, Peter Paul -- Veiga, Liza M -- Veloso, Alberto -- Wege, David C -- Wilkinson, Mark -- Williamson, Elizabeth A -- Xie, Feng -- Young, Bruce E -- Akcakaya, H Resit -- Bennun, Leon -- Blackburn, Tim M -- Boitani, Luigi -- Dublin, Holly T -- da Fonseca, Gustavo A B -- Gascon, Claude -- Lacher, Thomas E Jr -- Mace, Georgina M -- Mainka, Susan A -- McNeely, Jeffery A -- Mittermeier, Russell A -- Reid, Gordon McGregor -- Rodriguez, Jon Paul -- Rosenberg, Andrew A -- Samways, Michael J -- Smart, Jane -- Stein, Bruce A -- Stuart, Simon N -- New York, N.Y. -- Science. 2010 Dec 10;330(6010):1503-9. doi: 10.1126/science.1194442. Epub 2010 Oct 26.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉IUCN SSC Species Survival Commission, c/o United Nations Environment Programme World Conservation Monitoring Centre, 219 Huntingdon Road, Cambridge CB3 0DL, UK. mike.hoffmann@iucn.org〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/20978281" target="_blank"〉PubMed〈/a〉
    Keywords: Amphibians ; Animals ; *Biodiversity ; Birds ; *Conservation of Natural Resources ; *Ecosystem ; Endangered Species/statistics & numerical data/trends ; Extinction, Biological ; Introduced Species ; Mammals ; Population Dynamics ; *Vertebrates
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2019-08-13
    Description: The Inflatable Reentry Vehicle Experiment II launched August 17, 2009, from NASA Wallops Flight Facility. The three mission objectives were to demonstrate inflation and re-entry survivability, assess the thermal and drag performance of the reentry vehicle, and to collect flight data for comparison with analysis and design techniques used in vehicle development. The flight was a complete success, with the re-entry vehicle separating cleanly from the launcher, inflating as planned, and demonstrating stable flight through reentry and descent while on-board systems telemetered video and flight performance data to the ground.
    Keywords: Spacecraft Design, Testing and Performance
    Type: NF1676L-10402 , International Planetary Probe Workshop 2010 (IPPW-7); Jun 14, 2010 - Jun 18, 2010; Barcelona, Spain; Spain
    Format: application/pdf
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