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  • Articles  (29)
  • *Ecosystem  (19)
  • Transfection
  • American Association for the Advancement of Science (AAAS)  (29)
  • 2000-2004  (29)
  • 2000  (29)
  • Science. 287(5452): 443-9.  (1)
  • Science. 287(5454): 857-9.  (1)
  • Science. 287(5458): 1647-51.  (1)
  • Science. 287(5459): 1770-4.  (1)
  • Science. 287(5460): 2004-6.  (1)
  • Science. 288(5467): 874-7.  (1)
  • Science. 288(5468): 941-2.  (1)
  • Science. 288(5471): 1575-6.  (1)
  • Science. 288(5472): 1828-32.  (1)
  • Science. 288(5473): 1969-70.  (1)
  • Science. 288(5473): 2042-5.  (1)
  • Science. 288(5474): 2135-6.  (1)
  • Science. 288(5474): 2219-22.  (1)
  • Science. 288(5474): 2226-30.  (1)
  • Science. 289(5478): 395-6.  (1)
  • Science. 289(5480): 762-5.  (1)
  • Science. 289(5481): 869.  (1)
  • Science. 289(5482): 1159-64.  (1)
  • Science. 289(5483): 1255.  (1)
  • Science. 289(5483): 1349-52.  (1)
  • 25
  • Biology  (29)
Collection
  • Articles  (29)
Publisher
  • American Association for the Advancement of Science (AAAS)  (29)
Years
  • 2000-2004  (29)
Year
Journal
  • 1
    Publication Date: 2000-03-17
    Description: The effects of increasing carbon dioxide (CO2) and climate on net carbon storage in terrestrial ecosystems of the conterminous United States for the period 1895-1993 were modeled with new, detailed historical climate information. For the period 1980-1993, results from an ensemble of three models agree within 25%, simulating a land carbon sink from CO2 and climate effects of 0.08 gigaton of carbon per year. The best estimates of the total sink from inventory data are about three times larger, suggesting that processes such as regrowth on abandoned agricultural land or in forests harvested before 1980 have effects as large as or larger than the direct effects of CO2 and climate. The modeled sink varies by about 100% from year to year as a result of climate variability.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schimel, D -- Melillo, J -- Tian, H -- McGuire, A D -- Kicklighter, D -- Kittel, T -- Rosenbloom, N -- Running, S -- Thornton, P -- Ojima, D -- Parton, W -- Kelly, R -- Sykes, M -- Neilson, R -- Rizzo, B -- New York, N.Y. -- Science. 2000 Mar 17;287(5460):2004-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Max-Planck-Institute for Biogeochemistry, Postfach 10 01 64, D-07701 Jena, Germany. dschimel@bgc-jena.mpg.de〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10720324" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture ; Atmosphere ; Carbon/*metabolism ; Carbon Dioxide/*metabolism ; *Climate ; Computer Simulation ; *Ecosystem ; Geography ; Trees ; United States
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2000-08-12
    Description: Ecosystems are capital assets: When properly managed, they yield a flow of vital goods and services. Relative to other forms of capital, however, ecosystems are poorly understood, scarcely monitored, and--in many important cases--undergoing rapid degradation. The process of economic valuation could greatly improve stewardship. This potential is now being realized with innovative financial instruments and institutional arrangements.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Daily, G C -- Soderqvist, T -- Aniyar, S -- Arrow, K -- Dasgupta, P -- Ehrlich, P R -- Folke, C -- Jansson, A -- Jansson, B -- Kautsky, N -- Levin, S -- Lubchenco, J -- Maler, K G -- Simpson, D -- Starrett, D -- Tilman, D -- Walker, B -- New York, N.Y. -- Science. 2000 Jul 21;289(5478):395-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA. gdaily@leland.stanford.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10939949" target="_blank"〉PubMed〈/a〉
    Keywords: Australia ; Commerce ; Conservation of Natural Resources/*economics ; Costa Rica ; *Ecosystem ; Industry ; Investments
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 2000-03-04
    Description: The coupling mechanism between endoplasmic reticulum (ER) calcium ion (Ca2+) stores and plasma membrane (PM) store-operated channels (SOCs) is crucial to Ca2+ signaling but has eluded detection. SOCs may be functionally related to the TRP family of receptor-operated channels. Direct comparison of endogenous SOCs with stably expressed TRP3 channels in human embryonic kidney (HEK293) cells revealed that TRP3 channels differ in being store independent. However, condensed cortical F-actin prevented activation of both SOC and TRP3 channels, which suggests that ER-PM interactions underlie coupling of both channels. A cell-permeant inhibitor of inositol trisphosphate receptor (InsP3R) function, 2-aminoethoxydiphenyl borate, prevented both receptor-induced TRP3 activation and store-induced SOC activation. It is concluded that InsP3Rs mediate both SOC and TRP channel opening and that the InsP3R is essential for maintaining coupling between store emptying and physiological activation of SOCs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ma, H T -- Patterson, R L -- van Rossum, D B -- Birnbaumer, L -- Mikoshiba, K -- Gill, D L -- AR07592/AR/NIAMS NIH HHS/ -- HL55426/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 2000 Mar 3;287(5458):1647-51.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Biochemistry and Molecular Biology, University of Maryland, School of Medicine, Baltimore, MD 21201, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10698739" target="_blank"〉PubMed〈/a〉
    Keywords: Actins/metabolism ; Boron Compounds/pharmacology ; Calcium/*metabolism ; Calcium Channels/chemistry/*metabolism ; *Calcium Signaling ; Carbachol/pharmacology ; Cell Line ; Cell Membrane/metabolism ; Diglycerides/metabolism/pharmacology ; Endoplasmic Reticulum/*metabolism ; Enzyme Inhibitors/pharmacology ; Humans ; Inositol 1,4,5-Trisphosphate Receptors ; Ionomycin/pharmacology ; Macrocyclic Compounds ; Oxazoles/pharmacology ; Phosphoprotein Phosphatases/antagonists & inhibitors ; Receptors, Cytoplasmic and Nuclear/chemistry/*metabolism ; Strontium/metabolism ; TRPC Cation Channels ; Thapsigargin/pharmacology ; Transfection ; Type C Phospholipases/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 2000-09-09
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Huston, M A -- Aarssen, L W -- Austin, M P -- Cade, B S -- Fridley, J D -- Garnier, E -- Grime, J P -- Hodgson, J -- Lauenroth, W K -- Thompson, K -- Vandermeer, J H -- Wardle, D A -- New York, N.Y. -- Science. 2000 Aug 25;289(5483):1255.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10979839" target="_blank"〉PubMed〈/a〉
    Keywords: Biomass ; *Ecosystem ; Europe ; Fabaceae/growth & development ; *Plant Development ; Plants, Medicinal
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 2000-03-10
    Description: Scenarios of changes in biodiversity for the year 2100 can now be developed based on scenarios of changes in atmospheric carbon dioxide, climate, vegetation, and land use and the known sensitivity of biodiversity to these changes. This study identified a ranking of the importance of drivers of change, a ranking of the biomes with respect to expected changes, and the major sources of uncertainties. For terrestrial ecosystems, land-use change probably will have the largest effect, followed by climate change, nitrogen deposition, biotic exchange, and elevated carbon dioxide concentration. For freshwater ecosystems, biotic exchange is much more important. Mediterranean climate and grassland ecosystems likely will experience the greatest proportional change in biodiversity because of the substantial influence of all drivers of biodiversity change. Northern temperate ecosystems are estimated to experience the least biodiversity change because major land-use change has already occurred. Plausible changes in biodiversity in other biomes depend on interactions among the causes of biodiversity change. These interactions represent one of the largest uncertainties in projections of future biodiversity change.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sala, O E -- Chapin, F S 3rd -- Armesto, J J -- Berlow, E -- Bloomfield, J -- Dirzo, R -- Huber-Sanwald, E -- Huenneke, L F -- Jackson, R B -- Kinzig, A -- Leemans, R -- Lodge, D M -- Mooney, H A -- Oesterheld, M -- Poff, N L -- Sykes, M T -- Walker, B H -- Walker, M -- Wall, D H -- New York, N.Y. -- Science. 2000 Mar 10;287(5459):1770-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Ecology and Instituto de Investigaciones Fisiologicas y Ecologicas vinculadas a la Agricultura, Faculty of Agronomy, University of Buenos Aires, Avenida San Martin 4453, Buenos Aires 1417, Argentina. sala@ifeva.edu.ar〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10710299" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture ; Animals ; Atmosphere ; Carbon Dioxide ; Climate ; *Ecosystem ; Fresh Water ; Models, Biological ; Nitrogen
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
    Publication Date: 2000-11-18
    Description: PSD-95 is a neuronal PDZ protein that associates with receptors and cytoskeletal elements at synapses, but whose function is uncertain. We found that overexpression of PSD-95 in hippocampal neurons can drive maturation of glutamatergic synapses. PSD-95 expression enhanced postsynaptic clustering and activity of glutamate receptors. Postsynaptic expression of PSD-95 also enhanced maturation of the presynaptic terminal. These effects required synaptic clustering of PSD-95 but did not rely on its guanylate kinase domain. PSD-95 expression also increased the number and size of dendritic spines. These results demonstrate that PSD-95 can orchestrate synaptic development and are suggestive of roles for PSD-95 in synapse stabilization and plasticity.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉El-Husseini, A E -- Schnell, E -- Chetkovich, D M -- Nicoll, R A -- Bredt, D S -- New York, N.Y. -- Science. 2000 Nov 17;290(5495):1364-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Physiology, University of California, San Francisco 94143, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11082065" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cells, Cultured ; Dendrites/ultrastructure ; Excitatory Postsynaptic Potentials ; Hippocampus/cytology ; Interneurons/cytology/metabolism/*physiology ; Intracellular Signaling Peptides and Proteins ; Membrane Proteins ; Nerve Tissue Proteins/chemistry/genetics/metabolism/*physiology ; Patch-Clamp Techniques ; Presynaptic Terminals/physiology ; Protein Structure, Tertiary ; Pyramidal Cells/cytology/metabolism/*physiology ; Rats ; Receptor Aggregation ; Receptors, AMPA/metabolism ; Receptors, Glutamate/*metabolism ; Receptors, N-Methyl-D-Aspartate/metabolism ; Synapses/metabolism/*physiology ; Synaptic Transmission ; Synaptic Vesicles/physiology ; Transfection
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2000-09-30
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Sinclair, A R -- Ludwig, D -- Clark, C W -- New York, N.Y. -- Science. 2000 Sep 15;289(5486):1875.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11012354" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Conservation of Natural Resources/methods ; *Ecosystem ; Humans ; Residence Characteristics
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    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
    Publication Date: 2000-06-10
    Description: Globally, tropical deforestation releases 20 to 30% of anthropogenic greenhouse gases. Conserving forests could reduce emissions, but the cost-effectiveness of this mechanism for mitigation depends on the associated opportunity costs. We estimated these costs from local, national, and global perspectives using a case study from Madagascar. Conservation generated significant benefits over logging and agriculture locally and globally. Nationally, however, financial benefits from industrial logging were larger than conservation benefits. Such differing economic signals across scales may exacerbate tropical deforestation. The Kyoto Protocol could potentially overcome this obstacle to conservation by creating markets for protection of tropical forests to mitigate climate change.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kremen, C -- Niles, J O -- Dalton, M G -- Daily, G C -- Ehrlich, P R -- Fay, J P -- Grewal, D -- Guillery, R P -- New York, N.Y. -- Science. 2000 Jun 9;288(5472):1828-32.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Conservation Biology, Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA. ckremen@stanford.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10846165" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture ; Carbon ; Conservation of Natural Resources/*economics ; Cost-Benefit Analysis ; Developed Countries ; Developing Countries ; *Ecosystem ; Greenhouse Effect ; Industry ; Madagascar ; *Trees
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
    Publication Date: 2000-07-15
    Description: A half-century policy of forest exploitation and monoculture in China has led to disastrous consequences, including degradation of forests and landscapes, loss of biodiversity, unacceptable levels of soil erosion, and catastrophic flooding. A new forest policy had been adopted in China called the Natural Forest conservation Program (NFCP), which emphasizes expansion of natural forests and increasing the productivity of forest plantations. Through locally focused management strategies, biodiversity and forest resources will be sustained, and downstream regions will be better protected from flooding. This new policy is being implemented with a new combination of policy tools, including technical training and education, land management planning, mandatory conversion of marginal farmlands to forest, resettlement and retaining of forest dwellers, share in private ownership, and expanded research. These policy tools may have wider relevance for other countries, particularly developing countries.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zhang, P -- Shao, G -- Zhao, G -- Le Master, D C -- Parker, G R -- Dunning, J B Jr -- Li, Q -- New York, N.Y. -- Science. 2000 Jun 23;288(5474):2135-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Natural Forest Conservation and Management, State Forestry Administration (SFA), Beijing 100714, P. R. China.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10896587" target="_blank"〉PubMed〈/a〉
    Keywords: Agriculture ; China ; *Conservation of Natural Resources ; *Ecosystem ; *Forestry/education ; *Public Policy ; Research ; *Trees
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    American Association for the Advancement of Science (AAAS)
    Publication Date: 2000-10-14
    Description: The Kyoto protocol aims to reduce carbon emissions into the atmosphere. Part of the strategy is the active management of terrestrial carbon sinks, principally through afforestation and reforestation. In their Perspective, Schulze et al. argue that the preservation of old-growth forests may have a larger positive effect on the carbon cycle than promotion of regrowth.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schulze, D E -- Wirth, C -- Heimann, M -- New York, N.Y. -- Science. 2000 Sep 22;289(5487):2058-9.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Max Planck Institute for Biogeochemistry, Post Office Box 100164, 07701 Jena, Germany. Detlef.Schulze@bgc-jena.mpg.de〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11032555" target="_blank"〉PubMed〈/a〉
    Keywords: *Carbon ; *Carbon Dioxide ; *Conservation of Natural Resources ; *Ecosystem ; *Trees
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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