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Digitale Medien

2,2',6,6'-Tetraethoxycarbonyl-4,4'-bithiapyranylidene (1982)

Darocha, B. F. ; Titus, D. D. ; Sandman, D. J. ; [weitere]

Copenhagen : International Union of Crystallography (IUCr)

Acta crystallographica 38 (1982), S. 2267-2269

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ISSN: 1600-5740

Quelle: Crystallography Journals Online : IUCR Backfile Archive 1948-2001

Thema: Chemie und Pharmazie , Geologie und Paläontologie , Physik

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1107/S0567740882008504

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2

Digitale Medien

The structure of the ether solvate of cis-μ-[benzyl(phenyl)vinylidene]-μ-carbonyl-bis[carbonyl(η5-cyclopentadienyl)iron(0)](Fe–Fe), cis-Fe2(CO)2(η5-C5H5)2(μ-CO)[μ-C=C(C6H5)CH2C6H5].C4H10O (1982)

Hossain, M. B. ; Hanlon, D. J. ; Marten, D. F. ; [weitere]

Copenhagen : International Union of Crystallography (IUCr)

Acta crystallographica 38 (1982), S. 1457-1461

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ISSN: 1600-5740

Quelle: Crystallography Journals Online : IUCR Backfile Archive 1948-2001

Thema: Chemie und Pharmazie , Geologie und Paläontologie , Physik

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1107/S0567740882006141

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3

Digitale Medien

Blood-materials interactions: The minimum interfacial free energy and the optimum polar/apolar ratio hypotheses (1982)

Coleman, D. L. ; Gregonis, D. E. ; Andrade, J. D.

Hoboken, NJ : Wiley-Blackwell

Journal of Biomedical Materials Research 16 (1982), S. 381-398

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ISSN: 0021-9304

Schlagwort(e): Chemistry ; Polymer and Materials Science

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Medizin , Technik allgemein

Notizen: Numerous hypotheses exist to explain observed blood-materials interactions. It is the purpose of this article to test two popular hypotheses, namely, the minimum interfacial free energy hypothesis and the optimum polar/apolar ratio hypothesis. Methacrylate polymers and copolymers were characterized using the captive bubble underwater contact angle method; bulk water content was determined by gravimetric methods; streaming potential measurements were made; and surface roughness and possible particulate contamination were evaluated by reflected light microscopy. In vitro blood tests include whole blood clotting time measurements on polymer-coated tubes; centrifugal force platelet adhesion on polymer-coated coverslips; and a measure of the partial thromboplastin time, Russell's viper venom time (Stypven time), and the prothrombin time of native whole blood exposed to polymer-coated microscope slides. Results suggest that platelet adhesion correlates in the opposite direction of whole blood clotting time and partial thromboplastin time, emphasizing the need for a multiparameter approach to blood-materials testing. Based on these tests the minimum interfacial free energy hypothesis is not supported. In fact, the data suggest the opposite to be true. It is apparent that platelet adhesion can be a misleading indicator of blood compatibility. Neither hypotheses can explain the apparent conflict between the platelet adhesion data and the coagulation time data.

Zusätzliches Material: 9 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/jbm.820160407

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4

Digitale Medien

Perturbation of the switch-on of transcriptase activity in intermediate subviral particles from reovirus (1982)

Borsa, J. ; Sargent, M. D. ; Ewing, D. D. ; [weitere]

New York, NY [u.a.] : Wiley-Blackwell

Journal of Cellular Physiology 112 (1982), S. 10-18

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ISSN: 0021-9541

Schlagwort(e): Life and Medical Sciences ; Cell & Developmental Biology

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Biologie , Medizin

Notizen: Intermediate subviral particles (ISVP) derived from reovirus represent a simple model system for the switch-on of transcriptase function. In such particles the endogenous transcriptase is present in a switched-off form, one step removed from the switched-on state. Switch-on of transcriptase function is an active process in this system and can be triggered by K+ ions. A variety of agents which affect gene expression in cells were tested for an effect on switch-on in ISVP. Marked effects on switch-on in ISVP were observed with a diverse group of test agents, including DMSO and other solvents, BUdR, TdR, caffeine, theophylline, and temperature. The correlation in response between ISVP and cells suggests that the ISVP system may be useful as a model for studying the biochemical mechanisms underlying the perturbative effects of such agents on gene expression in cells.

Zusätzliches Material: 14 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/jcp.1041120104

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