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  • Chemical Engineering  (7)
  • Analytical Chemistry and Spectroscopy  (2)
  • Animals
  • 1980-1984  (10)
  • 1983  (10)
  • 1
    Publication Date: 1983-01-14
    Description: Immunoreactive corticotropin-releasing factor (CRF) and dynorphin-(I-8) were visualized in rat hypothalamus by immunohistofluorescence with specific antibodies. In brains from colchicine-treated, adrenalectomized rats, neuronal perikarya with immunoreactive CRF were observed in the paraventricular nucleus of the hypothalamus. The CRF occurred together with the dynorphin-(1-8). However, the CRF immunoreactivity occurred only in a subpopulation of the dynorphin-(1-8) immunoreactive cells. These findings suggest that there may be a functional interrelationship of CRF with dynorphin-related opioid peptides and provide further evidence that neurons may contain more than one bioactive substance.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Roth, K A -- Weber, E -- Barchas, J D -- Chang, D -- Chang, J K -- New York, N.Y. -- Science. 1983 Jan 14;219(4581):189-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6129700" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Corticotropin-Releasing Hormone/immunology/*metabolism ; Dynorphins ; Endorphins/immunology/*metabolism ; Fluorescent Antibody Technique ; Hypothalamus/cytology/*metabolism ; Neurons/metabolism ; Paraventricular Hypothalamic Nucleus/metabolism ; Peptide Fragments/metabolism ; Rats
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 6 (1983), S. 617-620 
    ISSN: 0935-6304
    Keywords: High-performance thin-layer chromatography, HPTLC ; Reversed-phase ; Octadecyl-bonded silica gel ; Bile acid methyl esters ; Methyl 5β -cholanates ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A comparative study is reported on separation of series of mono-, di-, and trisubstituted methyl 5β-cholanates, which differ only in the position and stereochemistry of hydroxyl or keto groups at position and stereochemistry of hydroxyl or keto groups at positions C-3, C-7, and/or C-12, by reversed-phase [with chemically-bonded (C-18) silica gel] and normal-phase (silica gel) high-performance thin-layer chromatography (HPTLC). Methnol (or acetonitrile)/water systems were employed as mobile phase. Reversed-phase HPTLC found to be particulary effective for separation of the stereoisomers of di- and trisubstituted compounds whereas the less polar monosubstituted isomers are well resolved in normal-phase HPTLC.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 29 (1983), S. 132-136 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The dynamic pulse-response technique was used to measure effective diffusivities under nonreacting conditions in two, unsulfided, extrudate-type, hydrodesulfurization catalyst pellets of different porosities. Pore-volume distribution data showed a bidisperse pore structure with a broad pore-size range (100 μm to 3 nm).The main purpose of the study was to evaluate various methods for calculating the tortuosity factor, τ. For this particular catalyst, the most constant and unreasonable values of τ were obtained by supposing that diffusion occurred in all the pore volume (micro and macropores) and by summing the combined Knudsen and bulk contributions over each increment of pore volume.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 29 (1983), S. 846-853 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A multiscale analysis based on two widely different length scales that exist instagnant two-phase media is carried out to investigate diffusion and conduction in periodic and random systems. A variational form of the resulting unit cell equations allows one to demonstrate its equivalence to the cell equations of other independent approaches, thus unifying these widely different methods. The variational approach is also shown to facilitate numerical studies and to provide a link between random and periodic media by yielding an upper bound for the effective diffusivity in random media in terms of the periodic one.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 29 (1983), S. 1039-1041 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 29 (1983), S. 910-914 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Hollow-fiber device has been used to investigate the effect of ultrafiltration swing on the performance of membrane-enzyme reactor. Experiments with β-galactosidase and ONPG have shown that bidirectional ultrafiltration induced by pulsatile flow gives rise to an increase in conversion relative to that obtained at steady operation without ultrafiltration swing. This increase apparently comes from the enhanced mass transfer due to ultrafiltration.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 29 (1983), S. 645-651 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A new membrane enzyme reactor system is proposed, and its performance is analytically and numerically examined by operational modes. This membrane-separated, two-compartmental reactor is operated in a cyclic manner such that ultrafiltration swing is induced either by a pulsatile flow or by an alternating pressure difference. Substrate and product solutins are permeable to the membrane while enzyme is impermeable. In one reservoir, enzyme solution is stored into which substrate is supplied by diffusion-coupled ultrafiltration and product is removed by the same mechanism into the substrate compartment, which is similar to CSTR in view of fluid mixing and continuous inlet-outlet flows, but differs from CSTR in a sense that reaction takes place only in the enzyme compartment.The governing model equations are derived and their analytical solutions are obtained for fast reaction and high ultrafiltration with first-order kinetics. In addition, nonlinear Michaelis-Menten kinetics problem is solved numerically. As a result, we have found that the system can increase the conversion substantially compared with previous diffusion-moderated enzyme reactors where diffusion very often can limit the extent of conversion.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 29 (1983), S. 95-100 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A principal mechanism for rapid mixing and fragmentation in vapor explosions, such as have occurred in the LNG, aluminum, steel and paper industries, is thought to be nonlinear Taylor instability. An analysis, based on a generalized coordinate method developed by Dienes for a fluid with an arbitrary constitutive law, is here extended to a two-fluid model, with or without mass transfer between the fluids. Numerical results indicate that in a steam-water system entrainment starts in times of order 10-4s at 100 G acceleration normal to the interface. For gas-liquid systems the presence of the second fluid changes the instability growth only slightly. Condensation of steam, even when limited only by the kinetic theory interfacial resistance, also has minor effects on the growth rate. However, condensation on the entrained drops will have a major effect on the acceleration.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 29 (1983), S. 699-700 
    ISSN: 0001-1541
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 21 (1983), S. 305-309 
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Carbon-13 NMR signals were assigned for the complete set of the 26 theoretically possible isomers of methyl 5β-cholanates having one to three hydroxy groups at positions C-3, C-7 and/or C-12 in the nucleus. Substituent effects on the 13C NMR shielding data serving to characterize the position and configuration of the hydroxy groups are discussed.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
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