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Control of lysosomal acid phosphatase expression in man-mouse cell hybrids (1974)

Shows, Thomas B. ; Lalley, Peter A.

Springer

Biochemical genetics 11 (1974), S. 121-139

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ISSN: 1573-4927

Keywords: gene expression ; gene mapping ; lysosomal enzymes ; cell fusion ; gel electrophoresis

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Abstract Lysosomal acid phosphatase activity in human and mouse cells was separated into multiple zones by starch gel electrophoresis. One of the two major zones in the mouse was apparently extinguished when genetic information from man and the mouse was combined in proliferating man-mouse somatic cell hybrids. The evidence suggested that the absence of the mouse lysosomal acid phosphatase (mAP-1) was influenced by the human genome. The gene coding for human acid phosphatase (hAP-1) was shown to be unlinked to the presumed human component which extinguished the mouse acid phosphatase (mAP-1). The mechanism of “extinction” is postulated to be a modification in the processing of the mouse lysosomal enzyme. A dimeric structure was suggested for acid phosphatase-1 of man, mouse, and rat since a single hybrid enzyme was expressed in man-mouse and mouse-rat somatic cell hybrids.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00485769

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Genetics of human-mouse somatic cell hybrids: Linkage of human genes for isocitrate dehydrogenase and malate dehydrogenase (1972)

Shows, Thomas B.

Springer

Biochemical genetics 7 (1972), S. 193-204

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ISSN: 1573-4927

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Chemistry and Pharmacology

Notes: Abstract Based on somatic cell genetic analysis, autosomal gene linkage is reported for the supernatant enzymes of human isocitrate dehydrogenase (IDH) and malate dehydrogenase (MDH) in human-mouse cell hybrids. The IDH, MDH linkage was not linked to the X and E 17 chromosomes or to 12 additional human enzyme markers.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00484817

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Spectrophotometry (0.3 to 1.1µ) of visited and proposed apollo lunar landing sites (1972)

McCord, Thomas B. ; Charette, Michael P. ; Johnson, Torrence V. ; [et al.]

Springer

Earth, moon and planets 5 (1972), S. 52-89

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ISSN: 1573-0794

Source: Springer Online Journal Archives 1860-2000

Topics: Geosciences , Physics

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00562105

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Theoretical studies of diamagnetic properties of the hydrogen molecule ion II. Effect of varying internuclear separation (1972)

Garrett, Thomas B. ; Zeroka, Daniel

New York, NY : Wiley-Blackwell

International Journal of Quantum Chemistry 6 (1972), S. 663-668

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ISSN: 0020-7608

Keywords: Computational Chemistry and Molecular Modeling ; Atomic, Molecular and Optical Physics

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: The diamagnetic susceptibility χ and magnetic shielding σ for H2+ are investigated in the range of internuclear separations R = 1.6 a.u. to R = 2.4 a.u. according to a previously reported technique. From this data values of 〈χ〉 and 〈σ〉, for which nuclear motion due to zero-point vibration and centrifugal stretching is taken into account, are calculated at 300°K. These averages are 〈χ〉 = -0.3902 α2ao3 and 〈σ〉 = 1.096 × 10-5 c.g.s. units which are approximately 3.1% and 1.4% respectively, smaller than the equilibrium values.

Additional Material: 3 Tab.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/qua.560060410

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Theoretical studies of diamagnetic properties of the hydrogen molecule ion. I. Approximate variation-perturbation calculation (1972)

Garrett, Thomas B. ; Zeroka, Daniel

New York, NY : Wiley-Blackwell

International Journal of Quantum Chemistry 6 (1972), S. 651-661

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ISSN: 0020-7608

Keywords: Computational Chemistry and Molecular Modeling ; Atomic, Molecular and Optical Physics

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: A variation-perturbation method, analogous to a technique devised by Das and Bersohn for the study of the hydrogen molecule, is developed for calculation of the diamagnetic susceptibility χ and magnetic shielding σ and is applied to a study of the hydrogen molecule ion. Two approximations are investigated-in a first approximation, χ = -0.37814α2ao3 and σ = 1.112 × 10-5 c.g.s. units and in a second approximation, χ = -0.37569α2ao3 and σ = 1.128 × 10-5 c.g.s. units.

Additional Material: 1 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/qua.560060409

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Heterogeneous nucleation and growth of spherulites from a polycaprolactone (poly(1-oxy-6-oxohexamethylene)) melt (1974)

Goldfarb, Louis ; Garrett, Thomas B. ; Rittenhouse, James R. ; [et al.]

New York : Wiley-Blackwell

Die Makromolekulare Chemie 175 (1974), S. 2483-2488

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ISSN: 0025-116X

Keywords: Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology , Physics

Description / Table of Contents: Es wird über den Beginn einer Untersuchung zur Kristallisationskinetik von Polycaprolacton (Poly(1-oxy-6-oxohexamethylene) (1)) berichtet. Die primäre Keimbildung und das primäre Sphärolith-Wachstum aus der Polymerschmelze werden bei hinreichend hohen Temperaturen verfolgt, wodurch sichergestellt ist, daß das Wachstum der Kristallite durch Keimbildung bestimmt ist. Die kinetischen Daten werden weitgehend mit Hilfe des Avrami-Modells interpretiert, welches sich gut auf die Kristallisation von 1 anwenden ließ.

Notes: A kinetic crystallization study of polycaprolactone (poly(1-oxy-6-oxohexamethylene) (1)) has been initiated to investigate the primary nucleation and primary spherulitic growth from a polymer melt at temperatures that are high enough to insure nucleation-limited crystallite growth. The analysis of the kinetic data is largely made on the basis of an Avrami model which proved to be well suited for the interpretation of the crystallization of 1.

Additional Material: 1 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/macp.1974.021750821

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