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  • Lepidoptera  (167)
  • Bone
  • Cyanobacteria
  • Isoptera
  • bioavailability
  • Springer  (370)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 17 (1980), S. 111-116 
    ISSN: 1432-1041
    Keywords: zimelidine ; norzimelidine ; antidepressants ; pharmacokinetics ; bioavailability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The systemic availability of a new antidepressant, zimelidine, and of its pharmacologically active metabolite, norzimelidine, was studied in six healthy male volunteers. Three single doses of zimelidine (25 mg and 100 mg orally and 25 mg i.v.) and two single doses of norzimelidine (25 mg orally and i. v.) were given to each volunteer allowing at least seven days between administrations. Plasma concentrations of zimelidine and norzimelidine were determined in serial blood samples by HPLC. Following oral zimelidine peak plasma concentrations of the metabolite were attained about 3 h after dosing. Oral administration of norzimelidine itself resulted in a plasma concentration profile for this compound that was similar to that observed after oral zimelidine. Utilising the plasma concentration data following intravenous infusion of each compound, the elimination half-lives for zimelidine and norzimelidine were calculated to be 5.1 h (range 4.3–6.0) and 15.5 h (range 10.6–22.9) respectively. The total body clearances of the 2 compounds were similar at 0.52 l · min−1 (range 0.26–0.70) for zimelidine and 0.56 l · min−1 (range 0.28–0.83) for norzimelidine. The substantially longer elimination half-life of norzimelidine was apparently the result of a larger volume of distribution (9.4 l · kg−1; range 7.8–11.4) for this metabolite, as compared to zimelidine (3.21 · kg−1; range 1.6–4.9). The calculated bioavailability of zimelidine was 26% (range 9.1–39) after the 25 mg oral dose, and 29% (range 14–46) after the 100 mg dose. The bioavailability of norzimelidine was 66% (range 36–91). However, oral administration of zimelidine resulted in as much or more norzimelidine reaching the systemic circulation, as the oral administration of norzimelidine itself. This is important as a large part of the activity of the drug may be due to the metabolite.
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  • 2
    ISSN: 1570-7458
    Keywords: rice leaffolder ; Cnaphalocrocis medinalis ; Lepidoptera ; Pyralidae ; (Z)-11-hexadecenyl acetate ; (Z)-13-octadecenyl acetate ; (Z)-13-octadecen-1-ol ; octadecyl acetate ; sex pheromone ; attractant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Analysis of ovipositor washings from virgin femaleCnaphalocrocis medinalis Guenée (Lepidoptera: Pyralidae) of Indian origin by linked gas chromatography and electroantennography indicated the presence of three electrophysiologically-active compounds. These were identified on the basis of their gas chromatographic retention times and mass spectra as (Z)-11-hexadecenyl acetate, (Z)-13-octadecenyl acetate and (Z)-13-octadecen-1-ol with (Z)-13-octadecenyl acetate present in amounts of between 0.25 and 1.5 ng per ovipositor and the other two components at less than 10% of this. Trace quantities of octadecyl acetate were identified by mass spectrometry but no electroantennographic responses were observed to this compound. Field trials conducted with a range of blends of the three electrophysiologically-active compounds showed that blends containing between 5% and 30% (Z)-11-hexadecenyl acetate in (Z)-13-octadecenyl acetate dispensed from either white rubber septa or polythene vials were more attractive to male moths than a virgin female moth. Addition of (Z)-13-octadecen-1-ol reduced attractiveness to male moths in the blends and concentrations tested.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Calcified tissue international 12 (1973), S. 73-90 
    ISSN: 1432-0827
    Keywords: Bone ; Mineral ; Properties ; Deproteination ; Hydrazine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Description / Table of Contents: Résumé Une méthode, utilisant 95% d'hydrazine, permet de déprotéiniser et de déshydrater légèrement l'os dans des conditions presqu'anhydres, avec une élévation de température modérée. Cette méthode ne provoque que des modifications chimiques mineures, sans altération des propriétés structurales de la phase minérale. Les résultats physico-chimiques démontrent que bien que les cristaux d'os de rat sont viosins de cristaux synthétiques témoins constitués dans des milieux, riches en carbonate plutôt qu'en hydroxyde, l'apatite osseux de rat ne parait pas analogue à des modèles cristallins connus ou imaginés. Des déterminations de bande infra-rouge CO 3 2− , réalisées à partir de spectre d'os total, semblent faussées par la présence de bandes d'absorption protéique. L'absorption d'HPO 4 2− est étudiée à l'aide de spectres infra-rouges de minéral osseux de jeunes rats. Des comparaisons détaillées en diffraction par raysons X d'os déprotéinisé de rats, avant et après hydrolyse, démontrent nettement la présence de phosphate de calcium amorphe. La microscopie électronique indique que de petits cristaux d'apatite dans l'os de rat sont susceptibles de contribuer au pool minéral amorphe en diffraction en rayons X. La microscopie électronique montre des plages de minéral osseux de rat où des cristaux d'apatite en forme de plaque, présentent une maille cristalline avec axe C malgré l'élimination de leur matrice fibreuse.
    Abstract: Zusammenfassung Es wird eine Methode beschrieben, wobei durch Anwendung von 95% Hydrazin ohne Wasserzugabe und mit nur geringem Erhitzen dem Knochen das gesamte Protein und ein kleiner Teil des Wassers entzogen wird. Diese Methode führte nur zu geringen chemischen Veränderungen und veränderte die strukturellen Eigenschaften der Mineralphase in keiner Weise. Physikochemische Daten wurden erbracht, welche zeigen, daß — obwohl die Kristalle von Rattenknochen den synthetischen Kontrollen (in Karbonat- und nicht hydroxydreichen Medien hergestellt) eher gleichen — Apatit aus Rattenknochen nicht auf sinnvolle Weise mittels bekannten oder postulierten Kristallmodellen interpretiert werden kann. CO 3 2− -Infrarotbandenzuteilungen, welche von Spektren aus dem Gesamtknochen gemacht wurden, geben wegen der Anwesenheit von Proteinabsorptionsbändern falsche Resultate. Die Absorption von HPO 4 2− wurde in den Infrarotspektren von Knochenmineral aus jungen Ratten beobachtet. Ein Vergleich der detaillierten Röntgendiffraktion von deproteinisiertem Rattenknochen vor und nach der Hydrolyse wies deutlich auf die Anwesenheit von amorphem Calciumphosphat hin. Die Elektronenmikroskopie zeigte kleine Apatitkristalle im Rattenknochen, welche zum Gesamtmineralpool beitragen könnten, der bei der Röntgendiffraktion amorph ist. Die Elektronenmikroskopie zeigte auch Gebiete im Rattenknochenmineral, wo plättchenartige Apatitkristalle eine deutlichec-Achsenorientierung beibehielten, obwohl ihre fibröse Matrix entfernt worden war.
    Notes: Abstract A method is described employing 95% hydrazine which completely deproteinates and slightly dehydrates bone under nearly anhydrous conditions with only moderate heating. This method induced only minor chemical changes and no alterations in structural properties of the mineral phase. Physicochemical data are presented demonstrating that although rat bone crystals more closely resemble synthetic controls made in carbonate-rather than hydroxide-rich media, rat bone apatite cannot be interpreted in terms of known or postulated crystal models in any meaningful fashion. CO 3 2− infrared band assignments made from spectra of whole bone are shown to be in error due to the presence of protein absorption bands. Absorotion of HPO 4 2− was observed in infrared spectra of young rat bone mineral. Detailed X-ray diffraction comparisons of deproteinated rat bone before and after hydrolysis clearly demonstrated the presence of amorphous calcium phosphate. Electron microscopy indicated that very small apatite crystals were present in rat bone which might also contribute to the overall mineral pool amorphous to X-ray diffraction. Electron microscopy also showed domains in rat bone mineral where plate-like apatite crystals maintained a netc-axis orientation despite the removal of their fibrous matrix.
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  • 4
    ISSN: 1573-1561
    Keywords: Spotted bollworm ; Earias vittella ; spiny bollworm ; Earias insulana ; Lepidoptera ; Noctuidae ; gas chromatography ; electroantennography ; pheromone traps ; hexadecanal ; (Z)-11-hexadecenal ; (E,E)-10,12-hexadecadienal ; (Z,E)-10,12-hexadecadienal ; (E,Z)-10,12-hexadecadienal ; octadecanal ; (Z)-11-octadecenal ; (E,E)-10,12-hexadecadien-1-ol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Ovipositor washings from virgin femaleEarias vittella (F.) (Lepidoptera: Noctuidae) moths were examined by gas chromatography (GC) linked to electroantennography (EAG). Six components were detected by the male moth. These were identified by comparison of their retention times with those of a range of synthetic standards on fused silica capillary GC columns as hexadecanal, (Z)-11-hexadecenal, (E,E)-10,12-hexadecadienal, octadecanal, (Z)-11-octadecenal, and (E,E)-10,12-hexadecadien-1-ol in 1∶2∶10∶2∶4∶1 ratio. Field testing in Pakistan showed that a 2∶10∶2 mixture of (Z)-11-hexadecenal, (E,E)-10,12-hexadecadienal, and (Z)-11-octadecenal was as attractive to maleE. vittella moths as the six-component mixture and equal in attractiveness to a virgin female moth. Omitting (Z)-11-hexadecenal or (Z)-11-octadecenal greatly reduced this attractiveness. It was found that synthetic lures must be protected from sunlight to prevent loss of attractiveness caused by isomerization of the conjugated diene aldehyde, and addition of (E,Z)-10,12-hexadecadienal, one of the products of isomerization, was shown to reduce attractiveness significantly. During this work, a 10∶1 mixture of (E,E)-10, 12-hexadecadienal and (Z)-11-hexadecenal was shown to be as attractive toE. insulana (Boisd.) male moths as a virgin female moth, and the attractiveness of this mixture was further increased by addition of (E,Z)-10,12-hexadecadienal.
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  • 5
    ISSN: 1573-5036
    Keywords: Blue-green algae ; Cyanobacteria ; Osmotic responses ; Salinity tolerance ; Spirulina
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary Photosynthetic, prokaryotic blue-green algae (cyanobacteria) occur in a wide range of natural habitats of diverse ionic composition and as such, represent an important source of biological material for biosolar energy conversion programs using saline water. The gasvacuolate, filamentous Spirulina is grown in ‘seminatural’ culture in Lake Texcoco, Mexico, as a major source of single-cell protein for animal nutrition. Pilot-scale trials in other areas of the world have also demonstrated the suitability of blue-green algae, including Spirulina, for growth under brackish conditions. The carbohydrate accumulation profiles of blue-green algae differ in isolates from freshwater, marine and hypersaline habitats, with a trend towards sucrose or trehalose accumulation in stenohaline freshwater strains grown in media containing NaCl, while euryhaline and marine forms frequently accumulate glucosylglycerol. Many halotolerant isolates from hypersaline habitats accumulate glycinebetaine in response to osmotic stress. This knowledge may provide scope for future improvement in the N2 fixation rates of blue-green algae in saline media, using betaine-accumulating N2-fixing strains in preference to other, saltsensitive isolates.
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  • 6
    ISSN: 1572-8889
    Keywords: trail following ; 5β-cholestane-3-one ; pheromone ; cooperative foraging ; social caterpillar ; bolsa ; silk ; Pieridae ; Eucheira ; Lepidoptera
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The larva of the Madrone butterfly Eucheira socialis (Lepidoptera: Pieridae) secretes a trail pheromone from the ventral surface of the posterior tip of its abdomen. Caterpillars mark trails by bringing the secretory site into brief contact with the substrate during a locomotive cycle. Foragers mark most heavily when they move onto new branches and little, if at all, when they move over established trails or when they return to the communal shelter after feeding. The caterpillars make careful comparisons of alternative pathways at choice points and select newer and stronger trails over older and weaker trails. Differential marking of new and established trails during nightly forays, coupled with sensory discrimination of trails by strength and age, leads colonies to abandon old trails in favor of new trails. When applied at a rate as low as 2.5 × 10 −10 g/mm, caterpillars followed synthetic trails prepared from 5β-cholestane-3-one, a trail pheromone previously reported from the tent caterpillars (Malacosoma spp.). Although both Eucheira and Malacosoma mark with the tip of the abdomen and have near-identical sensitivites to 5β-cholestane-3-one, our study shows that Eucheira employs a relatively unsophisticated system of trail-based communication and does not recruit to food. The trail-based communication system of Eucheira appears to represent an early stage in the evolution of cooperative foraging that is derived from, and motivationally linked to, conflict behavior.
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  • 7
    ISSN: 1572-8889
    Keywords: radar tracking ; harmonic radar ; foraging flight ; Lepidoptera ; Agrotis segetum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Entomologia experimentalis et applicata 30 (1981), S. 123-127 
    ISSN: 1570-7458
    Keywords: Sex Pheromones ; Repellent ; Heliothis armigera ; Heliothis zea ; Lepidoptera ; Noctuidae ; cotton bollworm ; corn earworm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Résumé L'examen en olfactomètre a porté sur les réactions face à d'autres femelles de la même espèce, de femelles vierges ou ayant copulé d'Heliothis armigera Hübner et H. zea Boddie. Le lot comprenait 8 femelles, vierges ou ayant copulé en présence d'une femelle vierge ou ayant copulé. Les 4 combinaisons possibles de femelles vierges et de femelles ayant copulé ont été examinées avec 12 répétitions pour chaque espèce. Un extrait de l'extrémité de l'abdomen de femelles vierges d'une espèce a été présenté aux femelles de l'autre espèce pour examiner les possibilités de réactions interspécifiques aux phéromones. Pour chaque espèce, les réactions interspécifiques de répulsion entre femelles ont été hautement significatives par rapport aux témoins, à l'exception toutefois des réactions de femelle ayant copulé face à des femelles ayant elles aussi copulé. Les répulsions moyennes chez H. armigera et H. zea pour les 8 femelles de chaque expérience ont été: a) vierges en présence d'une vierge: 7,33 et 7,66; b) vierges en présence d'une femelles ayant copulé: 5,76 et 5,58; c) femelles ayant copulé en présence d'une vierge: 4,67 et 4,83. Les différences sont hautement significatives entre chaque paire de moyennes et entre chaque paire et le lot témoin; 3,17; 3,17; 3,42; 4,00 pour H. armigera; 3,17; 3,50; 2,83 et 3,75 pour H. zea. Les femelles vierges des deux espèces, H. armigera et H. zea ont présenté une réaction de répulsion en présence d'un extrait de l'abdomen de l'autre espèce; les répulsions moyennes étant respectivement 5,53 et 5,33 contre 3,83 et 3,58 pour le lot trémoin. On peut en conclure que ces répulsions doivent entraîner une tendance à la répartition uniforme.
    Notes: Abstract An olfactometer was used to determine the effect of pheromones released by females of the bollworms Heliothis armigera (Hübner) and H. zea (Boddie) on females of the same species. Four combinations of virgin and mated females were tested for repellency of one to the other. Evidence is presented that females of the two bollworms were repelled by females of the same species. In addition, extracts of virgin female abdomens of each species repelled virgin females of the other species.
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  • 9
    ISSN: 1570-7458
    Keywords: Lepidoptera ; Pyralidae ; navel orangeworm ; Amyelois transitella ; pheromone mimic ; mating disruption ; Z,Z-1,12,14-heptadecatriene ; Z,Z-11,13-hexadecadienal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Résumé Le Z-Z-1,12,14-heptacécatriène, qui mime l'aldéhyde Z-Z-11,13-hexadécadénial, principal composé de la phéromone de A. transitella Walker, a été essayé pour interrompre les accouplements dans la nature. Un conditionnement avec plastique stratifié a mieux dispersé le triène que la présentation en capsules de polyéthylène. Comme dans le cas des autres produits examinés précédemment, ce triène a interrompu l'attraction sexuelle (réduction du nombre de mâles capturés dans les pièges, réduction du nombre d'accouplements) de A. transitella dans les vergers d'amandiers, pendant moins longtemps que l'aldéhyde. Placé dans des pièges contenant des femelles vierges, il est efficace comme l'aldehyde pendant 5 semaines, pendant 3 semaines lorsqu'il est placé autour des pièges et pendant 13 jours quand il est utilisé dans des parcelles de 9 arbres. Des essais ultérieurs avec d'autres présentations et des quantités plus élevées de triène devraient montrer si ce produit peut être utilisé pour l'interruption des accouplements. Les analogues de phéromones ont généralement une plus grande stabilité et un coût de synthèse moins élevé que les aldéhydes.
    Notes: Abstract A novel olefinic analog, Z,Z-1,12,14-heptadecatriene, was synthesized from Z,Z-11,13-hexadecadienal, a major pheromone component of the navel orangeworm, Amyelois transitella (Walker) (Lepidoptera: Pyralidae), and evaluated as a potential disruptant of mating communication in commercial almond orchards. The effectiveness of the triene as a disruptant was compared to that of the aldehyde by evaluating the reduction in captures of feral males in female-baited traps and the reduction in mating success for females. The triene was highly effective in bringing about reductions in male captures in traps in all tests relative to controls. This effectiveness lasted as long as 5 weeks in one test and was influenced by type of dispenser, release rate and proximity of dispensers to female-baited traps. In none of the tests did the triene outperform the aldehyde in reducing male captures. The results of mating success tests showed the triene to be ineffective relative to controls (26% reduction) while the aldehyde yielded 100% reductions in matings during a 6-day period.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Materials research innovations 3 (2000), S. 313-323 
    ISSN: 1433-075X
    Keywords: Keywords Glass ; Cell cycle ; Genes ; Bone ; Bioactive materials ; Osteogenesis ; Prostheses ; Omplants ; Ageing ; Osteoblasts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  Many of the present generation biomaterials are still based upon the early concept that implantable materials should be bioinert and therefore designed to evoke minimal tissue response, if none. However, a growing body of clinical data demonstrates that the long survivability of these materials is hampered by high rates of failure, which is primarily attributed to interfacial instability. It has therefore become understood that this approach is not optimal. Modern approaches implicate the use of biomaterials that can actively interact with tissues and induce their intrinsic repair and regenerative potential. This involves control over the cell cycle, the molecular framework that controls cell proliferation and differentiation. Class A bioactive glass-ceramic materials were the first materials shown to endorse these properties and, depending upon the rate of resorption and release of ions, can create chemical gradients with specific biological actions over cells and tissues. Optimising this bioactive regenerative capacity of Bioactive glass-ceramics offers great hope for producing biomaterials that can stimulate growth, repair, and regeneration of any human tissue.
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